环二脲

For the synthesis of NHC precursors, there are also several routes: condensation of glyoxal, amines and paraformaldehyde; alkylation of imidazole or monosubstituted imidazole with alkyl halide; annulation of ortho esters and 1,2-diamines; ring closure of hydrazines or amides with acetic anhydride; reduction of thiones with Na/K in THF.

关于N-杂环卡宾前体的合成途径主要有：乙二醛、伯胺和多聚甲醛的缩合反应；卤代烷与咪唑及其取代咪唑的烷基化反应；原甲酸酯与1，2-二胺的成环反应；肼或酰胺与酸酐的环化反应；用Na/K对环硫脲化合物的还原反应。

In order to find high active pesticide containing heterocycle, six novel terephthaloyl bisthioureas containing 1, 3, 4-thiodiazole were synthesized by the reaction of 2-amino-5-alkyl-1, 3, 4-thiodiazoles with terephthaloyl diisothiocyanate.

摘 要：为寻找高活性的含杂环农药，由中间体5-烷基-2-氨基-1， 3， 4-噻二唑与对苯二甲酰基二异硫氰酸酯反应，合成6种新的含1， 3， 4-噻二唑环的对苯二甲酰基双硫脲化合物Ⅲaf。

Benzyloxy benzoyldimethylsulfoxide was prepared by the reaction of ethyl 4-benzyloxybenzoate and dimethyl sulfoxide in the presence of sodium hydride, followed by Pummerer reaction with concentrated hydrochloric acid to afford eo-hydroxy-co-thio-methyl-(4/-benzyloxy) acetophenone, which reacted with urea, thiosemicarbazide, semicarbazide hydrochloride and o-phenylenediamine to give imidazolidine-2,4-dione, l,2,4-triazine-3- one and quinoxaline derivatives, respectively.

本文用4-苄氧基苯甲酸乙酯和二甲亚砜为原料，在氢化钠存在下反应，合成了(4′-苄氧基)-苯甲酰基-二甲亚砜。研究了该亚砜在浓盐酸的存在下发生的Pummerer重排反应，用重排产物ω-羟基-ω-甲硫基-(4′-苄氧基)-苯乙酮分别与尿素、氨基脲、氨基硫脲和邻苯二胺反应合成了2，4-咪唑啉-二酮、1，2，4-三嗪-3-酮、喹喔啉等含氮杂环化合物。

In this thesis, two series compounds of thiadiazole (2a~2f) and benzothiazole (5a~5f) were synthesized by using the reagent of iodobenzene diacetate. We also bound the iodobenzene diacetate reagent to the resin and applied it to synthesize thiadiazole and benzothiazole compounds.

本文利用二醋酸碘苯试剂分别与1-芳甲酰基-5-芳基-2-硫代缩二脲及1-芳甲酰基-3-芳基硫脲反应合成了噻二唑(2a~2f)和苯并噻唑(5a~5i)两个系列的杂环衍生物，并通过把二醋酸碘苯负载在高分子上合成了一类新型的固相氧化剂，同时考查了该固相氧化剂在噻二唑，苯并噻唑类化合物合成中的应用以及该固相氧化剂的循环使用。

Our company supply raw materials and related intermediates as follows: Second dibutyryl cAMP calcium, voriconazole, terbinafine, vecuronium amines, cAMP, thiamphenicol, a chlorophenol hydrochloride esters, card network sodium phosphate tilmicosin, foscarnet, lornoxicam, Tilmicosin, Cephalosporium aspirin acid, ceftiofur hydrochloride, ceftiofur sodium, Ozagrel, ondansetron hydrochloride ketones, hydroxyurea, ticarcillin sodium, telmisartan, esmolol hydrochloride, hydrochloric acid Daguan Nikkomycin, adefovir dipivoxil, buflomedil hydrochloride, granisetron hydrochloride, warfarin sodium,-methyl gabexate acid, nicergoline, pantoprazole sodium,·, tegafur, cefepime hydrochloride, vecuronium bromide, hydrochloric acid meclofenoxate, sertraline hydrochloride, Cefonicid amine salt, aztreonam, ticarcillin, cefdinir, cefodizime sodium, sodium ferulate, colloidal pectin secretion, 2,3 - cyclopentene and pyridine, Piperacillin acid, cefetamet US-acid, hydrochloride Cefmenoxime ,3-TZ, 2 - deoxy-D-glucose, two-amidine urea benzene, sodium Cefonicid, Cefonicid intermediates, ester Cefamandole sodium, Cefalotin acid, intermediates cefpirome, cefepime sulphate, cefepime intermediate nucleus of cefepime, cefpirome nucleus, Cefamandole sodium, ceftriaxone new active ester, oxaliplatin, cyclophosphamide vary gland amines, polyene match him.

我公司供应的原料药及相关中间体为：二丁酰环磷腺苷钙、伏立康唑、盐酸特比萘芬、维库溴胺、环磷腺苷、甲砜霉素、盐酸甲氯酚酯、卡络磺钠、磷酸替米考星、膦甲酸钠、氯诺昔康、替米考星、头孢匹胺酸、头孢噻呋盐酸盐、头孢噻呋钠、奥扎格雷、盐酸恩丹西酮、羟基脲、替卡西林钠、替米沙坦、盐酸艾司洛尔、盐酸大观霉素、阿德福韦酯、盐酸丁咯地尔、盐酸格拉司琼、华法林钠、甲磺酸加贝酯、尼麦角林、泮托拉唑钠、普拉洛芬、替加氟、盐酸头孢吡肟、维库溴铵、盐酸甲氯芬酯、盐酸舍曲林、头孢尼西胺盐、氨曲南、替卡西林、头孢地尼、头孢地嗪钠、阿魏酸钠、胶体果胶泌、2，3-环戊烯并吡啶、哌拉西林酸、头孢他美酸、头孢甲肟盐酸盐、3-TZ、2-脱氧-D-葡萄糖、双脒苯脲、头孢尼西钠、头孢尼西中间体、头孢孟多酯钠、头孢噻吩酸、头孢匹罗中间体、头孢吡肟硫酸盐、头孢吡肟中间体、头孢吡肟母核、头孢匹罗母核、头孢孟多钠、头孢曲松新型活性酯、奥沙利铂、异环磷腺胺，多烯他赛。

A series of 2-oxocyclododecyl sulfonylurea s have been synthesized from 2-oxocyclododecylsulfonamide via acylation of phenyl chloroformate and amination.

以环十二酮为起始原料，经磺化反应制备得到2-氧代环十二烷基磺酸盐B，B经过氯化和胺解反应制备得到2-氧代环十二烷基磺酰胺C，C经过苯氧酰化与胺解反应后合成了10个新的2-氧代环十二烷基磺酰脲类化合物D，它们的结构通过了1HNMR和IR的确证。

Five novel asymmetrical molecular tweezers based on diethoxycarbonyl-and diphenyl glycoluril with different substituted groups of aromatic ringsand 1,2 -dihydro-indazol-3-one moiety as sidewalls were designed and synthesized.

合成了五个含单个1，2-二氢-引唑-3-酮和不同取代的苯环(H，OMe，Me，Br)为墙面的基于二乙基酯基甘脲和二苯基甘脲的不对称分子钳。

On the basis of these principles and requirements,in this paper,a new modifier has been synthesized from pyromellitic dianhydride and thiosemicarbazide by the nucleophilic addition of anhydride,the cyclization of acyl thiosemicarbazide in alkaline solution,and the N-hydroxymethylation of the triazole-thione.

本文根据这一思路，以均苯四甲酸二酐和氨基硫脲为起始原料，通过酸酐的亲核加成反应、酰氨基硫脲的碱性环化反应、三唑硫酮环的N-羟甲基化反应合成出了一种新的N-羟甲基三唑硫酮酸改性剂。

The title compounds were synthesized by the reaction of symmetric N , N '-diarylthioureas with hexylamine in the presence of triethyl amine,and the intermediate N , N '-diarylthioureas were formed by the direct reaction of carbon disulfide and arylamines.

首先采用二硫化碳与胺直接反应得到对称的N， N'-二芳基硫脲，然后在三乙胺存在下与环己胺反应得到1-环己基-3-芳基硫脲。产物结构经核磁共振和质谱分析确证

Firstly, phenyliodine diacetate was immobilized to the 2% cross-linked polystyrene or the liner polystyrene resin. The more iodine the resin had, the lower conversion to phenyliodine diacetate. We made our endeavor to extend the range of useful application of polystyrene supported phenyliodine diacetate in organic synthesis:(1) the reagent was used as an effective reagent of carbonyl regeneration from oximes and semicarbazones of ketones.(2) the reagent was also applied to the synthesis of 1, 3, 4-oxadiazoles, 1, 3-disubstituted-2-pyrazoline, 2-arylbenzoxazole from aldehyde N-acylhydrazones, aldehyde hydoazones and phenolic Schiff's bases respectively.

首先，我们以2％交联的聚苯乙烯和线性的聚苯乙烯树脂为载体，制备了聚合物负载的二醋酸碘苯，通过研究发现：(1)聚苯乙烯二醋酸碘苯是酮肟、缩氨脲有效的去保护试剂，不仅芳香酮，脂肪酮和α，β不饱和酮的肟、缩氨脲也能顺利转化为相应的酮，实现酮基的再生；(2)我们还利用此试剂，分别与醛的N-酰基苯、N-酰基苯腙及邻羟基芳亚胺反应，在温和的条件下发生成环反应，以良好的产率生成1，3，4-噁二唑、吡唑啉和二取代苯并噁唑等杂环化合物；(3)聚苯乙烯二醋酸碘苯还可有效地将邻羟基芳酮的酰腙经氧化、重排成1，2-二酰基苯。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。