灌注

Objective To investigate the effects of Carthamus tinctorius on infarction volumes,apoptosis of neurons and bcl-2,caspase-3 expressions after acute injury of cerebral ischemia and reperfusion.

目的 探讨红花注射液对大鼠急性脑缺血再灌注损伤后梗死体积和神经元凋亡及凋亡相关蛋白bcl-2，caspase-3表达的影响。

Carthamus tinctorius injection has significant effect on the up-regulation of bcl-2 and down-regulation of caspase-3 expression in renal ischemia/reperfusion injury.

在肾缺血再灌注损伤过程中，红花注射液具有抑制Caspase-3表达和促进bcl-2表达的作用。

METHODS: On the basis of twocuff technique of Kamada, weve improved the techniques of separating, perfusing donor liver, the shearing and anastomosis of the superior and inferior caval veins, the bile duct anastomosis, and so on.

在Kamada两套袖法基础上，着重对供肝分离、灌注、肝上下腔静脉切取，肝上下腔静脉吻合，胆管吻合等手术方法作了进一步改进。

Objective To study the protective effect and mechanism of endothelin-1(ET-1)-re- ceptor antagonist PD142893 on early ischemia-reperfusion injury in rats lung allografts.

肺缺血再灌注损伤是肺移植术后早期死亡的主要原因，寻找有效方法预防和减轻肺IRI，有着重要的临床意义〔'一3〕。

The Langendorff model was used, and isolated perfusedrat hearts were separated into untreated, isoflurane, chelerythrine plus isoflurane, and chelerythrine groups.

使用 Langendorff 模型，离体灌注大鼠心脏被分为未治疗组，异氟醚组，白屈菜红碱加异氟醚组和白屈菜红碱组。

However it was shown its eventually inhibiting effect on apoptotic myocyte cells during I〓 R〓h (P＜0.05); The PKC inhibitors chelerythrine and scutellarein have no effect on expression of Fas protein, whereas they can significantly upregulate the expression of Bcl-2 protein.

4PKC激活剂PMA可下调Fas基因的蛋白表达，对Bcl-2蛋白的表达也有抑制作用，它对缺血30min、再灌注24h后心肌凋亡细胞的最终影响为抑制效应(P＜0.05)，而PKC抑制剂CHE、灯盏花素对Fas基因蛋白表达无明显干预影响，但对Bcl-2蛋白表达呈显著上调作用，故对心肌细胞凋亡的抑制作用更为明显(P＜0.01)。

In 15 anesthetized open-chest dogs, the responses of some regional vascular beds were examined by constant flow perfusion method during the 5-HT-induced aortic hypertensive chemoreflex.

在15只麻醉开胸犬中，用在体器官恒流灌注法研究了骨胳肌、皮肤、肾和心脏的血管在5-HT诱发的主动脉区化学感受性升血压反射中的反应，同时还观察了5-HT对这些器官血管的直接效应。

Objective To investigate the expression of chemokines chemotactic for CD4+T cells in rat myocardium during ischemia reperfusion injury.

目的 检测大鼠心肌缺血再灌注中诱导CD4+T细胞趋化的趋化因子的表达。

Result The expression of chemotactic chemokines for CD4+T cells increased rapidly as early as at 2 h after reperfusion, and then declined subsequently.

结果 诱导CD4+T细胞募集的趋化因子的表达在再灌注2 h即迅速增高，随后出现下降。

The results suggeste that MIP2, one of the neutrophil chemotactic factors, plays an important role in the liver injury induced by I/R in rats.

结论MIP2在大鼠肝缺血/再灌注损伤中作为中性粒细胞的趋化因子之一起着重要的上调作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。