然后

Synthesis of target compounds namely: to vanillic acid as the starting material with methanol under reflux conditions for 4 - hydroxy -3 - p-methyl, then ether, and nitration, reduction, cyclization reaction 6 - methoxy -7 - benzyloxy-quinazoline -4 - one, and then by the chloride in place of aniline, benzyloxy-off, such as etherification reaction of the target compounds; target compounds with the second and third occurrence of substitution reactions of amines by the TM1, that is, 4 - amino-benzene -6 - methoxy -7 - [2 - hydroxy -3 -(N, N-diethyl amino) oxy c] quinazoline; with ether occurred Ornidazole reaction of TM2, namely, 4 - amino-benzene -6 - methoxy -7 - [2 - hydroxy -3 -(2 - methyl -5 - nitroimidazole) C oxy] quinazoline.

本论文以嘌呤类似物喹唑啉为母核，分别在其4位和7位引入结构多样的取代苯氨基和柔性侧链，设计了一系列4-取代苯胺基-6-甲氧基-7-(2-羟基取代丙氧基)喹唑啉类化合物。目标化合物的合成即：以香草酸为起始原料，与甲醇回流条件下得到4-羟基-3-甲氧基苯甲酸甲酯，然后经过醚化、硝化、还原、环合反应得到6-甲氧基-7-苄氧基喹唑啉-4-酮，然后再经氯化、取代苯胺、脱苄氧基、醚化等反应得到目标化合物；目标化合物与二乙胺发生胺取代反应得到了TM1，即4-苯氨基-6-甲氧基-7-[2-羟基-3-丙氧基]喹唑啉；通过与奥硝唑发生醚化反应得到TM2，即4-苯氨基-6-甲氧基-7-[2-羟基-3-(2-甲基-5-硝基咪唑)丙氧基]喹唑啉。

Somewhere up in the attic is a brown, medium-size Samsonite suitcase that was a Christmas present in 1981. It served me ably all during my years as a traveling college textbook salesman, spending more nights in La Quinta Motor Inns than I care to remember.The reason I bring up that hard-cased suitcase is that the same item appears in "The Pursuit of Happyness," which opened this past Friday. I'm sure the prop department found one on eBay or at a garage sale.

刚刚看完了《the pursuit of happiness 》心理真的是感慨万千，里面有的话特别好，小男孩在打篮球的时候，他爸爸说他小的时候，篮球打得很烂，然后说小男孩的水平也不可能很好，然后小男孩很气馁，他爸爸说：hey ，you have a dream ，and you should protect it.never let people tell you ，you cannot do anything，because they can not do it ，so they tell you cannot do it。

143 Chapter 1 The History and Future of Computers 3.1.6 Complements To form the radix complement, first find the radix -1 complement, and then add a one to the result.

为得到补码，先求反码，然后将加到结果上加到结果上。为得到补码，先求反码，然后将1加到结果上。

24 Chapter 3 Number Systems and Boolean Algebra 3.1.6 Complements To form the radix complement, first find the radix -1 complement, and then add a one to the result.

为得到补码，先求反码，然后将加到结果上加到结果上。为得到补码，先求反码，然后将1加到结果上。

I had a random girl walk past me at a restaurant, and then she turned, ran up to me, told me "I love you," she kissed me, and then she ran away.

有一次，一个姑娘在一家餐馆前走过我身边，然后她转过身向我跑来，跟我说'我爱你，'她亲了我，然后跑掉了。

In fact, I think I'm ready to rappel down and go to the hot tub.

事实上，我想我已准备好垂降，然后然后回去泡个热水澡。

If I cancel my account for a month and then reactivate it, will I be able to play then?

如果我取消我的一月而且然后解释使恢复现役它，我将会可以吗然后玩？

Put cavalry on the side of the battlefield and order them to attack the rearmost enemies. During combat they will try to outflank the enemy and attack his rear troops and commanders.

把你的骑兵放在队伍侧翼，然后为其下达"攻击最远敌人"的命令，他们就会在战斗中试图从侧翼绕过敌人然后包抄攻击对方的后方。

Water enters at the bottom of the tank, and is skimmed from the surface, where it is directed to drain or to a recycler for reuse.

水进入到槽的底部，然后从表面上撇除，然后直通排水管或者再循环器。

Then there was Hubert Johnson taking time off from his job as a redcap at Piarco airport to be Jack's personal assistant.

然后，毛琳沃纳女士要求"请为我的两个儿子再多安排两个房间"，再然后，休伯特约翰逊，从皮亚尔科机场宪兵摇身一变成了沃纳的私人助理。

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷