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Results: the results showed that extracts of Artemsia dracunculus L. at the dose of 7.5%,3.75%,1.875% 20 ml/kg.w, can cause a signficant increase of WBC (P.05), thymus index, spleen index,(P.05) phagocytic rate and phagocytic index of phagocyte,(P.05) the transformation rate of the spleen lymphocytes,(P.05) and the serum IL-2(P.05),serum hemolysin concentration 50%( P.05)in immunodepressed mice. Conclusions: extracts oil from Artemsia dracunculus L. can significantly enhance the non-specific, cell-mediated and humoral immunological function in immunodepressed mice.

结果:与模型组比较,椒蒿挥发油各组均能升高小鼠外周血白细胞数(P<0.05);均能升高胸腺指数(P<0.05)、脾指数(P<0.05);均能提高免疫受抑小鼠腹腔巨噬细胞的吞噬率,吞噬指数(P<0.05);均能升高脾淋巴细胞转化率(P<0.05);椒蒿挥发油各组血清IL-2值明显高于环磷酰胺对照组(P<0.05);椒蒿挥发油各组均可升高小鼠的血清半数溶血值(P<0.05)。

We selected mecA gene and femA factor asβ-lactam antibiotic-resistant genes, ermA, ermC, msrAgene as macrolides-lincosamids antibiotic-resistant genes, norA, grlA, gyrA, gene as Quinolonesantibiotic-resistant genes, and tetM gene as Tetracycline antibiotic-resistant genes on the basis of the latestresearch. We designed primers with GenBank enunciable gene sequence, cloned the drug resistantgenes, and sequenced these genes.

根据国内外最新文献报道,筛选出对β-内酰胺类抗生素耐药的mecA基因及辅助因子femA;对大环内酯类及林可霉素类抗生素耐药的ermA、ermC、msrA基因,对喹诺酮类抗菌药物耐药的norA、grlA和gyrA基因及对四环素类抗生素耐药的tetM基因作为拟选的主要耐药基因,分别设计PCR扩增的特异性引物,进行克隆。

Methods Study the effect of G. lucidum spores oil (at the dose of 2.5,1.25,0.725 g/kg) on reducing the toxicity of the Cy chemotherapy and 60Co radiotherapy by detecting the number of the peripheral blood leucocyte, the number of bone marrow karyota;spleen index, thymus index of normal mice and H22-bearing mice by carbon clearance test and serum erythrocytolysin test. Results It showed that G.

方法以正常和 H22荷瘤小鼠为对象,通过检测外周血 WBC数、骨髓有核细胞数、脾脏指数、胸腺指数来观察口服灵芝孢子油(2.5,1.25,0.625 g/kg)对于环磷酰胺化疗及60Co放疗的减毒作用;通过小鼠碳廓清实验、血清溶血素测定实验检测药物对 H22荷瘤小鼠免疫功能的影响。

METHOD: The following tests were made:①test with of hemopoietic inhibition induced by cyclophosphamide on mice,②Carban particles clearance test,③Erythrolysin formetien test,④Swimming test,⑤Hypoxia test,⑥Sedation test,⑦Hypnosis test.

①由环磷酸胺引起的小鼠造血系统抑制模型;②小鼠碳粒廓清试验;③小鼠溶血素形成试验;④小鼠游泳试验;⑤小鼠耐缺氧试验;⑥小鼠旷野活动试验;⑦由戊巴比妥钠引起的小鼠催眠模型。

Objective: To study the Eucommia total polysaccharides on liver injury induced by cyclophosphamide in mice.

目的:研究杜仲总多糖对环磷酰胺所致肝损伤小鼠的影响。

Eucommia total polysaccharides of cyclophosphamide-induced liver injury in mice have better protection.

杜仲总多糖对环磷酰胺致小鼠肝损伤有较好的保护作用。

MethodsThe immunosuppressed mice were induced by cyclophosphamide and Fortunella crassifolia flavonoid was taken orally. The immunodulatory effects were measured by clearance rate K of charcoal particles, phagocytic index a, thymus and spleen index, ear swelling degree, HC50 value and so on.

方法环磷酰胺诱导小鼠免疫功能低下,予金橘黄酮,观察小鼠碳粒廓清指数K、吞噬指数a、胸腺和脾脏指数、耳肿胀度、血清溶血值(HC50)等指标的变化。

Methods:Eightythree patients with galactophore cancer were stochastic divides into observation group and contrast group.

83 例乳腺癌患者,随机分成观察组和对照组。观察组43 例,接受以ADM为主的CAF方案(环磷酰胺+阿霉素+氟尿嘧啶)。

Stability of electrodeposition liquid, the physical and chemical resistance properties of the film depend on amine value, kinds of glycidic ester used, GA content and the amount of blocked polyisocyanate used.

结果表明,环氧基在固化过程中会参与交联反应,电泳液的稳定性、涂膜的物理性能和耐化学品性能由胺值、缩水甘油酯单体种类、丙烯酸缩水甘油酯含量和封闭型多异氰酸酯用量等因素决定。

The glucose, as raw material, underwent glycuronic inner ester 109, cyclohexanone 113 and amination reduction important process to afford the target product in 13 steps.

本文通过大量的摸索和实验,由葡萄糖出发经过制备葡萄糖内酯109、制备环己酮113及还原胺化总计13步反应以总收率25.3%制备得到伏格列波糖。

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