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Metal ions of Mn2+ stimulate the ChoA activity and Ca2+ significantly stimulate the ChoB activity, while Cu2+, Fe3+, and Ag+ inhibited them.

酶A的活性能够被Mn~(2+)激活,酶B的活性则能够被Ca~(2+)激活,Cu~(2+),Fe~(3+)和Ag~+则对两种酶的活性都有抑制作用。

BBR can activate extracellular-signal regulated kinase signaling pathway in liver cells very rapidly and dose dependently in vitro.

BBR在体外能迅速激活细胞的胞外信号调节激酶信号转导途径,ERK的激活作用在时间上提前于LDLR的表达增加。

While bilateral area lying along the intraparietal sulcus showed decreased activity during arithmetic with disruption, which might be related to the impaired arithmetic processing in dual task.

反之,双侧沿顶内沟区在心算受到干扰后的激活却显著弱于无扰时的激活,这或许是由加干扰后无法很好地完成心算造成的。

Mizumura K,Kumazawa T. Modification of nociceptor responses by inflammatory mediators and second messengers implicated in their actiona study in canine testicular polymodal receptors.

痛过敏的产生有赖于许多炎症介质的参与,如PGs,缓激肽,5-羟色胺和白介素B4等,这些炎症介质有的可敏化伤害性感受器,使它们的阈值降低,有的可激活伤害性感受器,有的具有敏化和激活双重作用[4~6]。

The Western blot results were consistent with those of immunohistochemical method. CONCLUSION: p38 MAPK expression increases in alveolar and airway epithelial cells in LPS induced acute lung injury rat models. The activation of p38 MAPK is found in most lung tissues, suggesting that p38 MAPK participates in the signal transduction in inflammatory and noninflammatory cells.

LPS诱发的大鼠急性肺损伤模型中,磷酸化p38 MAPK在气道和肺组织内表达增加,p38 MAPK的激活见于肺组织内多数细胞,提示肺内炎性和非炎性细胞均有p38 MAPK信号分子的激活。

Right postcentral gyrus of frontal lobe(BA2,BA1),left inferior frontal gyrus (BA47),postcentral gyrus(BA43),right inferior parietal lobule(BA40),left superior temporal gyrus(BA22) and right insular(BA13) were evoked by twisting Shenmen point; But there were not evoked by acupuncture at nonpoint.

4神门穴主要激活了右侧额叶的中央后回BA2、BA1,左侧额下回BA47和中央后回BA43,其次为右侧顶叶的顶下小叶BA40,左侧颞叶的颞上回BA22,右侧脑岛BA40;而假穴没有激活脑功能区。

Right postcentral gyrus of frontal lobe(BA2,BA1),left inferior frontal gyrus (BA47),postcentral gyrus(BA43),right inferior parietal lobule(BA40),left superior temporal gyrus(BA22) and right insular(BA13) were evoked by twisting Shenmen point; But there were not evoked by nontwisting Shenmen.

5刺激神门穴主要激活了右侧额叶的中央后回BA2、BA1,左侧额下回BA47和中央后回BA43,其次为右侧顶叶的顶下小叶BA40,左侧颞叶的颞上回BA22,右侧脑岛BA40;而非捻转刺激神门穴没有激活脑功能区。

Cases are not required to use input data or to supply output data, but if any one case outputs a value to a tunnel, all must output a value (unless Use Default If Unwired, which we will discuss in a moment, is enabled from the pop-up menu of the output tunnel).

分支亦不是必须要求使用输入数据或供给输出数据的,但是如果任何一个分支输出一个数值给一个隧道,那就要求所有的分支都要输出数值(除非激活了Use Default If Unwired,这将在后面讨论,从输出隧道的弹出菜单激活该功能)。

The results suggest that the enhancement of GABA-activated currents by OT may suppress primary sensory transmission by potentiating pre-synaptic inhibition of GABA.

以上结果提示:OT受体激活后可能通过相应的胞内转导机制增强GABA激活电流,从而在初级感觉神经元水平加强GABA的突触前抑制作用而减弱感觉信息的传递。

The immunoglobulin like anti AChR antibody without complement binding activity is successfully made from a pathogenic anti AChR antibody IgG 637 by site directed mutagenesis.Key words:receptor, cholinergic;myasthenia gravis;point mutation;complement-binding;antibodies

本研究利用定点突变技术,从完型抗乙酰胆碱受体抗体IgG 637制备了不能激活补体的突变型抗乙酰胆碱受体抗体IgG 637/K 322 A,为最终制备出可用于治疗重症肌无力的无补体激活功能的单价抗乙酰胆碱受体抗体提供依据。

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The objective is to subjugate and discourage the people, because that allows the elite to continue to rule unopposed.

其目的是压制和打击人民的积极性,因为这可以让实权派继续统治不会沦为反对派。

GOD,this is the second time you vanquished me!

天啊,这是第二次你打败了我!

So a kind of strong antagonism permeated in the relations of two countries.

所以两国这一时期的政治关系始终弥漫着一种强烈的对抗情绪。