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琥珀酰亚胺

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The determination of amino acids in blood clam antianaemia oral liquid using HPLC-AccQ-Tag method is reported. The oral liquid reacted with 6-aminoquinolyl-N-hydroxysuccini-mdyl carbamate. Then, the corresponding derivatives were analyzed with an HPLC. The chromatographic conditions were AccQ-TagTM C18 column for amino acids analysis (3.9mm×15cm); mobile phase of program elution sodium acetate solution(pH5.02), acetonitrile, Milli-Q water. The amino acids'AQC deriatives were detected at 248nm with a UV-detector. Eighteen kinds of amino acids were completely determined in 35 minutes.

以6-氨基喹啉-N-羟基琥珀酰亚胺基氨基甲酸酯为衍生剂,与毛蚶抗贫血口服液中的氨基酸柱前定量衍生,用WatersHPLC仪,AccQ-TagTM专用C18柱(3.9mm×15cm),以140mmol·L-1的醋酸钠溶液(pH5.02)为溶剂A,乙腈为溶剂B,超纯水为溶剂C,进行梯度洗脱,检测波长为248nm,35min测试完毕。

Methods The amino acids in the injections were pretreated with 6-aminoquinolyl-N-hydroxysuccinimdyl separately and their derivatives were analyzed on Waters 2695 HPLC using AccQ-Tag column. Gradient eluents consisted of sodium acetate solution (pH 4.95), acetonitrile and water. The Detection wavelength was 248 nm and column temperature 37℃.

采用AccQ-Tag法,以6-氨基喹啉-N-羟基琥珀酰亚胺基甲酸酯为衍生试剂,与复方氨基酸注射液(18AA-V)中17种氨基酸柱前衍生,用Waters 2695 HPLC仪器,AccQ-Tag柱,以醋酸钠(pH 4.95)缓冲液为流动相A,乙腈为流动相B,水为流动相C进行梯度洗脱,检测波长为248 nm,柱温为37℃,进样量为5μL。

The derivative is prepared by glycin reacts with the mid-product, which is produced in the combination of PASP synthesis, and the corrosion and scale inhibition efficiency are preliminary investigated.

将合成聚天冬氨酸时产生的中间产物聚琥珀酰亚胺和甘氨酸反应,合成聚天冬氨酸的衍生物,并初步探讨了它的缓蚀阻垢性能。

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