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炎症

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Based on these results, it is suggested that theinhibition of NO and prostaglandin E2 over-production throughsuppressing iNOS and COX-2 induction and attenuation of TNF- formation and neutrophil infiltration into inflammatory sitesby C-PC may contribute, at least in part, to its antihyperalgesicactivity.

这些研究结果提示, C-PC 的镇痛活性至少部分是通过抑制炎症部位 iNOS 和 COX-2的诱导作用和减少 TNF-的形成及中性粒细胞的浸润来抑制 NO 和前列腺素 E2的过多生成而产生。

Preterm labor can be more accurately predicted by combination detection of plasma P-LAP and IL-6. The oversecretion of IL-6 may lead to the decrease of P-LAP, which may be the key factor for spontaneous preterm labor.

对有自发性早产先兆的孕妇进行P-LAP和IL-6联合检测,能更准确地预测早产;IL-6等促炎症细胞因子分泌增多,导致P-LAP水平下降,可能是自发性早产的关键因素。

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors.

最终在兴奋性毒性(过度刺激神经元上的递质受体)、钙紊乱、炎症、能量和生长因子缺乏作用下,敏感的神经元发生萎缩、死亡。apoE4与Aβ和tau的异常聚集有关,还可能损伤线粒体和其他细胞骨架。Aβ、tau、apoE和synuclein与其他分子相互作用,影响多种神经活动和存活的信号转导途径。

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors. A form of apolipoprotein E, apoE4, contributes to the abnormal accumulation of A and tau, but probably also damages mitochondria and the cellular cytoskeleton. A , tau, apoE and -synuclein interact with many other molecules and modulate diverse signalling cascades that regulate neuronal activity and survival.

最后,易感神经元会萎缩直至死亡,原因可能有兴奋性中毒(神经递质对神经元表面受体的过度刺激引起),钙稳态失衡,炎症反应,能量和生长因子的耗尽。apoE4的产生可导致A肽和tau蛋白的异常聚合,可能也损害线粒体和细胞骨架。A肽、tau蛋白、apoE和突触核蛋白可与很多分子反应,也可调节不同信号级联反应,这些级联反应对于维持神经元活动性和生存性意义重大。

Results: The oviduct tissues of the models manifested with chronic inflammation.

结果:模型大鼠输卵管组织呈慢性炎症表现。

Cardiovascular disease is one of major threats to human health and closely related to inflammation and oxidative stress in vascular system.

心血管疾病是威胁人类健康的主要疾病,它与炎症反应和氧化应激有着密切的联系。

Objective To determine the protective effect of cardiopulmonary bypass with autologous lung as oxygenator on CPB-relative inflammatory response.

目的:探讨以自体肺取代人工肺的体外循环方法对犬体外循环相关性炎症反应的影响,阐明其作用机制。

objective cardiopulmonary bypass is known to introduce inflammatory response and reperfusion injury in association with lung injury,to study this,32 cases of rat cpb model were made. methods isolated rat lungs were used as the oxygenator.

体外循环后肺部并发症依然是困扰心外科的一大难题,是小儿心脏手术后主要死亡原因之一。cpb中的肺损伤主要由体外循环中血液与非生理性管道界面接触引发的全身炎症反应以及肺的缺血再灌注损伤造成[1]。

METHODS Isolated rat lungs were used as the oxygenator. Venous blood from experimental rats was oxygenated in isolated lungs and then was perfused into the aorta of experimental rats by pump.

CPB中的肺损伤主要由体外循环中血液与非生理性管道界面接触引发的全身炎症反应以及肺的缺血再灌注损伤造成[1]。

Several lines of evidence have implicated ETs in the spatic response to SAH. First, hemolysate such as oxyhemoglobin can increase the production and release of ET.

国内外研究显示,具有强力缩血管作用的内皮素1(ET-1)和白介素6(IL-6)等炎症因子在血管痉挛的病理生理过程中具有重要作用。

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The objective is to subjugate and discourage the people, because that allows the elite to continue to rule unopposed.

其目的是压制和打击人民的积极性,因为这可以让实权派继续统治不会沦为反对派。

GOD,this is the second time you vanquished me!

天啊,这是第二次你打败了我!

So a kind of strong antagonism permeated in the relations of two countries.

所以两国这一时期的政治关系始终弥漫着一种强烈的对抗情绪。