炎性的

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活，ICAM-1表达升高，与被激活的PMN表面表达的LFA-1相结合，"PMN-EC"相互作用加剧，一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍；另一方面粘附的PMN过度吞噬或激活，当白细胞吞噬的颗粒不能被封闭隔离，连同细胞内的酶被释放出来，其中的PMN-elastase能够降解细胞基质中各种成分，水解多种蛋白，加重胰腺的毛细血管内皮细胞和腺泡的损伤；释放的溶酶体酶使组织蛋白水解，产生的不饱和脂肪酸引发脂质过氧化方应，破坏细胞膜的结构和功能；释放的炎性细胞因子，激发其他的免疫细胞的功能，导致进一步的组织损伤和坏死，加重SAP的病理损伤，最终导致休克、脓毒血症及多器官功能障碍等严重后果。

Between July 2003 and April 2005, the investigators randomly selected 2,650 individuals aged 50 to 75 years from the Social Security Register of the Canary Islands for participation in the study. They excluded all those with regular use of nonsteroidal anti-inflammatory drugs or anticoagulants, recent history of screening for colorectal cancer or digestive tract bleeding, and a family or personal history of colorectal cancer, inflammatory bowel disease, or coagulopathy. The remaining 2,020 participants, considered to represent a population at average risk for colorectal cancer, were asked to take the GOBT and IOBT and were also invited to undergo a colonoscopy. Of these patients, 1,559 (77%) completed both fecal occult blood tests.

在2003年7月及2005年8月之间，研究人员以随机的方式选定了2，650位50到75岁的患者参与试验，皆来自Canary Island社会安全登录的资料；使用非类固醇抗炎药物或抗凝结药物者皆会被排除，另外会被试验排除的因素，包含大肠直肠癌或消化道出血阳性者，有个人大肠直肠癌病史或家庭病史者、发炎性肠道疾病者及凝血病变者等；剩下的2，020位参与者，被视为足以代表大肠直肠癌的平均风险族群，这些患者被要求测试GOBT及IOBT，而且也进行直肠镜检查；这些患者中，有1559位(77%)完成了两项的粪便潜血试验。

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活，ICAM-1表达升高，与被激活的PMN表面表达的LFA-1相结合，&PMN-EC&相互作用加剧，一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍；另一方面粘附的PMN过度吞噬或激活，当白细胞吞噬的颗粒不能被封闭隔离，连同细胞内的酶被释放出来，其中的PMN-elastase能够降解细胞基质中各种成分，水解多种蛋白，加重胰腺的毛细血管内皮细胞和腺泡的损伤；释放的溶酶体酶使组织蛋白水解，产生的不饱和脂肪酸引发脂质过氧化方应，破坏细胞膜的结构和功能；释放的炎性细胞因子，激发其他的免疫细胞的功能，导致进一步的组织损伤和坏死，加重SAP的病理损伤，最终导致休克、脓毒血症及多器官功能障碍等严重后果。

Reduce the hoist of leucocytes of sinus coronaries blood of myocardial ischemia and reperfusion injury dogs;2. decrease the leakage of plasma CK, CK-MB and LDH;3. regulate the vaso-active substances such as ET, TXB〓 and PGI〓;4. decreased the inflammatory cell factors such as IL-1, IL-6 and TNF

综上，奥沙恩注射液可降低心肌缺血再灌注损伤模型犬冠状窦血白细胞总数，减少I／R后CK、CK-MB和LDH的释放，调节血管活性物质ET、〓和〓的产生，降低血清炎性细胞因子TNF-α、IL-1和IL-6的含量，抑制PMN的激活及对心肌的浸润，减轻心肌组织的病理改变，以及减轻心肌缺血及坏死程度、降低心肌耗氧量，从而显示出较强的对犬急性心肌缺血再灌注损伤的保护作用。

This preliminary case control study reconfirms that TWHf is a very potent herbal remedy to suppress mononuclear expressions of many inflammatory cytokines and pro-inflammatory molecules.

尽管只有少数的研究对象，本篇研究提供了在免疫致病机转上的可能证据来支持雷公藤对於僵直性脊椎炎患者周边血液单核球细胞内的许多发炎性细胞激素及其它和发炎反应有关的分子的基因表现具有强烈的抑制作用的说法。

Minocycline represses diabetes-induced inflammatory cytokine production, reduces the release of cytotoxins from actiated microglia, and significantly reduces measurable caspase-3 actiity within the retina.

二甲胺四环素抑制糖尿病诱导的炎性细胞因子的产生，降低来自于活化的小神经胶质细胞的细胞因子的释放，同时显著降低视网膜内可检测的caspase-3的活性。

By the time of its fall, most of the prisoners were writers who had written against the corruptions of the government.

到它被攻陷的时候，里面多数的犯人是写了反对政府贪污文章的作家。

The most obvious variation to ovum morphological character was that the color was changed from light green to sepiaceous in embryonic development, and all the ovums were almost hatched after 96h.

在胚胎发育过程中卵的形态特征最明显的变化是颜色从淡绿到深褐色，卵在发育96h后卵基本全部孵化。