烯化

E. 3-allyloxyisothiazole and N-allylisothiazolone, were synthesized with 3-mercaptopropionate as the starting material through ammonolysis, cyclization and allylation reactions.

以3-巯基丙酸甲酯为原料，经氨解、关环、烯丙基化合成了2种含有不饱和侧链的异噻唑类化合物，分别为3-烯丙氧基异噻唑和N-烯丙基异噻唑啉酮。

Seven of them have not been reported.Their structures were confirmed by IR,~1HNMR,MS,and element analysis. 4.Meanwhile,the green methylation procedure of imides was developed by using dimethyl carbonate as methylation reagent.A series of imides,for example,phthalimide,3,4-dibromo-maleimide and succincide were used for substrates.The effects of DABCO(1,4-diazabicyclo [2.2.2]octane)and DBU(1,8-diazabicyclo[5.4.0]undec-7-ene)as a catalyst in this kind of reactions were investigated.2-Bromo-3-(1-methylindolyl-3-yl)-1-methyl-1H-pyrrole-2,5-dione was prepared by using dimethyl carbonate,which further expanded the use of dimethyl carbonate,as a green agent in organic synthesis.

在以硫酸二甲酯为甲基化试剂对3，4-二溴马来酰亚胺进行N-甲基化反应合成3，4-二溴-N-甲基马来酰亚胺的同时，以碳酸二甲酯为甲基化试剂，对3，4-二溴马来酰亚胺、邻苯二甲酰亚胺、琥珀酰亚胺等酰亚胺类化合物的N-甲基化反应进行了研究；考察了1，4-二氮杂双环[2.2.2]辛烷，1，8-二氮杂双环[5.4.0]十一碳-7-烯、碳酸钾和四丁基溴化铵等作为催化剂对碳酸二甲酯N-甲基化反应的反应时间和收率等的影响，并应用碳酸二甲酯为甲基化试剂，合成了N-甲基-3-溴-4-(1-甲基-吲哚-3)-马来酰亚胺。

At last,a convergent and general protocol to marine natural product,as demonstrated by the enantioselective total synthesis of malyngamides O,P,Q,R, 5"-epi-Q and 5"-epi-R bearing terminal vinylic chloride structure,was developed in detail.E,(7S)-7-methoxytetradec-4-enoic acid was prepared using the above described Johnson-Clainsen rearrangement,the terminal vinyl chloride was constructed using Wittig reaction as key step,the pyrrolidone derivative was constructed using L-serine as natural chiral pool.Starting from the synthesis of malyngamides O and P to explore the general route,an aldol reaction of methyl acetate with the vinyl chloride part in the presence of LDA gave the skeleton of amine portion,followed by amidation with the fatty acid finished the synthesis of malyngamide P.

先以malyngamides O和P为试点探索通用合成路线，将乙酸甲酯和烯氯部分在LDA存在下进行aldol反应得到氨部分的骨架，再将手性不饱和脂肪酸和氨部分进行酰胺化反应完成了malyngamide P的合成，将P在碱性条件下进行烯醇甲基化反应完成了malyngamide O的全合成。

As superplasticizer , a series of comb-shaped copolymers of polycarboxylic acid were synthesized by polyoxyethylene allyl methyl diether, maleic anhydride, and styrene with different initiators,and esterified with PEO-n.

以聚氧乙烯甲基烯丙基二醚、顺丁烯二酸酐、苯乙烯等为共聚单体，采用不同引发剂，合成了一系列聚羧酸型梳状共聚物超分散剂，并以PEO n单酯化得酯化产物，研究了共聚物的结构、组成、添加量等对水泥粒子分散性能的影响。

These novel reagents were treated with base to produce polystyrene-supported a-seleno carbanions, which reacted with alkyl halides, followed by stereospecific selenoxide syn-elimination to give 2i-vinylphosphonates and is-vinylsulfones respectively.

它们在碱的作用下形成α—硒基碳负离子，然后与卤代烃发生烷基化反应，烷基化后的树脂可以通过温和条件下的氧化消除以良好产率和较高纯度分别合成了烯基磷酸酯和烯基砜。

This novel reagent was treated with LDA to produce polystyrene-supported a-seleno carbanions, which reacted with alkyl halides and epoxides, followed by stereospecific selenoxide syn-elimination to give olefins and allylic alcohols respectively.

它与LDA反应形成α—硒基稳定的碳负离子，再与卤代烃或环氧化合物发生α—烷基化反应，烷基化后的树脂可以在30%的双氧水中进行氧化-消除，以良好产率和较高纯度合成了取代烯烃或烯丙基醇。

Enynes with an aryl ring at the alkyne give 2,3,9,9a-tetrahydro-1H-cyclopentanaphthalenes by a 5-exo-dig cyclization followed by a Friedel-Crafts-type ring expansion.

带有芳环的1，6-二烯体和炔作用，并通过5-exo-dig路径环化，再紧接着Friedel-Crafts扩环，可以得到2，3，9，9a-四羟基-1H-环戊二烯并萘。6-endo-dig途径的环化在一些例子中作为副反应被观察到，尽管，这在一些具体的反应中，是作为主反应出现的。

A novel chiral diallylic diamine has been synthesized through double addition of allyl zinc bromide to chiral imines in this contribution.

通过烯丙基溴化锌对手性亚胺的两次不对称加成，合成了光活性的双烯丙基化的新型手性二胺。

Then, it was condensed with-valine methyl ester to form a chiral imine, which was reacted with allyl zinc bromide in the presence of CeCl3·7H2O to afford the corresponding chiral homoallylic amine with high optical activity.

-N-Boc-3-苯基-2-氨基丙醛与-缬氨基酸甲酯缩合生成手性亚胺，在七水合三氯化铈（CeC13·7H2O）催化以及底物的手性诱导作用下，该手性亚胺与烯丙基溴化锌经不对称加成反应合成了高光活性的单烯丙基化手性胺。

On the basis of the above N-vinylaiton of amides,the Cu-catalyzed intramolecular C-S coupling of thiols was implemented for the first time with CuI (10 mol%) as the catalyst and K_3PO_4·3H_2O2 equiv.

在酰胺氮烯基化研究的基础上，我们进而开展了烷基硫醇分子内烯基化反应研究。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。