热素的

Our process capability: Plates: FR4, High TG FR4, high CTI FR4, high frequency materials, halogen-free materials, aluminum and other low-rise Materials :2-20 layer of finished copper thickness :0.5-5 OZ finished thickness: 0.2 -6.0mm Minimum line width: 3mil Minimum line spacing: 3mil smallest shape tolerances:+/-0.1mm minimum finished diameter: 0.1mm maximum thickness aperture ratio: 12:1 wide minimum solder bridge: 4mil characters minimum line width: 5mil Minimum height of characters: 30mil Solder Mask Color: Green, black, blue, white, yellow, purple characters such as color: white, yellow, black and other surface processes: spray tin, lead-free HASL, Electroless gold plating Shuijin, OSP, chemical Shen tin, silver and other chemicals Shen Process: Goldfinger, blue gum, Blind-via/Buried-via, characteristic impedance control, rigid-flexible combination of reliability testing such as: Open / Short testing, impedance testing, solderability testing, thermal shock testing, metallographic analysis of micro-slice curvature Isoptera: 0.7% flame retardant Level: 94V-0

我们公司的制程能力：板材：FR4、高TG FR4、高CTI FR4、高频材料、无卤素材料、铝基材料等层数：2-20层成品铜厚：0.5-5 OZ成品板厚：0.2-6.0mm最小线宽：3mil最小线间距：3mil最小外形公差：+/-0.1mm最小成品孔径：0.1mm最大板厚孔径比：12：1最小阻焊桥宽：4mil最小字符线宽：5mil最小字符高度：30mil阻焊颜色：绿色、黑色、蓝色、白色、黄色、紫色等字符颜色：白色、黄色、黑色等表面工艺：喷锡，无铅喷锡、化学沉金、电镀水金、OSP、化学沉锡、化学沉银等其它工艺：金手指、蓝胶、盲埋孔、特性阻抗控制、刚柔结合等可靠性测试：开/短路测试、阻抗测试、可焊性测试、热冲击测试、金相微切片分析等翅曲度：≤0.7%阻燃等级：94V-0

Cayenne Pepper Fruit: These fruit derive their spicy heat, as well as extraordinary anti-inflammatory, analgesic, heart-healthy effects, from very high levels of capsaicinoids, the most common form of which is capsaicin.

辣椒果实：这些水果中获得的辣热，具有非凡的抗炎、镇痛、心脏健康的作用。它含有非常高的辣椒素含量，其中最常见的形式是辣椒素。

It can stimulate neurotropic receptor to powerfully motivate Transient Receptor Potential Ion Channels which are the vanguard of Cell Sensory Systems to mediate sensory transduction, responding to temperature, touch,pain, sweet, bitter, taste, osmolarity, pheromones, warmth, heat, cold, stimulus and hypertonicity.

它可以刺激神经受体有力地激发瞬间受体电位离子通道，这是先锋的细胞感觉系统来调解感觉传导，反应温度，触摸，疼痛，甜，苦，味道，渗透压，信息素，暖，热，冷，刺激和肌张力亢进。

Sheep embryo with high-purity,high-quality and high security features to extract the cells from the completion of the injection can be divided into three phases:-Using the most advanced chemical and biological equipment from sheep embryos to extract the liver activity of the protein and remove impurities,heat-sensitive eggs White matter and may result in allergic reactions of various types of risk factors-The adoption of advanced technology to extract the cells separated,thus the effectiveness of different cells,such as chest Gland cells,placental cells,liver cells and so on dozens of different types of-Using the most advanced technology to maintain the freeze-dried cells of live sheep-embryo for the first time the use of only afew hours to keep The cell activity,and now,with the continuous development of science and technology,after the extract ion of the cells have been able to keep to five years.

羊胚胎素具有高纯度、高品质和高安全性的特点，从细胞的提取到针剂的完成可分为三个阶段：-运用最先进的生化磁粉探伤仪，从小羊胚胎的肝脏中提取活性蛋白质，并去除杂质、热敏感蛋白质及可能导致过敏反应的各类危险因子-通过先进的技术对提取的活性细胞进行分离，从而得到具有不同功效的活性细胞，如胸腺细胞、胎盘细胞、肝脏细胞等几十种不同类型-采用目前最先进的冻干技术来保持细胞鲜活性，羊胚胎素在最初使用时只能保持几小时的细胞活性，而如今，随着科学技术的不断发展，提取后的细胞活性已经可以保持到5年。

In addition, effects of weld heat input on microstructure and performance of the weldjoints are analyzed. The test results indicate that by controlling weld heat input about 16kJ/cm and practicingmulti-layer weld process, the coarse austenitic grains in the weld metal and lumpish ferrite in the heat affectedzone can be avoided so that the microstructure and performance of the weld joints can be ensured.

结果表明，采用多道焊焊接工艺，严格控制焊接线能量在16 kJ/cm左右，可以防止T91钢焊缝区奥氏体晶粒粗大，避免在热影响区出现块状铁素体组织，从而保证焊接接头区具有良好的组织性能。

The microstructure evolution, precipitation behavior of carbonitride as microalloying element and its effects on deformation induced ferrite transformation of mild steels with various Nb, V content were investigated on a Gleeble 1500 thermechanical simulator through multi-pass thermo-compression in the temperature range of 820~790℃ to simulate the finish rolling process of plates.

在Gleeble 1500热模拟机上，通过820~790℃温度范围内的多道次热压缩变形模拟了中厚板的精轧工艺，考察了不同铌、钒含量的低碳钢的组织演变过程、微合金元素的碳氮化物的析出行为和对形变诱导铁素体相变的影响。

Based on these previous work, in this research, in order to explore the the molecular mechanism of enhanced tumor cell immunogenicity treated by elemene and mytomycin C compositely, we used murine Hca-F ascitic hepatic carcinoma ( high lymphatic metastasis substrain of H22) as an experimental model to compare the immunoprotective effects on Hca-F cells as well as the mechanism of the effects caused by HSP70-peptide complex purified from untreated tumor cells, EC-TCV and BCG; We studied the mechanism of increased tumor cell membrane HSP expression treated with elemene by the techniques of RT-PCR and immunoelectron microscopy; In order to deeply elucidate the antitumor effects and the molecular mechanism of elemene in increasing tumor cell immunogenicity we analyzed and compared the effects of elemene and heat shock on the gene expressions of tumor cell using gene expression profile chip.

本论文在上述研究成果的基础上，选择小鼠肝癌H22的高淋巴道转移亚系Hca-F为模型，进一步比较了未处理肿瘤细胞来源、榄香烯复合瘤苗来源的和卡介苗来源的HSP70-肽复合物对Hca-F的免疫保护效应、效应机制，探讨榄香烯-丝裂霉素复合处理增强肿瘤细胞免疫原性的分子机制；以Hca-F和人肝癌细胞株HepG〓等为模型研究了榄香烯处理增强肿瘤细胞膜热休克蛋白表达的机制；以HepG〓为模型用表达谱基因芯片研究比较了榄香烯与热休克处理对肿瘤细胞基因表达的影响，从而进一步阐明榄香烯抗肿瘤作用及增强肿瘤细胞免疫原性的分子机制。

METHODS Mice hot-plate, writhing test and mice menalgia model of acute stress blood stasis rat was used to compare therapeutic action of the three preparations RESULTS Both chuanxiong formula granule and decoction pieces standard broth of liquored Chuanxiong formula granule and decoction pieces stand ard broth could prolong pain threshold, extend incubation period caused by acetic acid andoxytocin, reduce writhing frequency, and improve some indexes of hemoreology in acute stress blood stasis rat.

选择热板法、扭体法、痛经模型、急性应激血淤血液流变性等方法，比较川芎配方颗粒及饮片、酒川芎配方颗粒及饮片的主要药理作用。结果川芎配方颗粒与川芎饮片标准汤剂、酒川芎配方颗粒与酒川芎饮片标准汤剂均能延长小鼠热板痛闭值，均能延长醋酸所致扭体反应的小鼠扭体潜伏期并减少扭体次数，均能延长小鼠痛经模型中催产素所致扭体反应的潜伏期并减少扭体次数，均具有改善急性应激血淤大鼠血液流变的作用。

Based on the changes in the spectrum characters of guest molecules producedthrough inclusion complex formation with cyclodextrins, we have carried out two aspects of investigation:First, the mechanisms for the host-guest recognition reactions have been studied, such as the interactions between 3-CD and curcumin, the main constituent of the rhizomes of the plant Curcuma longa, the recognition of p-CD towards rubidate, the effective component of the Chinese traditional medicine madder, and the reactions of p-CD towards the antileprotic drug dapsone and the antiinflammatory drug nabumetone: The formation of supramolecular complex between P-CD and guest molecule has been discussed and verified in virtue of multitudinous means such asultraviolet-visible absorption, fluorescence emission, infrared spectrogram and so on. The influence of addition of linear alcohols on the supramolecular system has been studied and the reason why the noncovalent interactions in the three-component system could result in a decrease in the apparent association constant of the inclusion complex has been revealed.

本论文基于环糊精对被包结客体光谱性质的改变，开展了两大方面的研究：β-环糊精对姜黄属植物根茎主要成分—姜黄素、中药茜草有效成分—茜草双酯、抗麻风药物氨苯砜及抗炎药物萘丁美酮的主-客体识别反应机制研究：借助超分子包合物的紫外吸收光谱、荧光光谱或红外吸收光谱等手段，通过多种方法探讨并验证了超分子包合物的形成；研究了直链醇的加入对超分子体系的影响，揭示了三元体系中非共价相互作用导致超分子包合物表观结合常数降低的原因：对超分子包结反应进行了热动力学研究，探讨了各热动力学参数的变化趋势并从熵焓互补的角度考察了超分子包结过程；通过荧光猝灭实验进一步揭示了水相中β-环糊精增敏客体荧光的本质原因，从而为超分子化学提供新的理论和研究方法。

Methods:(1) Dissoluble PGN and CpG DNA were immobilized onto the surface of biotin cuvette for establishing target. Another effective tracking approach was established by immobilizing Escherichia lipid A F583 onto the surface of Non-derivatised cuvett. The biosensor technology was applied to screen anti-inflammatory TCM targeting on three key molecules.(2) The active compositions were isolated by AB-8 macroreticular resin from lycium bark. After the activities of compositions were evaluated, the most effective compositions was confirmed. In vitro, the affinities of different concentrations composition E binding with PGN, CpG DNA and lipid A were measured separately. The effect of composition E on vigor of RAW264.7 cells were tested by MTT and CCK-8, and its inhibition on TNF-α, which was released from RAW264.7 cells induced by PGN, CpG DNA and LPS, was also tested by ELISA. In vivo, murine sepsis models were made by intravenously heat-killed E.coli and heat-killed S.aureus, then protection of composition E on mice sepsis model were observed.

(1)将PGN及CpG DNA包被于生物素样品池，将lipid A包被于非衍生样品池，分别建立以PGN、CpG DNA及lipid A为靶点的技术平台，对114种抗炎中药水提物进行筛选、评价其活性物质含量，并评估出针对上述三种病原分子均具有较高结合活性的中药；(2)利用生物传感器跟踪检测技术、大孔吸附树脂分离技术，从地骨皮中定向分离与PGN、CpG DNA及lipid A均具有较高亲和力的活性组分；在体外实验中，测定不同浓度活性组分与PGN、CpG DNA及lipid A亲和力；MTT法及CCK-8法检测活性组分对RAW264.7细胞活力的影响；ELISA法检测活性组分对PGN(2μg/ml)、CpG DNA(10μg/ml)及LPS(100ng/ml)刺激小鼠RAW264.7细胞分泌TNF-α的抑制作用；在体内实验中，采用尾静脉注射致死剂量热灭活大肠杆菌和热灭活金黄色葡萄球菌，建立细菌脓毒症小鼠模型，观察活性组分对脓毒症模型小鼠的保护作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。