琥珀酰

The resting cell of Alcaligenes eutrophus 112R 4 can catalyze the hydrolysis of hydantoin, dihydropyrimidine and succinimide effectively, but not function to 5-monosubstituted hydantoins or 5,5'-disubstituted hydantoins.

该菌能水解海因、二氢尿嘧啶和琥珀酰亚胺，且对琥珀酰亚胺活力最高，但不水解 5 单取代海因和5 ，5' 双取代海因，因而被确定为含有酰亚胺酶。

The analysis of 1H NMR showed that the succinyl group was successfully conjugated to the amino group of chitosan molecule, and the degree of substitution of Suc-Chi values increased with increasing succinic anhydride/amino mole ratio or reducing the molecular weight of chitosan.

利用壳聚糖和琥珀酰酐反应合成了N-琥珀酰壳聚糖，1H NMR分析表明通过反应可在壳聚糖的侧氨基引入亲水性的羧基，增加琥珀酰酐／氨基的摩尔投料比或者选择分子质量较小的壳聚糖，有利于提高N-琥珀酰壳聚糖的琥珀酰化度。

METHODS: A series of N-octyl-N'-succinyl chitosan labeled with fluorescein, were incubated with HepG2 liver cancer cells, K562 leukemia cells, A549 human lung cancer cells, and BGC cancer cells respectively and followed by using flow cytometry and enzyme-linked immunosorbent assay to assess the affinity and inhibition of N-octyl-N'-succinyl chitosan for the four kinds of tumor cells already mentioned.

用异硫氰酸荧光素对N-正辛基－N'-琥珀酰基壳聚糖进行标记，再分别与人肝癌细胞(HepG2)、人白血病细胞(K562)、人非小细胞肺癌细胞(A549)及人胃癌细胞共培养，通过流式细胞仪及酶联免疫检测仪测定N-正辛基－N'-琥珀酰基壳聚糖对肿瘤细胞的亲和性及抑制力。

Therefore, the metabolic pathway from soybean oil to erythromycin was presumed as follows: soybean oil is metabolized into TCA pathway to generate much α ketoglutaric acid and then generate succinyl CoA by strengthening TCA pathway, and the methylmalonyl CoA is formed from succinyl CoA by isomerization. Finally, methylmalonyl CoA can be used as the precursor for the biosynthesis of erythromycin.

推测豆油经过红色糖多孢菌代谢后进入红霉素合成的一条可能途径：豆油经过代谢后进入TCA循环，并强化了TCA循环的通量，产生了大量α酮戊二酸，再生成琥珀酰CoA，琥珀酰CoA在甲基丙二酰CoA异构酶的作用下生成甲基丙二酰CoA作为红霉素合成的前体。

CoA by strengthening TCA pathway, and the methylmalonyl??CoA is formed from succinyl??CoA by isomerization. Finally, methylmalonyl??CoA can be used as the precursor for the biosynthesis of erythromycin.

餐？戊二酸，再生成琥珀酰CoA，琥珀酰CoA在甲基丙二酰CoA异构酶的作用下生成甲基丙二酰CoA作为红霉素合成的前体。

They are, 4 21-amidohydrocortisone Ba1～Ba4, 10 21-amidoprednisolone Bb1～Bb10, 4 21-amidomethylprednisolone Bc1～Bc4, 4 21-amidodexamethasone Bd1～Bd4, 1 21-amidobetamethasone Be1, 1 21-amidoRS Bf1, 1 21-amidocortisone Bg1, 1 21-amidoprednisone Bh1. The amido groups were acetamido, nicotinamido, hemesuccinamido, benzoylamido, methanesufonamido, or arylsufonylamido.

包括：4个21-酰胺基氢化可的松（Ba1～Ba4），10个21-酰胺基氢化泼尼松（Bb1～Bb10），4个21-酰胺基甲泼尼龙（Bc1～Bc4），4个21-酰胺基地塞米松（Bd1～Bd4），1个21-酰胺基倍它美松（Be1），1个21-酰胺基RS（Bf1），1个21-酰胺基可的松（Bg1），1个21-酰胺基强的松（Bh1）。21-酰胺基分别为乙酰胺基、烟酰胺基、单琥珀酰胺基、苯甲酰胺基、甲烷磺酰胺基或取代苯磺酰胺基等。

This study was based on the soy protein isolates as raw materials. Chemical modification( acetylation,succinylation ,phosphorylation and urea modification) of SPI were used to improve adhesive strength and water resistance of SPI-based plywood adhesives. Then two modified ways combined were applied to SPI and their adhesive properties were studied. This research also characterized the thermal and adhesive properties of two major soy protein components 7S conglycinin and 11S glycinin after urea modification. Finally, the mechanism of improving SPI's adhesive properties was preliminarily discussed.

本文是以大豆分离蛋白为原料，进行SPI的化学修饰以提高其胶粘特性；采用了磷酸化试剂三聚磷酸钠、乙酰化试剂乙酸酐、琥珀酰化试剂琥珀酸酐和有机溶剂尿素修饰和变性SPI，研究修饰和变性后的SPI作为木材胶粘剂的胶粘性与耐水性，同时研究了两种方法复合修饰SPI对其粘度、胶粘强度和耐水性的影响；然后以SPI为原料，进行7S和11S球蛋白的提取以及胶粘特性的研究，对SPI起胶粘特性的机理进行了初步探讨。

Seven of them have not been reported.Their structures were confirmed by IR,~1HNMR,MS,and element analysis. 4.Meanwhile,the green methylation procedure of imides was developed by using dimethyl carbonate as methylation reagent.A series of imides,for example,phthalimide,3,4-dibromo-maleimide and succincide were used for substrates.The effects of DABCO(1,4-diazabicyclo [2.2.2]octane)and DBU(1,8-diazabicyclo[5.4.0]undec-7-ene)as a catalyst in this kind of reactions were investigated.2-Bromo-3-(1-methylindolyl-3-yl)-1-methyl-1H-pyrrole-2,5-dione was prepared by using dimethyl carbonate,which further expanded the use of dimethyl carbonate,as a green agent in organic synthesis.

在以硫酸二甲酯为甲基化试剂对3，4-二溴马来酰亚胺进行N-甲基化反应合成3，4-二溴-N-甲基马来酰亚胺的同时，以碳酸二甲酯为甲基化试剂，对3，4-二溴马来酰亚胺、邻苯二甲酰亚胺、琥珀酰亚胺等酰亚胺类化合物的N-甲基化反应进行了研究；考察了1，4-二氮杂双环[2.2.2]辛烷，1，8-二氮杂双环[5.4.0]十一碳-7-烯、碳酸钾和四丁基溴化铵等作为催化剂对碳酸二甲酯N-甲基化反应的反应时间和收率等的影响，并应用碳酸二甲酯为甲基化试剂，合成了N-甲基-3-溴-4-(1-甲基-吲哚-3)-马来酰亚胺。

The microorganism can utilize succinimide as a sole carbon source and nitrogen source, which indicates the presence of a complete transformation pathway of succinimide, and a hydantoin-cleavi...

真养产碱杆菌 1 1 2R4 能在以琥珀酰亚胺为唯一碳、氮源的培养基上生长，表明该菌中存在琥珀酰亚胺完整的转化途径。

With land area of 2,800M2 and completed quality supervision test instrument, its annual sales amount reaches 30,000,000 RMB. Its main products, Succinimide,butanimide,2.5-diketopyrrolidine;N-bromobutanimide or N-bromosuccinimide;N- chlorosuccinimide (N-chlorobutanimide);Bromoacetonitrile,Bromomethyl cyanide; Quinoline;P-Bromophenol;4-Bromophenol;N.N'- dicyclohexylcarbodiimide;S-3-Hydroxy-γ-Butyrolactone;2.3-Dihydrofuran;Ammonia water, Ammonium hydroxide; sell well in the US, South Korea, Europe and other countries and are praised highly by all clients.

占地面积2800M2，年销售额3000万元，公司拥有完备的质量监测检验仪器和手段，主要产品有：琥珀酰亚胺、N-溴代琥珀酰亚胺、N-氯代琥珀酰亚胺、溴乙晴、喹啉（95%）、喹啉（ 98%）、对溴苯酚、N.N'-二环已基碳化二亚胺、s-3-羟基-γ-丁内酯、2.3-二氢呋喃、氨水、氢氧化胺，产品远销美国、韩国、欧洲等国家和地区，深受用户青睐。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。