环甲的

Using cobalt chloride and ferromanganese as precursor of cobalt-based catalyst, the performance of the catalyst for hydroformylation of cyclohexene was studied.

以氯化钴和锰铁合金粉为钴基催化体系的前驱体，研究了该催化剂体系对环己烯氢甲酰化反应制备环己烷基甲醛的催化性能；并考察了溶剂、温度、压力等反应条件的影响。

According to the synthetic methods study of the quinolones, it is found that the synthetic method of parent ring is of wide use by the condensation from α-substituted aryl formyl-β-substituted aminoacrylic acid and the inner molecular nucleophilic substitution reaction, which is almost suitable for the quinolones preparation of different rings or different substituted groups in 〓-position.

然后，对其合成方法进行了归纳，发现：由α-取代芳甲酰基-β-取代氨基丙烯酸缩合，经分子内亲核取代反应形成喹诺酮母环的合成方法用途非常广，几乎适用于所有不同环系或〓-位是不同取代基的喹诺酮类衍生物的制备。

The performance of these catalysts was similar to that in their methoxycarbonylation of pyrrole, suggesting that the catalyst system obeyed the same mechanism in the methoxycarbonylation of heterocyclic compounds.

这些催化剂的性能和反应规律类似于吡咯的甲氧基羰基化反应，意味着在杂环的甲氧基羰基化反应中，催化体系具有相近的反应机理，这有待于进一步的研究。

By using the a device being similar to water segregator and by controlling the temperature, cyclization of the intermediate product in chloroform reduced carbonization and gave 2-dodecaneanthraquinane in 68.1% yielding.

以十二烷基苯和苯酐为起始原料，经酰基化、关环和磺化三步反应合成了3-十二烷基蒽醌磺酸；并进一步改进和优化了合成工艺条件：即在催化剂三氯化铝过量50%并有三乙胺存在的条件下，中间体2-（4-十二烷基苯甲酰基）苯甲酸收率为72.45%；关环反应采用氯仿作溶剂，利用类似分水器的装置有效控制反应温度以减少碳化，2-十二烷基蒽醌的收率为68.1%。

The analysis of SAR reveals that the activities of target compounds are closely associated with the electron-withdrawing substituents at the para position of 1-aryl-1, 2, 4 -triazoles as well as with the substituents such as sulfonyl and methylthio groups at the 3 position of 1, 2, 4 -triazoles; And the introduction of sulfamoyl moiety at the para position of 5-aryl-1,2,4-triazoles also has significant influence on the anti-inflammatory activity of these compounds.

构效关系分析发现，在三唑环1位芳基的对位引入F、Cl、Br吸电子基团以及3位引入磺酰基和甲硫基，对抗炎活性有重要的意义；在三唑环5位芳基的对位引入氨磺酰基，对抗炎活性有较大影响。

In the process of laboratory study, oxycodone was prepared by oxidating thebaine at 6,14-position under oxydol, hydrodeoxidizing 7,8-position double bond and 14-position ether under palladium catalyst. Furthermore, N-methyl of oxycodone was isolated byα-chloro-ethyl chloroformate under anhydrous condition and protection of 14-position hydroxyl to obtain noroxycodone, which was further converted into methylnaltrexone by N-alkylation in presence of cyclopropyl bromomethane, then by isolating 3-position methyl of methylnaltrexone under boron tribromide, becoming hydrochloride to prepare target compound, natrexone hydrochloride.

实验室工艺方面，本文首先用双氧水氧化蒂巴因的6-位和14-位、在钯炭催化下加氢还原7-8位双键和14-位醚合成羟考酮，然后提出并优化了在无水和14-位保护的情况下，用氯甲酸-α-氯乙酯脱去羟考酮的N-位甲基合成去甲羟考酮，再用环丙甲基溴将去甲羟考酮的N-位烷基化合成甲基纳曲酮，最后采用三溴化硼脱去甲基纳曲酮的3-位甲基和成盐酸盐合成盐酸纳曲酮。

METHODS: Based on the antitumor activity and structural feature of 8-chloroadenosine and retinoic acid, modifications were made at positions 5′ and 8,substituted cinnamoyl and benzoyl groups were bound at 8 position through amido and ester bonds, sulfonation and nitrosation at 5′-OH and its direct chlorination were conducted.

对腺苷的8位和8-Cl-腺苷的糖环羟基进行了结构改造，以酰胺键和酯键在腺苷的8位连接了具共轭基团的肉桂酰基和苯甲酰基，得到腺苷的维甲类似物；对8-Cl-腺苷的5′-羟基进行了甲磺酰化，硝基化以及氯代反应，得到了它的衍生物。

In this thesis, two series compounds of thiadiazole (2a~2f) and benzothiazole (5a~5f) were synthesized by using the reagent of iodobenzene diacetate. We also bound the iodobenzene diacetate reagent to the resin and applied it to synthesize thiadiazole and benzothiazole compounds.

本文利用二醋酸碘苯试剂分别与1-芳甲酰基-5-芳基-2-硫代缩二脲及1-芳甲酰基-3-芳基硫脲反应合成了噻二唑(2a~2f)和苯并噻唑(5a~5i)两个系列的杂环衍生物，并通过把二醋酸碘苯负载在高分子上合成了一类新型的固相氧化剂，同时考查了该固相氧化剂在噻二唑，苯并噻唑类化合物合成中的应用以及该固相氧化剂的循环使用。

Three series of segmented polyurethanes were synthesized, which are based on 4,4'-methylene-di, N-methyl diethanolamine and hydroxy terminated poly-butadiene, poly or poly.

本文讨论了以聚环氧乙烷、聚环氧丙烷以及聚丁二烯为软段，以4，4'-二异氰酸二苯甲烷和N，N-二羟乙基甲胺为硬段的链段型聚氨酯的合成。

This protocol could also be used for the selective reduction of the endocyclic double bond of the 3-electron withdrawing group substituted coumarins. This method is clean, mild, and efficient.2 ZrCl_4 / HEH was found to be a selective and efficient reagent combination for the direct reductive amination of electron rich aldehydes and ketones with weakly basic amines after scanning various catalysts such as InCl_3, BiCl_3, CF_3COOH and so on.

图一 1。我们用汉斯酯作为有机还原剂，乙醇为溶剂，实现了4-甲叉基噁嗯唑酮和吡唑酮环外双键的高选择性还原；此外，我们还将这一还原体系用于3-吸电子集团取代-3，4-二氢香豆素环内双键的选择性还原。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了