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Objective To study coccoid forms of Helicobacter pylori possible recovery in vitro and in vivo, reveal its potential route of transmission.

目的 对幽门螺杆菌(Helicobacter pylori, Hp)球形体进行体内、外回复原形的比较研究,揭示其潜在的传播途径。

Coccoid forms of Hp were inoculated in four culture mediums as well as animals and the possible recovery was observed in vitro and vivo.

结果 Hp球形体在4种再生培养基中均未能回复生长;而在感染小鼠的体内却观察到了Hp球形体的回复定植。

But the level of colonization and pathological change of the group of coccoid forms were significantly lower compared with the group of spiral forms.

Hp球形体作为一种低水平代谢休眠体,代谢活性及毒力均有所减弱,但仍具有潜在的致病性。

RESULTS Hp can grow in liquid media in room temperature, and 3 out of 18 strains of coccoid Hp reverted to bacterial.

结果 Hp可在室温液体中繁殖,18株中观察到3株球形体Hp在室温下的返祖,除常见球形变外的Hp杆状弯曲、长杆状、短杆状、长丝体、巨球体、丝球体、原生质体及细小"S"和弧形变异。

Results The recovery and regrowth in vitro of coccoid forms of Hp did not he observed in our applied four kinds of culture medium. Parts of coccoid forms of Hp occured reversion and colonization in mice stomach.

Hp螺旋体感染组在小鼠胃内的定植密度较高,且胃粘膜下可见大量炎症细胞浸润;而球形体感染组并未见到小鼠胃粘膜组织的明显炎症损伤,且仅有少量回复的螺旋体定植。

This experiment results suggested coccoid forms of Hp still possess potential pathogenicity, and provides an impetus for this hypothesis that coccoid forms of Hp be viable but nonculturable.

本研究支持部分Hp球形体具有活力但体外不能培养成活这一假说,提示"粪-口"传播应引起更多的关注。

The results show that the shape of fly ash particles is various. Most particles are irregular, some are baculiform and very few particles are spherical and flocculent.

实验结果表明,飞灰颗粒形态多样化,其中以不规则形状聚合体居多,球形体、絮状集合体相对较少,少数颗粒为棒状集合体。

The C3A spheroids displayed multilayer cell morphology, characterized by a large number of tight junctions, polar cells, and bile canaliculi, similar to spheroids of primary hepatocytes.

这个C3A球形体显示出多层细胞的形态学特征,包括有大量的紧密连接、极性细胞及胆小管,这与原代肝细胞球形体相似。

Results We discovered that under starvation conditions, the long, flexible rod cell of Cytophaga hutchinsonii would bend and turn into circular cell. The circular cell failed to produce carboxymethyl cellulase. Some of the circular cells might further wind around and turn into tiny spherical cells.

发现在饥饿状态下,长杆状菌体开始逐渐弯曲,菌体两端靠近成环形,环形菌体又进一步盘绕收缩成微小球形体,微小球形体在一定条件下能像生孢噬纤维菌的小孢囊一样萌发形成长杆状菌。

This paper discusses the significance of a new tool, the Inertia Moment Projection ellipsoid, for the deformation description and strain analysis of structural objects with arbitrary shape.

本文讨论了一种新的数学工具,即惯量投影椭球,在具有任意形状构造变形体的变形描述与应变分析中的意义。

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In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国,慢性酒精中毒,肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题,你可以随时联系我。

Very pretty, but the airport looks more fascinating The other party wisecracked.

很漂亮,不过停机坪更迷人。那人俏皮地答道。