环胺

They were two new compounds, [cyclo(Pro-Val-Phe-Phe-Pro-Val-Phe-Ser-Leu),7],[2-N-(1-methoxycarbonylethyl)guanosine, 10], and eight known compounds,(p-hydroxybenzoic acid, 1),(methyl succinate, 2),(russulaceramide, 3),(phenylalanine, 4),(guanine, 5),(β-carboline, 6),(uridine, 8), and (adenosine, 9). All the compounds were isolated from Amanita exitialis for the first time.

分别为：对羟基苯甲酸(p-hydroxybenzoic acid，1)、丁二酸二甲酯(methyl succinate，2)、神经酰胺(russulaceramide，3)、苯丙氨酸（phenylalanine，4）、鸟嘌呤核苷(guanine，5)、β-咔啉(β-carboline，6)、环（脯氨酸-缬氨酸-苯丙氨酸-苯丙氨酸-脯氨酸-缬氨酸-苯丙氨酸-丝氨酸-亮氨酸） [cyclo(Pro-Val-Phe-Phe-Pro-Val-Phe-Ser-Leu)，7]、尿嘧啶核苷(uridine，8)、腺嘌呤核苷(adenosine，9)、2-N-(1-甲氧羰基乙基)鸟苷[2-N-(1-Methoxycarbonylethyl)guanosine， 10]。10个化合物均为首次从致命鹅膏中分离得到，其中化合物7和10为新化合物。

Bezaldehyde was used as protective agent in first method.S-Epichloeohydrin was aminated and acidulated to give(2S)-1-Amino-3-chloro-propanol Salts.The acetylation of (2S)-1-Amino-3-chloro-propanol by acetic anhydride produced the intermediate-N-[2--3-chloropropyl]acetamide.And then at 20℃,in the presence of lithium tert-butoxide,benzyl 3-fluoro-4-morpholinophenyl carbamate react with-N-[2--3-chloropropyl]acetamide to give linezolid in total yield of 43.6%.

路线一采用苯甲醛作保护剂，使S-环氧氯丙烷氨解、酸化生成S-1-氨基-3-氯-2-丙醇盐酸盐，然后经乙酰化反应后，生成中间体-N-[2-乙酰氧基-3-氯丙基]乙酰胺，再用N-(3-氟-4-吗啉苯基)氨基甲酸苄酯和中间体在催化剂叔丁醇锂存在下25℃反应生成利奈唑酮，总产率达到43.6%。

In the process, 2, 4-difluoroaniline is used to carry out ammoniated reaction. Then through a series of similar reactions, the important intermediate of temafloxacin, which is called 7-chloro-6-fluoro-1-(2, 4-difluorophenyl)-1, 4-dihydro-4-oxo-3-quinoline acid, is gained.

与环丙沙星和二氟沙星类似，用2，4-二氟苯胺进行胺化反应，再进行一系列类似的反应，制得合成替马沙星的关键中间体7-氯-6-氟-1-（2，4-二氟苯基）-1，4-二氢-4-氧代喹啉-3-羧酸。

RESULT:Jinkui Shenqi Pill has good antagonizing effect for DNA damage caused by cyclophosphamide.

结果：金匮肾气丸对由环磷酰胺所致DNA损伤具有良好的拮抗作用。

Chlorine atoms were selectively introduced into the chlorin ring based on different reactivity between vinyl group at 3-position and 20-meso position by electrophilic addition and electrophilic substitution using hydrogen peroxide/hydrochloric acid, N-chlorosuccinimide, hydrogen chloride (or concentrated hydrochloric acid) as chlorinating reagent.

以过氧化氢/盐酸、N-氯代丁二酰亚胺、氯化氢为氯化剂，根据3-乙烯基和20-meso-位的不同化学反应活性，通过亲电加成和亲电取代反应，在二氢卟吩环上选择性地引进氯原子，完成8种未见报道的具有叶绿素-a基本碳架的氯代二氢卟吩衍生物的合成。

ABSTRACT:Objective To investigate the influence of Angelica sinenisis injection on bone marrow histology and ultrastructure in mice damnified by cyclophosphamide.

目的 探讨当归注射液对环磷酰胺损伤小鼠骨髓细胞组织形态及超微结构的保护作用。

Synthetic technology of a new epoxy firming agent is briefly introduced. Its principal properties were studied.

简要介绍了缩醛胺环氧固化剂的合成工艺，并对产品主要性能进行了研究。

In 16 month- aged mice, TP (50, 200mg/kg, ig) also showed potentiating effect on PFC response.

TP（200，400mg/kg，ig）可促进正常小鼠的PFC反应，并可对抗环磷酰胺（10mg/kg ip）和冷水（14±1℃）游泳应激所致的PFC反应降低；TP（50.200mg/kg）可使16月龄老年小鼠低下的PFC反应恢复至正常3月龄年轻小鼠水平。

J Am Coll Cardiol,1991;17:509［15］ Shimizu A,Nozaki A,Rudy Y,et al.Onset of induced atrial flutter in the canine pericarditis model ［J］.J Am Coll Cardiol,1991,17:1 223［16］ Stevenson WG,Khan H,Sager P,et al.Identification of reentry circuit sites during catheter mapping and radiofrequency ablation of ventricular tachycardia late after myocardial infarction ［J］.

在冠状窦起搏周长为300 ms和静脉给予1 mg/kg氟卡胺后，在房扑组病例中SD2均由上至下进行性延迟，指示第二个心房波激动主要是由间隔激动沿三尖瓣环逆钟向兴奋右房游离壁所致，显示出跨界嵴传导功能性阻滞。

At this time,priming with 25 IU/ml mouse IFN about 12-24 h and then induced with NDV and superinduced with cycloheximide(20μg/ml) and actinomycin D(2μg/ml),the titer of IFN in the media would be 10~5IU/ml approximately, or 10~5IU...

用25IU/ml鼠IFN起动12—24小时，用NDV作诱生剂，并采用环己亚胺(20μg/ml)和放线菌素D(2μg/ml)进行超诱导，IFN产量可高达1×10~6IU/ml左右，比活接近1.3×10~5IU/ml蛋白。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失