环胺

The catalytic system composed of NHPI and transition metal ion can catalyze effectively ethane into acetic acid,cyclane into dicarboxylic acid,toluene into benzoic acid,alkene into epoxide,alkyne into acetylenic ketone,and amide into imide;NHPI used alone can catalyze adamantane to be carbonylated,hydrogen peroxide prepared by oxidization alcohol;NHPI combined with as...

NHPI与过渡金属离子组成的催化体系能高效地催化乙烷氧化为乙酸、环烷烃氧化为二元羧酸、甲苯氧化为苯甲酸、烯烃氧化为环氧化物、炔烃氧化为炔酮、酰胺氧化为酰亚胺；NHPI单独使用能催化金刚烷发生氧化羰基化反应、催化氧化醇制取过氧化氢；NHPI与有机助催化剂如偶氮二异丁腈、溴化季铵盐、蒽醌和醇等也能催化分子氧氧化反应。

The selectivity of cyclization of carbodiimide 2 with primary amine was studied and the result showed that the anomalous product being cyclized from arylamino group was formed preferencially.

研究了碳二亚胺2与伯胺成环反应的选择性，结果表明优先生成反常的芳氨基成环产物，利用中间体可能的构型解释了实验结果。

Firstly, 3-ethylthiobutanal was prepared from crotonaldehyde reacting with ethanehiol in triethylamine with high yield. Secondly, methyl acetoacetate was converted to 6-ethylthiohept-3-en-2-one by three steps via hydrolysis, condensation with 3-ethyltio-butanal and dehydration, then 6-ethylthiohept-3-en-2-one was cycloco ndensed with dimethyl malonate by Michael addition and Claisen condensation, followed by saponification and decarboxylation to give the intermediate of 5-(2-ethylthiopropyl)-cyclohexane-1,3-dione.

首先，以巴豆醛与乙硫醇为原料，在三乙胺的催化作用下高收率制得3-乙硫基丁醛；然后从乙酰乙酸甲酯出发，通过碱水解、与3-乙硫基丁醛缩合、脱水三步反应合成6-乙硫基-3-烯-2-庚酮，接着6-乙硫基-3-烯-2-庚酮与丙二酸二甲酯通过Michael加成和Claisen缩合成环，再通过皂化和脱羧反应生成中间体5-[2-丙基]-1，3-环己二酮；再与丙酸酐反应丙酰化，最后与0-3-氯-2-丙烯基羟胺肟化，得到目标化合物烯草酮。

Finally, in multinuclear macrocyclic polyamine derivatives, we found that cyclen-based oligomers form polymer complex with DNA, thus protect DNA from enzymatic degradation efficiently.

在多核大环多胺方面，我们合成了基于大环多胺的寡聚物，研究发现该类物质可与DNA形成复合物，从而有效地保护DNA免于酶解。

The macrocyclic polyamines are a kind of excellent ligands and have a substantially high binding affinity with transition metal ions. Macrocyclic polyamine metal complexes as enzyme models are widely used in chemical biology, medicine and gene therapy. 1, 4, 7, 10-tetrazacyclododecane is a representative macrocyclic polyamines compound and shows high binding affinity with transition metal ions, such as Zn, Cu and Co. Their metal complexes especially multinuclear complexes were widely used in DNA, RNA recognition.

大环多胺化合物是一类性质独特的优秀配体，具有良好的金属配位能力，其金属配合物作为人工酶模型广泛应用于核酸结构及功能研究、基因表达与调控、抗癌药物的研制等生物、化学和医学领域。1，4，7，10-四氮杂十二烷是典型的大环多胺化合物，对过渡金属离子Zn， Cu and Co有良好的配位能力，这些金属配合物特别是多核金属配合物被广泛应用于DNA识别中。

Methods In the treatment group which received tetragenous treatment,the 31 cases were administered additional doses of doxycycline and chinese herbs in addition to routine administration of cyclophosphamide and prednisone while in the control group the 18 cases were only given prednisone and cyclophosphamide.

治疗组 31例采用四联疗法，即除常规应用环磷酰胺、强的松外，另加大剂量的强力宁及中药治疗；对照组 1 8例给予强的松和环磷酰胺治疗。

A new macrocyclic ligand was synthesized by the condensation of 1,3-propylenediamine and triamine.

用丙二胺和三-胺，在无水甲醇中进行环缩合反应，生成了一个杂原子大环配体。

Phenolic agent in alkaline lignin separated fromthe the black liquid can result in a chain etherized reaction on cycloalkanes by alkaline distilling so as to make lignin change its property.

从蒸煮黑液中分离的碱木素苯环上的酚羟基可与环氧烷基胺发生醚化接枝反应，从而使木素胺化改性。

Glass-epoxy system used for steel parts, casting a variety of mechanical parts or electronic components as a sealing material, the preparation of polyamide anti-corrosion paintings, as well as a zinc-rich epoxy primer, epoxy primer Iron Cloud, epoxy stone painting, epoxy paint, bituminous coal, chemical corrosion, paint, etc. have also been used widely

用于制环氧玻璃钢制件，浇铸各种机械零件或作为电子元件的密封材料，配制聚酰胺防腐涂料，以及用作环氧富锌底漆、环氧云铁底漆、环氧石漆、环氧煤沥青漆等，在化工防腐，涂料等方面也有广泛用途。

Secondly, the syntheses of functionalized macrocyclic polyamine complexes containing nucleobases, PNA monomer, imidazolium side, crown ether, ferrocenyl side and their interaction with DNA were studies, respectively.

在功能化大环多胺方面，我们合成了含有碱基、PNA单体、咪唑鎓盐、冠醚、二茂铁等功能化基团的大环多胺衍生物及金属配合物，并研究了其与DNA的相互作用。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。