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Furthermore, we analyzed the possible mechanism. Methods: We established the arterially perfused rabbit left ventricular wedge preparations to record transmembrane ECG and action potentials of the epicardial cells and endocardial cells simultaneously. We divided two groups by setting the location of premature beats.

本试验以冠状动脉灌注兔左心室楔形组织块标本为研究对象,观察期前刺激位置对单向传导阻滞的时间易损窗的影响、单向传导阻滞和折返激动时间易损窗的关系及折返起源部位等,并分析其可能机制。

In HMI group and AAP10 group, the circumflex coronaries were ligated. In sham group, left thoracotomy was performed without coronary ligation. The animals were feed three months before the study and an arterially perfused rabbit left ventricular wedge preparation was made.

Sham组开胸但不结扎冠状动脉,HMI组和AAP10组开胸并结扎冠状动脉左室支制备心梗模型,普通饲料喂养三个月后制备兔左心室楔形心肌块的灌注模型。

To investigate the role of transmural dispersion of repolarization and cardiac restitution properties in arrhythimogeneity in LQT2, we observed the effects of d, 1-sotalol, hypokalemia and calcium channel blocker on TDR and cardiac restitution properties at different basic cycle length by using the arterially perfused rabbit left ventricular wedge preparation.

为探讨心室跨壁复极离散度和动作电位时程恢复性质的变化在LQT2室性心律失常发生中的作用,笔者采用冠状动脉灌注的兔左室肌楔形组织块制备LQT2模型。标本随机分四组:对照组;LQT2模型组(100 mol/L d,1-sotalol灌流);模型+低钾(3 mmol/L)组和模型+低钾+维拉帕米(2 mol/L)组。

When the organ perfusion pressure changes, the arteriole resistance also change to keep the organ blood flow at a constant level, which is called the autoregulation of the blood flow.

当器官灌注压发生变化时,该器官的微动脉阻力也发生改变,使器官的血流量保持相对恒定的现象称为血流量的自身调节。

① The main peak form can be used to evaluate vascular tone and elasticity of the small arteries and arteriole, and to monitor the microcirculation blood flow.

①分析指端光电容积脉搏波峰形动态变化有助于评估人体小动脉和微动脉血管紧张性和弹性,监测微循环血流灌注变化。

Objective To study the effects of β-asarone on mitochondrial membrane potential of cardiac myocytes with ischemia reperfusion injury.

目的 观察石菖蒲有效成分β-细辛醚对缺血再灌注损伤心肌细胞线粒体膜电位的影响。

The lately reports have show that incidence of spinal cord ischemia eperfusion injury is 3%~18% assumably.

最近报道显示脊髓缺血再灌注损伤发生率约为3%~18%。

As an atraumatic, sensitive and accurate imaging method, it combined digital process of both contrast enhancement and contrast intensity changes. This new method will enjoy wide clinical application with its quantitative indexes of perfusion.

作为一种无创、敏感、准确的功能成像手段,超声造影定量技术结合了造影剂造影的动态过程和造影强度变化过程,能以量化的方式客观而准确地反映组织中血流灌注的改变,具有独特的优势和广阔的应用前景。

Methods Renal ischemia/reperfusion injury model was made by placing an atraumatic vascular clamp on renal pedicle. The morphologic change was observed with transmission electron microscope.

目的 观察老年大鼠缺血/再灌注肾损伤修复时细胞外信号调节激酶、c-Jun氨基末端激酶的变化,探讨其与老年大鼠肾脏早期损伤修复的关系。

Methods] Healthy SD rats were divided randomly into 6 group, including: normal control group(sham-operation), ischemia for 45 min (reperfusion 0h, n=6), reperfusion 2,4,12 and 24 hr group. Renal ischemia reperfusion injury models were founded in other five groups, opened abdominal and placed atraumatic vascular champ in dual kidney pedicle for 45 minutes,followed by reperfusion 2,4,12 and 24 hr.

方法] 将SD大鼠随机分成正常对照组、单纯缺血组、再灌注2 h组、4 h组、12 h组、24 h组,制备双侧肾蒂夹闭模型后,腹主动脉取血测血肌酐、尿素氮,行肾脏组织病理学检查,免疫组化法检测TGFβ1 蛋白,RT-PCR法检测TGFβ1 mRNA。

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