烟酰胺

Nicotianamine synthase gene has an important function in the Fe-deficiency response of graminaceous monocots, and it catalyzes substance to nicotianamine which plays an important carrier in the internal transport of Fe(superscript 2+) and other divalent metal ions. Nicotianamine can bind with Fe(superscript 2+) to form Fe(superscript 2+)-NA complex and protect plants from toxicity in acidic soil.

烟酰胺合成酶基因在单子叶禾本科的缺铁胁迫应答反应中起着关键作用，它的催化产物烟酰胺是铁及其他二价金属离子在体内吸收和转运的重要载体，且能与Fe(上标 2+)结合形成Fe(上标 2+)-NA复合物，从而使植物在酸性土壤中免受铁毒害。

Stable Vitamin K 3 is synthesized by addition reaction of raw materials of niacinamide, chlorhydric acid and menadione sodium bisulfite at 25℃.

以烟酰胺、盐酸为原料，在 2 5℃反应得烟酰胺盐酸盐溶液，而后与亚硫酸氢钠甲萘醌发生加成反应，反应的物料配比为：n ∶ n ∶ n =1∶1。

The optimization of ferment, preparation of immobilized cells, optimization of bioconversion and extraction of nicotinamide were studied in this paper.

本论文中主要研究烟腈水合酶发酵工艺的优化、固定化细胞的制备、固定化细胞生物转化烟腈生产烟酰胺的工艺优化、烟酰胺的提取工艺。

It can be applied in the treatment of pellagra and used as a vitamin supply for human body.

烟酰胺可用于治疗糙皮病，补充人体所需的维生素；作为饲料添加剂，烟酰胺可提高畜禽的抗病、防病能力，促进畜禽生长。

Methods Morphologic change of cells were observed with fluorescence microscope;MTT assay was used to evaluate survival rates Survival rates of GLC-82 cells;The influence of NA to cell migration was analyzed by scarification test; The percentage changes of apoptosis and the distributional percentage of cell cycle were analyzed with flowcytometry.

荧光显微镜观察细胞形态的变化；MTT 法检测不同浓度烟酰胺培养细胞后细胞的存活率；划痕试验检测不同浓度的烟酰胺对细胞愈合力的影响；流式细胞仪检测细胞周期和凋亡率。

They are, 4 21-amidohydrocortisone Ba1～Ba4, 10 21-amidoprednisolone Bb1～Bb10, 4 21-amidomethylprednisolone Bc1～Bc4, 4 21-amidodexamethasone Bd1～Bd4, 1 21-amidobetamethasone Be1, 1 21-amidoRS Bf1, 1 21-amidocortisone Bg1, 1 21-amidoprednisone Bh1. The amido groups were acetamido, nicotinamido, hemesuccinamido, benzoylamido, methanesufonamido, or arylsufonylamido.

包括：4个21-酰胺基氢化可的松（Ba1～Ba4），10个21-酰胺基氢化泼尼松（Bb1～Bb10），4个21-酰胺基甲泼尼龙（Bc1～Bc4），4个21-酰胺基地塞米松（Bd1～Bd4），1个21-酰胺基倍它美松（Be1），1个21-酰胺基RS（Bf1），1个21-酰胺基可的松（Bg1），1个21-酰胺基强的松（Bh1）。21-酰胺基分别为乙酰胺基、烟酰胺基、单琥珀酰胺基、苯甲酰胺基、甲烷磺酰胺基或取代苯磺酰胺基等。

Stable Vitamin K 3 is synthesized by addition reaction of raw materials of niacinamide, chlorhydric acid and menadione sodium bisulfite at 25℃.

以烟酰胺、盐酸为原料，在 2 5℃反应得烟酰胺盐酸盐溶液，而后与亚硫酸氢钠甲萘醌发生加成反应，反应的物料配比为：n ∶ n ∶ n =1∶1.2 ∶1.2 5 ，得到稳定的复合维生素K3 ，收率 95 %。

Results Nicotinamide at 1-5 mg/ml induced apoptosis of GLC-82 cells in a dose-dependent manner, and group 4 mg/ml and group 5 mg/ml showed increased apoptosis than other groups. Distinct morphologic changes of cell apoptosis such as karyopyknosis and conglomeration were observed; Cell migration became slower as the dosage of Nicotinamide increased;Cells produced an arrested at G1 phase, accompanied by a reduction of cells transiting through S phase.

结果 烟酰胺诱导细胞凋亡程度与用药剂量呈正相关，较高剂量的药物能引起GLC-82肺腺癌细胞呈现边界不清，体积缩小，核固缩，染色质凝集、边缘化，甚至细胞发生破碎，凋亡小体形成；随着烟酰胺浓度的增高GLC-82细胞向划痕区的愈合速度不断减慢；烟酰胺的浓度大于等于3 mg/ml 时，细胞周期主要表现为G1 期比例的上升伴随S期比例的下降。

This thesis studies the analytical methods of determination of Leucogen and Hydroxymethylnicotinamide by Ultraviolet and Atomic Absorption Spectrscopy.

本文研究了分光光度法和原子吸收光谱法测定利血生及羟甲基烟酰胺的分析方法，提出了利血生的三种测定方法和羟甲基烟酰胺的一阶导数峰-零法的测定新方法，并用于实际样品的测定，获得满意结果。

As nicotinic acid and nicotinamide possess the resemble biology function, it also synthesizes the second type of two kinds new organic chromium of containing nicotinamide,〓 and 〓.

基于烟酸与烟酰胺相似的化学结构与生物学功能，合成了第二类两种含有烟酰胺配体的有机铬配合物，其组成分别为〓和〓。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。