激活的

IL-1 and/or IL-2 have no effect on CFU-GM of ABM.

IL-1和IL-2对激活骨髓的CFU-GM水平无明显影响。

If you don't your account will show a negative balance.

如果你不这样做，你的帐号将显示为没激活

Aim To investigate the effects of gene expression through activating endothelial target for acetylcholine.

目的研究激活乙酰胆碱作用靶标血管内皮细胞基因表达的影响。

There is a small action range in archery.Simple methods and analysis is inadequate,so the author,on the basis of testing the archery athletes in national team with the Qualisisy infrared photoelectric testing system,Footscan sole pressure testing system,Noraxon myoelectricity remote testing system, etc,analyzes comprehensively the action technique of the athletes in national team from the posture,body motion characteristics,body posture equilibrium and stability,distribution of centre sole pressure, myoelectricity characteristics,etc,with the methods of relative software and data statistics.The conclusions and the suggestions are as follows:Conclusion:Firstly,the communality of posture angle,muscle strength,the activation order of main muscle during raising the bow, raising the bow and the timing of the raising could be used as the evaluation index of technique action in archery;Secondly,the length of the time needed in the different periods couldn\'t be used as technique evaluation index since it has no relation with the result.But the time of raising and pulling back the row is relatively fixed,and the time has a positive relation with the archery achievement of the national team in China.Thirdly,the central index of the sole pressure could be used as the reference criterion of selecting athletes and forecasting achievement.During playing archery,the interrelation between the central index of the sole pressure and the achievement is different individually and in different periods.Fourthly,there is low stability of the archery athletes in the front and back direction during the action, caused by the athletes\' posture disequilibrium of dorsal abdominal muscle and non-professional sport shoes..Fifthly,kinematics and electromyography shows that the people on archery in China haven\'t taken the raising and pulling back the row seriously.

射箭的肢体动作幅度小，简单的手段和分析不能满足其需要，笔者结合各种运动生物力学仪器优点及射箭项目的特性，选用Qualisisy红外光点测试系统、Footscan足底压力测试系统、Noraxon肌电遥测系统等对国家队射箭队运动员进行多方位的测试，运用相关软件及数理统计方法，对运动员的射箭动作技术，从射箭动作的姿态构架、肢体运动特点，身体姿态平衡稳定性、足底压力中心分布、肌电特性等进行全面分析，结论及建议如下：结论：第一，姿态角、肌肉用力激活程度、举弓阶段主要用力肌肉激活顺序、举弓、开弓时间等的一致性可作为射箭技术动作评价指标；第二，各动作阶段所用时间的长短不能作为技术评价指标，但举、开弓的时间相对较固定，开举弓时间比与中国国家队射箭成绩正弱相关达到显著性；第三，闭眼状态下足底压力中心单位面积轨迹长与144支箭最好成绩正相关达到显著性，可作为身体素质、选材及成绩预测的参考依据；实射时身体平衡的足底压力中心指标与成绩的相关程度具有个体性差异、阶段性差异；第四，射箭运动员实射时身体在前后方向上的稳定性较差，这与运动员的站立姿态、腹背肌力量的不匹配以及射箭没有专业运动鞋有关；第五，运动学及肌电学都表明中国射箭训练对举弓、开弓阶段的重视不够，背部肌肉用力特征不明显，撒放技术合理性不高。

NodD binds to and bends target promoters through anchoring two tandem and individual specific DNA sites. NodD functions as a tetramer, which has a V-shaped main body. Tetrameric NodD is to change its own conformation rather than its oligomeric forms in response to small signal molecules. The specific interaction between each NodD DNA-binding domain and each specific DNA site does not alter itself in spite of naringenin induction, and the induced conformational change is transferred from protein to DNA. Only the DNA conformation incited by induced NodD is competent for RNA polymerase to form the transcriptional open complex. It cannot be excluded that NodD may have protein-to-protein contacts with RNA polymerase, and that the NodD conformational change may also directly contribute to the transcriptional open complex formation. However, the NodD conformational change itself cannot serve as the determinant of the transcriptional molecular switch.

通过研究，我们提出了初步的NodD操纵子激活模型：第一，四聚体是NodD蛋白的功能单位，它通过铆钉两个串联的相对独立的DNA靶位点结合被诱导的启动子；第二，小分子配基的结合是改变NodD四聚体的构象而不是引发不同形式的寡聚体，在我们的模型中，NodD四聚体缩小其V形主体的弯折角，进而缩短其DNA结合功能域的间距；第三，小分子信号的诱导并没有改变NodD的DNA结合域和其DNA靶位点的相互作用，NodD的构象改变由蛋白质经其双铆钉位点传递给DNA；第四，只有诱导状态的NodD激发的DNA构象才能有效地使RNA聚合酶形成转录开放复合物；第五，不排除NodD与RNA聚合酶可能有直接的相互接触位点，不排除NodD构象的改变可能直接有利于RNA聚合酶形成转录开放复合物，但是我们认为NodD构象改变本身不是充当转录激活开关的决定因素。

Recently, it is found that the neuron apoptosis caused by brain ischemia is associated with signal pathway of endoplasmic reticulum stress, which is different from the traditional apoptotic pathway. Caspase-12 has been identified as a molecule which initiates apoptosis selectively in response to ER stress and is not activated by other pathways. Caspase-12 is localized on the ER membrane, but once specifically activated by ER stress, it translocates to the cytoplasm.

最近的研究发现，这种细胞凋亡与内质网应激(endoplasmic reticulum stress ER stress)有关，其是一种不同于经典的凋亡途径的新途径，分子伴侣葡萄糖调节蛋白78(glucose regulated protein， GRP78/Bip)表达增高是反应ER stress的最敏感的指标，胱冬酶-12(caspase-12)为鼠源性的内质网膜上的蛋白，它的特点是只被内质网诱导的凋亡所激活而不被其它非内质网因素所激活。

Activation of the surface DORs causes a slow Ca〓 elevation by both inositol 1, 4, 5-trisphosphate receptor-mediated intracellular Ca〓 release and extracellular Ca〓 entry, resulting in a slow and long-lasting increase in intracellular Ca〓, exocytosis, DOR insertion and CGRP release.

激活DOR引起的DOR的上膜是依赖于LDCV与细胞膜的融合和细胞内的钙离子升高。激活DORs可以引起胞内IP3钙库的释放，和一种不通过电压依赖性钙通道的外钙内流；从而引起DOR的上膜和神经肽的分泌。

The effect of AA on BEL-7402 was not significant; However, AA could effectively enhance AT-induced hepatocarcinoma cell apoptosis and lesion severity through activation of caspase-3 but not ERKs-Conclusion; Caspase-3 and ERKs proteins could involve in arsenic-induced hepatocarcinoma cell apoptosis and differentiation respectively as intracellular signaling molecules; The effect between AT and AA on hepatocarcinoma is synergistic, which further inhibits cell growth and induces apoptosis in human hepatocarcinoma cells through activation of caspase-3 but not ERRs.

AA对BEL-7402无明显的作用，但能有效的通过caspase-3而不是ERKs的激活促进AT对肝癌细胞的凋亡效应。结论：ERKs和caspse-3信号蛋白可能分别参与了砷剂诱导的人肝癌细胞促分化和凋亡效应，AT和AA对肝癌细胞的作用有协同性，他们通过caaspase-3而不是ERKs的激活进一步抑制了肝癌的生长，诱导其凋亡。

In the ultra high vacuum activation, reduction of the vanadium oxide started at a lower temperature (250℃ to 300℃), and the reduction of the titanium oxides started at a higher temperature(300℃).

当吸气剂置于高真空激活时，钒的氧化物在较低的温度(250℃~300℃)开始被还原，钦的氧化物在稍高于钒的温度(300℃)也开始被还原，400℃时表面已经有大量的金属钦的存在，而Zr的氧化物在(100℃~400℃)激活过程中，则没有明显的变化。

This study is aimed to address the question whether the early discharges can affect thesilent period and modulate the late discharges and to investigate the possiblerole of dysfunction of primary myelinated afferents in generation of chronicpain. In addition, we also investigate the effect of the precedingA-conditioning stimuli with graded numbers on the late discharges of WDRneurons evoked by a following nociceptive test stimulus that activates bothA- and C-fibers.

在定义WDR神经元的反应特性时，通常用一个短促的电刺激刺激相关的神经干，激活A及C类纤维，这时可记录到一个反映有髓纤维传入的高频短促的早成分放电，接着是一个无放电的宁静期，最后是C纤维激活所诱发的晚成分放电，这种放电形式有别于脊髓背角的其它神经元。

The objective is to subjugate and discourage the people, because that allows the elite to continue to rule unopposed.

其目的是压制和打击人民的积极性，因为这可以让实权派继续统治不会沦为反对派。

GOD,this is the second time you vanquished me!

天啊，这是第二次你打败了我！