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灰质软化

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Their ages ranged 6 to 13 years. Their EEGs were characterized by continuous spike-and-wave discharges during non-rapid eye movement sleep, accounting for 85%-100% of the period of NREM sleep. Clinically, these children had various types of epileptic seizures and exhibited different degrees of neuropsychiatric impairments, language dysfunction, and/or behavioral disturbances. Neuroimaging abnormalities were found in 6 cases, including atelencephalia or atrophy, gray matter heterotopia and leucomalacia. CONCLUSIONS: This study indicates the characteristics of CSWS syndrome in clinical manifestations, EEG and neuroimaging examinations.

结果:9例患儿的视频脑电图结果符合CSWS诊断标准,年龄6~13岁,脑电图表现为棘慢复合波在整个非快速眼动睡眠期几乎持续存在,其放电时间占整个NREM期的85%~100%;临床上患者表现不同类型的癫癎发作,在神经精神方面存在不同程度的损害,存在言语和/或行为障碍;其中6例患儿显示有神经影像学异常,包括脑发育不全或萎缩、灰质异位、脑白质软化等。

Results According the MRI characteristric of hypoxic-ischemic encephalopath sequela:(1)The most common findings were white matter injury in 47 cases:①Periventricular leukomalacia in 23 cases;②Selective cerebral neuronal necrosis of basilar node lentiform nucleus and optic colliculus in 9 cases;③Corpus callosum damaged in 15 cases;(2)The most damaged of grey matter in 18 cases;(3)Focal or multifocal ischemic crerbral intenerate in 9 cases;(4)Diffuse crerbral injury in 5 cases.

结果 根据儿童缺血缺氧性脑病后遗症的MRI影像特点,将其分为:(1)脑白质损伤为主:47例;①脑室周围脑白质脱髓鞘、软化:23例;②基底节豆状核、视丘神经元选择性损害:9例;③胼胝体受损变薄:15例;(2)脑灰质损害为主:18例;(3)局部或多处脑软化:9例;(4)广泛脑损害:5例。

Results According the MRI characteristric of hypoxic\|ischemic encephalopath sequela:(1)The most common findings were white matter injury in 47 cases:①Periventricular leukomalacia in 23 cases;②Selective cerebral neuronal necrosis of basilar node lentiform nucleus and optic colliculus in 9 case...

结果 根据儿童缺血缺氧性脑病后遗症的MRI影像特点,将其分为:(1)脑白质损伤为主:47 例;①脑室周围脑白质脱髓鞘、软化:23 例;②基底节豆状核、视丘神经元选择性损害:9 例;③胼胝体受损变薄:15 例;(2)脑灰质损害为主:18 例;(3)局部或多处脑软化:9 例;(4)广泛脑损害:5 例。

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