琥珀酰亚胺

The resting cell of Alcaligenes eutrophus 112R 4 can catalyze the hydrolysis of hydantoin, dihydropyrimidine and succinimide effectively, but not function to 5-monosubstituted hydantoins or 5,5'-disubstituted hydantoins.

该菌能水解海因、二氢尿嘧啶和琥珀酰亚胺，且对琥珀酰亚胺活力最高，但不水解 5 单取代海因和5 ，5' 双取代海因，因而被确定为含有酰亚胺酶。

The synthetic progress of polysuccinimide using maleic acid as original material was studied by two steps of aminization and polymerization. Changes of reactant and product composition in aminization reaction step was studied by using bromine value analysis method. It was found that amine salt and amide were main products in this step.

对以马来酐为原料合成聚琥珀酰亚胺的两个反应过程进行了研究，通过溴价测定法研究了胺化反应阶段反应物及产物各组分的变化情况，确定胺化反应阶段的产物组分主要是胺盐和酰胺。

Two kinds of polyaspartic acid derivates, i.e. PEG-g-PAsp and PEG-g-PDEA, were prepared through the ring-opening reaction of polysuccinimide by CH3O-PEG-NH2, followed by alkaline hydrolysis and aminolysis, respectively.

通过胺端基聚乙二醇(CH3O-PEG-NH2)开环聚琥珀酰亚胺，进一步碱解和胺解制备了聚乙二醇接枝聚天冬氨酸和聚乙二醇接枝聚乙二胺基天冬酰胺两种聚天冬氨酸衍生物。

Was synthesized from succimide by bromination with bromine,methylation with dimethyl sulfate and the reaction of indolyl magnesium bromide with 2,3-dibromoN-methylmaleimide.

以琥珀酰亚胺为起始原料，经过溴化、甲基化后再与吲哚溴化镁加成反应合成了2-溴-3-(1H-吲哚-3)-N-甲基马来酰亚胺，总收率44.8%，其结构经1H NMR和IR确证。

Seven of them have not been reported.Their structures were confirmed by IR,~1HNMR,MS,and element analysis. 4.Meanwhile,the green methylation procedure of imides was developed by using dimethyl carbonate as methylation reagent.A series of imides,for example,phthalimide,3,4-dibromo-maleimide and succincide were used for substrates.The effects of DABCO(1,4-diazabicyclo [2.2.2]octane)and DBU(1,8-diazabicyclo[5.4.0]undec-7-ene)as a catalyst in this kind of reactions were investigated.2-Bromo-3-(1-methylindolyl-3-yl)-1-methyl-1H-pyrrole-2,5-dione was prepared by using dimethyl carbonate,which further expanded the use of dimethyl carbonate,as a green agent in organic synthesis.

在以硫酸二甲酯为甲基化试剂对3，4-二溴马来酰亚胺进行N-甲基化反应合成3，4-二溴-N-甲基马来酰亚胺的同时，以碳酸二甲酯为甲基化试剂，对3，4-二溴马来酰亚胺、邻苯二甲酰亚胺、琥珀酰亚胺等酰亚胺类化合物的N-甲基化反应进行了研究；考察了1，4-二氮杂双环[2.2.2]辛烷，1，8-二氮杂双环[5.4.0]十一碳-7-烯、碳酸钾和四丁基溴化铵等作为催化剂对碳酸二甲酯N-甲基化反应的反应时间和收率等的影响，并应用碳酸二甲酯为甲基化试剂，合成了N-甲基-3-溴-4-(1-甲基-吲哚-3)-马来酰亚胺。

The microorganism can utilize succinimide as a sole carbon source and nitrogen source, which indicates the presence of a complete transformation pathway of succinimide, and a hydantoin-cleavi...

真养产碱杆菌 1 1 2R4 能在以琥珀酰亚胺为唯一碳、氮源的培养基上生长，表明该菌中存在琥珀酰亚胺完整的转化途径。

In order to improve the stability and mechanical properties in moist state,the gelatin nanofibrous membranes were chemically crosslinked by 1-ethyl-3-dimethyl-aminopropyl carbo-diimide hydrochloride and N-hydroxyl succinimide.

采用1-乙基-(3-二甲基氨基丙基)碳二亚胺和N-羟基琥珀酰亚胺对明胶纳米纤维膜材料进行化学交联处理，改善了材料的耐水性、热稳定性和力学抗拉性能。

The hydrophobic core serves as a reservoir for water-insoluble drugs.Hence,these nanoparticles can be used as carriers for hydrophobic drugs.For the synthesis of cholesterol-modified glycol chitosan conjugates,a carboxyl group was initially introduced to cholesterol molecule using succinic anhydride,and then covalently coupled with the primary amino group of glycol chitosan in the presence of 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide hydrochloride and N-hydroxyl succinimide.

本文采用二步反应将胆固醇接枝到乙二醇壳聚糖，首先将胆固醇进行羧基化，将胆固醇与琥珀酸酐反应生成胆固醇半琥珀酸酯，然后用1-乙基-3-(3-二甲基氨丙基)碳二亚胺盐酸盐与N-羟基琥珀酰亚胺作为偶联剂，将胆固醇半琥珀酸酯的羧基与乙二醇壳聚糖主链的氨基进行反应，得到胆固醇疏水改性乙二醇壳聚糖共聚物。

With land area of 2,800M2 and completed quality supervision test instrument, its annual sales amount reaches 30,000,000 RMB. Its main products, Succinimide,butanimide,2.5-diketopyrrolidine;N-bromobutanimide or N-bromosuccinimide;N- chlorosuccinimide (N-chlorobutanimide);Bromoacetonitrile,Bromomethyl cyanide; Quinoline;P-Bromophenol;4-Bromophenol;N.N'- dicyclohexylcarbodiimide;S-3-Hydroxy-γ-Butyrolactone;2.3-Dihydrofuran;Ammonia water, Ammonium hydroxide; sell well in the US, South Korea, Europe and other countries and are praised highly by all clients.

占地面积2800M2，年销售额3000万元，公司拥有完备的质量监测检验仪器和手段，主要产品有：琥珀酰亚胺、N-溴代琥珀酰亚胺、N-氯代琥珀酰亚胺、溴乙晴、喹啉（95%）、喹啉（ 98%）、对溴苯酚、N.N'-二环已基碳化二亚胺、s-3-羟基-γ-丁内酯、2.3-二氢呋喃、氨水、氢氧化胺，产品远销美国、韩国、欧洲等国家和地区，深受用户青睐。

The glycyrrhizic acid antigen is prepared through the process including following steps: dissolving glycyrrhizic acid in N, N-dimethyl formamide, dioxane or dimethyl sulfoxide, heliophobically adding N-hydroxy succinimide, reacting with dicyclohexylcarbodiimide at 0-10 deg.c for 2-5 hr; and reacting with carrier protein at normal temperature for 4-6 hr to obtain glycyrrhizic acid antigen.

本发明所提供的甘草酸抗体，是用甘草酸抗原免疫动物，然后从被免疫动物的血清中分离得到的；所述甘草酸抗原按如下过程制备：先将甘草酸溶解在N，N-二甲基甲酰胺、二氧六环或二甲基亚砜中，避光加入N-羟基琥珀酰亚胺，然后在0-10℃条件下与二环己基碳二亚胺反应2-5小时；接着与载体蛋白常温反应4-6小时，得到甘草酸抗原。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。