环胺

Our results are complementary to the earlier work by Law and co-workers. The photosensitivity is enhanced for the pigments with larger anilide ring.

首次考察了偶合基酰胺芳环共轭环扩大时光敏性的变化规律，发现酰胺芳环共轭环扩大时有所提高。

Mainly engaged in: Hydrogen-imide hydrochloride, o-chlorophenyl cyclopentanone, 3.4 dimethoxy ethyl benzene, butyn single potassium acid, potassium ethyl malonyl, Ding amide, amide isobutyraldehyde , allyl chloroacetate, isopropyl chloroacetate Benzyl aluminum, cyclopentene, cyanide-o-chlorophenyl, o-methyl chloride, sulfuric acid chloride, p-chlorophenol, imidazole, Pinacolone, one chlorine Pinacolone.

主要经营：盐酸氢亚胺、邻氯苯基环戊酮、3.4二甲氧基苯乙酯、丁炔二酸单钾盐、丙二酸单乙酯钾盐、丁酰胺、异丁酰胺、氯乙酸烯丙酯、氯乙酸苄酯异丙醇铝、环戊烯、邻氯苯氰、邻氯苯甲酯氯、硫酸氯、对氯苯酚、咪唑、频呐酮、一氯频呐酮。

This structure is unstable,and the proton is transferred from C6 to the sulfone to yield the bicyclic end product.

烯胺反应物也可先通过噻唑环内的氢迁移得到亚胺式反应物，从而得到亚胺式双环产物。

This work, concentrated on the asymmetric allylation of aldehydes controlled by different chiral auxiliaries prepared from rotational pure tartaric acid, can be divided into three parts.The first part aims to review the developments of chiral drugs and asymmetric synthesis, from which derived the present research topic backgrounds and works.Synthesis and applications of allylation from aldehydes are the second part of the thesis. By optimizing the reaction conditions, such as solvents, temperature, time and chiral auxiliaries like N,N\'-dibenzyl tartamide, N,N\'-p-dimethylphenyl tartamide, N,N\'-o-dimethylphenyl tartamide, N,N\'-o-dichlorophenyl tartamide, N,N\'-a-dinaphyl tartamide, N,N\'-dicyclohexyl tartamide and N,N\'-diphenyl tartamide, ideal experimenttal conditions are obtained according to HPLC monitoring, as well as the auxiliaries\' recoveries experiments. Starting from benzaldehyde and 3-bromopropaldehyde, N,N\'-dibenzyl tartamide is considered the best auxiliary in this reaction.

本文介绍了醛的不对称烯丙基化反应，以光学纯酒石酸为原料，研究了不同构型手性配体在醛的烯丙基化反应中的立体选择性，全文共分三部分十个章节：第一部分对当前手性药物和手性技术进行了概述，并由此展开了本文的研究背景和任务；第二部分为有机合成部分，对醛的不对称烯丙基化反应进行了深入探讨，以苯甲醛为原料对反应条件进行优化，在优化的反应条件下对制备的七种可回收手性酰胺配体(N-苄基酒石酸二酰胺、N-对甲苯基酒石酸二酰胺、N-邻甲苯基酒石酸二酰胺、N-邻氯苯基酒石酸二酰胺、N-a-萘基酒石酸二酰胺、N-环己基酒石酸二酰胺和N-苯基酒石酸二酰胺)进行筛选，优化配体回收实验条件，最终确定出N-苄基酒石酸二酰胺在苯甲醛的不对称烯丙基化反应中具有较大优越性，结晶回收的手性配体光学纯度保持不变。

This dissertation is mainly focused on the reactivity of methylenecyclopropanes and comprises six parts. 1 The reactions of methylenecyclopropanes with phenylsulfenyl chloride, phenylselenyl chloride and diphenyl diselenide; 2 The coupling reactions of the ring-opening products derivated from methylenecyclopropanes; 3 The palladium-catalyzed ring-enlargement of mono-aryl group substituted methylenecyclopropanes to cyclobutenes. 4 The gold-catalyzed domino ring-opening and ring-closing hydroamination of methylenecyclopropanes with sulfonamides; 5 The Lewis acid-catalyzed reactions of mono-aryl group substituted methylenecyclopropanes with diethyl ketomalonate in the presence of water; 6 The iodobenzene diacetate mediated novel 1,3-dipolar cycloaddition of methylenecyclopropanes, vinylidenecyclopropanes, and methylenecyclobutane with phthalhydrazine.

本论文主要研究了亚甲基环丙烷类化合物的一些化学反应性能，共由以下六部分组成：1、亚甲基环丙烷类化合物与苯硫氯、苯硒氯及二苯基二硒的反应；2、亚甲基环丙烷类化合物开环产物的偶联反应；3、单芳基取代的亚甲基环丙烷类化合物在钯催化剂作用下的扩环反应；4、金化合物催化磺酰胺对亚甲基环丙烷类化合物的串联开环关环氨氢化反应；5、路易斯酸催化亚甲基环丙烷类化合物与丙酮二羧酸二乙酯在有水存在下的反应；6、醋酸碘苯促进的亚甲基环丙烷类化合物、亚乙烯基环丙烷类化合物及亚甲基环丁烷类化合物与邻苯二甲酰肼的新型1，3-偶极环加成反应。

An unreported compound 2-cyclopropylbenzimidazolium salt was obtained from 2-cyclopropyl benzimidazole and iodomethane.

以邻苯二胺和环丙基甲酸为原料，以多聚磷酸为催化剂，在微波辐射下合成了环丙基苯并咪唑，用碘甲烷季胺化得到未见文献报道的环丙基苯并咪唑盐，通过苯并咪唑盐与Grignard试剂加成后水解反应制备环丙基甲基酮。

Results: The extract of propolis had certain antineoplasm effect and the inhibition rate of propolis extract on tumor is 27.74％ and when combined with cyclophosphamide, the inhibition rate reached to 50.32％, even antagonized leucocytopenia caused by cyclophosphamide.

结果：蜂胶提取物的抑瘤率为27.74％，与环磷酰胺合用的抑瘤率为50.32％，比单用蜂胶提取物及环磷酰胺分别提高22.58％和9.03％(P＜0.05)，并能减轻环磷酰胺所致的骨髓造血功能抑制，使血液白细胞维持在正常水平(P＜0.01)。

The synthetic route starts from penicillin G, peroxyacetic acid(8.5%) as Oxidizing Agent to get penicillin G sulfoxide; esterifided with p-nitrobenzyl bromine to synthesize penicillin G sulfoxide ester; we synthesize 3-exomethylenecepham sulfoxide ester with phthalimide potassium and 4A molecular sieve as acid scavenger to open the ring, SnCl_4 as catalyzation to close the ring. The yield is over 60%.

本研究采用的合成路线为：以青霉素G钾盐为原料，选用工业过氧化氢制备的过氧乙酸(22.3%)稀释至8.5%为氧化剂，氧化得青霉素亚砜；采用对硝基溴苄为酯化试剂，制备青霉素亚砜酯；以NCP(N-氯代邻苯二甲酰亚胺)为开环试剂，酞酰亚胺钾和4A型分子筛为酸清除剂，顺利开环；再经无水SnCl_4催化闭环得3-环外亚甲基头孢亚砜酯，最终产率在60%以上。

New reactions found in this program include: photoinduced regioselective free radical addition to aromatic imines;photoinduced Dielse-Alder reactions of aromatic imines for synthesis of tetrahydroquinoline derivatives;Photoinduced radical cation mediated selective ring opening reaction of epoxides;Formation of novel macrocyclic crown ethers by photoinduced reaction of diazonaphthaquinones;photoinduced selective desilylation of silyl ethers.

用这种方法成功的发现了下列在有机合成中有意义的新反应：(1)光诱导产生的自由基正离子诱导的自由基对芳香亚胺的区域选择性加成反应；(2)用光诱导的芳香亚胺的Diels-Alder反应合成四氢喹啉衍生物；(3)经光诱导产生的自由基正离子基诱导的环氧化物选择性开环反应；（4）重氮萘酮在环醚中经光诱导反应形成新奇的大环冠醚；（5）硅醚的光诱导选择性脱硅基反应。

Methods 80 normal BALB/c mice were distributed randomly into 10 groups. The medulla haematogenous effect was compared among the normal group, the irradiation group, the injection cyclophosphamide group, the irradiation and injection cyclophosphamide combation group and the irradiation, cyclophosphamide and chloramphenicol combation group.

本实验采用BALB小鼠80只，分10组，每组8只，通过正常组、单纯照射组、单纯环磷酰胺注射组、照射加环磷酰胺注射组和照射加环磷酰胺加氯霉素注射组等复合造模比较骨髓造血情况。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失