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METHODS: In 10 open-chest anesthetized pigs, myocardial deformation was studied before and during dobutamine infusion, under control and ischemic conditions produced by various degrees of coronary artery constriction: 2 of nonflow-limiting stenoses of increasing severity reducing left anterior descending artery hyperemic flow by 40% and 70% and 2 flow-limiting stenoses reducing resting coronary flow by 25% and 50%.

10只麻醉开胸的猪以各种程度的冠脉压缩制作为缺血状态组或对照组,研究其多巴酚丁胺灌注前后心肌损伤情况。2只无血流限制狭窄猪模型予以渐增的左前降支血流充盈减少分别为40%和70%,2只血流受限狭窄猪模型减少剩余冠脉血流25%和50%。

Results The exoression of MMP-9 was significantly increased in hyperglycemic groups after irrigating 24h,48h post 2h ischemia.

高血糖可诱导脑缺血再灌注后脑组织内的MMP-9 表达,增加血脑屏障的通透性,从而加重脑组织的损伤。

Results:The pathological diagnosis was gained by laparoscopy,and got a satisfactory curative effect by intraperitoneal hyperthermal perfusion chemotherapy,while all patients were difficult to make a definite diagnosis in routine examination.

结果:患者在常规检查难以确诊的情况下,应用腹腔镜技术均获得病理确诊,经用腹腔热灌注化疗,取得满意疗效。

Objective To investigate the clinical effect of intraoperative and postoperative peritoneal hyperthermic chemotherapy in advanced gastric cancer in eldly patients.

目的:探讨老年胃癌根治术中及术后腹腔内温热灌注化疗的临床疗效及对肝功及血液系统的影响。

Intraperitoneal hyperthermic perfusion chemotherapy combined with venoclysis can prevent recurrence and metastasis effectively,and improve the survival rate and quality of life of postoperative gastric cancer patients.

胃癌术后腹腔热灌注联合静脉化疗可有效控制复发和转移,提高胃癌术后病人的生存率和生存质量。

[Purpose] To investigate the significanceof early continuous hyperthermic peritoneal perfusion chemotherapyin treatment for advanced gastric cancer patients after operation.

[目的]探讨进展期胃癌术后早期腹腔持续温热灌注化疗的意义。

Retrograde hyperthermic cardioplegia(42℃) can effectively induce the expression of HSP70mRNA in the isolated rat heart,associated with the increase in mechanical function and improvement in energy metabolism.

42℃含氧停搏液灌注离体鼠心能快速诱导HSP70mRNA的表达,对长时间冷停搏的心脏在机械功能和能量代谢等方面均有保护作用。

Objective To evaluate the effects and toxicities of hyperthermic peritoneal perfusion with oxaliplatin plus 5-FU/LV for senile patients with malignant ascites.

目的研究草酸铂腹腔热灌注联合5-氟脲嘧啶/亚叶酸钙(5-FU/LV)方案治疗老年癌性腹水的疗效及不良反应。

Methods An isovolumic Langendorff perfused rat heart model was used.After 30 minutes of equilibrating perfusion,the HSPT group(n=8) was preconditioned by 15 minutes of hyperthermic oxygenated cardioplegia at 42℃(Control,n=8,at 37℃),before 100 minutes of cold preservation,followed by 30 minutes of reperfusion.

Wistar大鼠16只,随机分为HSPT组(n=8)和对照组(n=8),建立Langendorff离体鼠心等容收缩模型;平衡灌流30分钟后,分别用42 ℃和37 ℃的含氧停搏液灌注15分钟,然后冷停搏100分钟,再灌30分钟。

Compared with 37 patients of simple venous chemotherapy,34 patients of large intesinal cancer after radical resection were treated by intraperitoneal hyperthermic chemotherapy with carboplatin,DDP and 5-Fu.

方法对 3 4例大肠癌根治术后行DDP、5 -Fu腹腔内灌注,与 3 7例根治术后静脉化疗相比较。

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