环

Keywords: Organozinc reagents; cis-Addition Products; Ring-expansion; Chain-extension

中文关键词：有机锌试剂；环氧的顺式开环；酮酯的扩环；碳链增长

Organozinc reagents; cis-Addition Products; Ring-expansion; Chain-extension

中文主题词：有机锌试剂；环氧的顺式开环；酮酯的扩环；碳链增长

Yet, completely differ from the cases of 〓-H, the 〓-dihydroxyl group was introduced after subsequent epoxidation and oxane ring opening of the 〓 tricyclic olefin.

在〓-β-H三环烯31基础上的环氧化和环氧开环反应引入的两个羟基，为双直立的〓，不同于〓类。

The time to peak systolic longitudinal strain and the time to peak systolic radial strain were derived from the LV apical views , and to peak systolic circumferential strain was derived from the parasternal short axis. The standard deviation for time to peak longitudinal、circumferential and radial strain in the 18 segments (LS-SD18、CS-SD18、RS-SD18) and the maximal temporal difference of any two segments(LS-dif、CS-dif、RS-dif)were calculated as a strain-derived dyssynchrony index.

方法16例慢性心衰患者，获取心尖长轴观测量各节段收缩期纵向应变达峰时间，径向应变达峰时间，胸骨旁短轴观测环向应变达峰时间，计算CRT术后1个月、术后3个月18节段纵向、环向、径向应变达峰时间标准差(LS-SD18、CS-SD18、RS-SD18)、左室各节段收缩期纵向、环向、径向应变达峰时间最大差值(LS-dif、CS-dif、RS-dif)作为应变非同步指标。

Cycloserine was produced using L-serine methyl ester hydrochloride as raw material. L-serine methyl ester hydrochloride was chloridized with phosphorus pentachloride to afford 2-amino-3-chloride propanic acid methyl ester hydrochloride, which was cyclized with hydroxylamine in the presence of alkali to give cycloserine.

以L-丝氨酸甲酯盐酸盐为原料制备了环丝氨酸。L-丝氨酸甲酯盐酸盐和五氯化磷在氯仿溶剂中进行氯代反应生成2-氨基-3-氯丙氨酸甲酯盐酸盐，后者和羟胺在碱性溶液中发生环合反应得到环丝氨酸。

The fact that the compound, 2-methyl-2-di- methylaminomethyl-5--n-pentylidenecyclo- pentanone hydrochloride (T60) possessed little anticancer activity indicated that the Mannich bases that could formed a methylene group were necessary for anticancer activity.

当环戊酮环上的Mannich碱侧链位置上引入取代基时，抗癌活性显著降低，如化合物2-甲基-2-二甲胺甲基-5--亚戊基环戊酮盐酸盐（T60）几乎无抗癌活性。这说明Mannich碱能形成亚甲基是这类化合物产生抗癌活性所必不可少的条件。

To discover new strobilurin analogues with high pesticidal activity, a series of new strobilurin derivatives containing substituted pyrazole and pyrimide ring, which included 124 novel compounds (73 compounds containing substituted pyrazole ring and 51 compounds containing substituted pyrimide ring) were designed and synthesized. In addition, 36 new intermediates were synthesized. Their structures were characterized by ~1H NMR and elemental analysis, partial compounds were characterized by MS and IR once again.

为了发现具有更好生物活性的新型Strobilurin类化合物，本论文在详尽总结文献的基础上，设计并合成了含吡唑和嘧啶环的新型Strobilurin类化合物124个，其中含吡唑环的新型Strobilurin类化合物73个，含嘧啶环的新型Strobilurin类化合物51个；未见文献报道的中间体36个，所合成的化合物经过~1H NMR、IR、LC-MS或元素分析等确定了结构。

To discover new strobilurin analogues with high pesticidal activity, a series of new strobilurin derivatives containing substituted pyrazole and pyrimide ring, which included 124 novel compounds (73 compounds containing substituted pyrazole ring and 51 compounds containing substituted pyrimide ring) were designed and synthesized. In addition, 36 new intermediates were synthesized. Their structures were characterized by 1H NMR and elemental analysis, partial compounds were characterized by MS and IR once again.

为了发现具有更好生物活性的新型Strobilurin类化合物，本论文在详尽总结文献的基础上，设计并合成了含吡唑和嘧啶环的新型Strobilurin类化合物124个，其中含吡唑环的新加热管型Strobilurin类化合物73个，含嘧啶环的新型Strob 加热管 ilurin类化合物51个；未见文献报道的中间体36个，所合成的化合物经过1H NMR、IR、LC-MS或元素分析等确定了结构。

The C_(60)-fused tetrahydrofuran derivatives are excellent synthons for further functionalization.While treated with different equiv,of BF_3·OEt_2 at various temperature,several novel functionized fullerene derivatives have been successfully synthesized.2.1,4-Fullerenols C_(60)ArOH were synthesized via the reaction of[60]fullerene with 4-substituted phenylhydrazine hydrochlorides and sodium nitrite under moisture and aerobic conditions.

这种四氢呋喃环合富勒烯衍生物作为一个合成中间体又可发生进一步的衍生化反应，其与不同当量BF_3·OEt_2在不同温度条件下可以得到二氢呋喃环合富勒烯衍生物、三元环合富勒烯衍生物等。2。

Using cyclohexanol as raw material, in presence of sodium tungstate and phosphotungstic acid as catalyst, the technique for oxidizing cyclohexanol to cyclohexanone with hydrogen peroxide were discussed.

以环己醇为原料、钨酸钠和磷钨酸配合为催化剂，探讨了双氧水为氧化剂氧化环己醇合成环己酮的工艺方法。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。