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Objective: To study the effect and mechanism of gross saponins from Tribulus Terrestris Lon myocardium ischemia/reinfusion in mice.

研究目的:探讨蒺藜总皂苷对大鼠心肌缺血再灌注损伤的保护作用及其机理。

Results tRPJS significantly decreased the contents of NOS and iNOS in hippocampus region of MCAO rat and cerebral ischemia reinfusion mouse.

结果 tRPJS能显著降低脑缺血再灌注损伤小鼠和局灶性脑缺血大鼠海马组织NOS、iNOS的含量(P.05)。

By adopting 4-vessel-occluded cerebral ischemia and reirrigate rat model.

采用四血管阻断的大鼠急性脑缺血再灌注动物模型。

Objective:To explore the improved technique of mouse cervical heterotopic heart transplantation and study cardiac transplantation rejective reaction and reperfusion injury.

目的探讨小鼠颈部心脏移植术的改进和研究心脏移植再灌注损伤及急性排异反应。

RESULTS:Naokangtai capsule improved the abilites of active and passive learning and memory remarkedly in the model mice with cerebral ischemia-reperfusion injury,but there was no influence to the contents of MDA,SOD and MAO.In senile dementia mice induced by D-galactose,Naokangtai capsule possessed obvious effects of improving memory and spatial resolution and decreased contents of MDA and MAO in blood significantly.

结果:脑康泰胶囊显著增强脑缺血再灌注损伤模型小鼠被动和主动学习能力,但对血液MDA、MAO和SOD含量影响不显著;脑康泰除明显增强老年痴呆小鼠主动学习和空间分辨的能力外,还能显著降低小鼠血液中MDA和MAO水平。

Directed PCI is safe and effect method for early reperfusion of coronary in AMI,it can increase repatency rate of IRA,improve heart function,and decreased complication.

直接PCI是AMI早期再灌注安全有效的方法,能够提高IRA 再通率,改善心功能,减少并发症。

Results 45 infarct related arteries among 40 cases acquired coronary artery repatency with TIMI 3 degree flow, a success rate of 95.2%(40/42), the residual stenosis in repatency coronary arteries was from 0 to 20%. The clinic symptom of the 5 cases with left ventricular dysfunction and 2 of the 3 cases with cardiogenic shock were obviously improved, 1 case(2.5%) with cardiogenic shock was dead in hospital.

结果 40例患者中的45支梗塞相关血管获得再通,成功率达95.2%(40/42),均达到TIMI-3级血流灌注,再通血管残余狭窄0%~20%。5例合并左心功能不全(Killip分级Ⅱ~Ⅲ级)及3例合并心源性休克患者术后症状明显改善,住院期间1例死亡(病死率2.5%)。

After 5 hours ,make them rewarm in the room .the rats of the ischemia/reperfusion group is kept natal temperatures 37C+ 0.5C heating by head-lamp .

缺血再灌注对照组用头灯加热的方法使大鼠肛温维持在37±0.5℃。

AIM: To investigate the effects of safflor injection on expression of cyclooxygenase-2 mRNA during lung ischemia/reperfusion injury in rabbits.

目的:探讨红花注射液对肺缺血/再灌注损伤时环氧酶基因表达的影响。

Objective To determine the inhibitory effect of safflor injection on the level of serum interleukin-8 (IL-8) following cerebral ischemia and reperfusion injury in rabbits.

目的观察红花注射液对脑缺血/再灌注损伤家兔血清白细胞介素-8(IL-8)水平的影响,并探讨其脑保护机制。

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