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The indicator element (2) is designed as a waveguide panel, wherein light beams propagate with total reflection and get outcoupled therefrom with a diffractive outcoupling system (2u), such as a grating structure or the like, which is configured as an indicator pattern, for producing an indicator pattern (2a) activable in the indicator element (2) by the action of light, such that divergent recesses and/or grooves of various sizes and/or shapes constitute divergent local gratings of various sizes and/or shapes, such as multi-shaped and/or binary pixels and/or units, the filling factor, shape, profile and/or size thereof being optimized in such a way that the diffraction efficiency is a function of place.

把指示元件(2)设计成波导板,其中光束以全反射方式传播并且从那里通过构造成指示图案的衍射外耦合系统(2u)、如光栅结构等得到外耦合,用于在指示元件(2)中产生可由光作用激活的指示图案(2a),使得各种尺寸和/或形状的分散的凹口和/或槽纹构成各种尺寸和/或形状的发散的局部光栅、诸如多形状的和/或二元像素和/或单像素的,所述局部光栅的填充系数、形状、轮廓和/或尺寸可以以这样的方式优化,使得衍射效率是位置的函数。

Results In all 12 normal children, the blood oxygen level-dependent signal was negative, and the maximum response appeared to be located in the anterior and superior part of the calcarine fissure, which may correspond to the anterior region of the primary visual cortex. However, in 24 cases of PVL, no activated pixels in PVC in 4; weak and tiny activation in 6; deviated activation in 8; and both tiny and deviated activation in 3 cases.

结果:正常对照组的激活区位于原始视觉区,BOLD信号变化均为负值,在24名PVL患儿中,枕叶平均激活像素数目减少,4例在PVC区没有激活,6例激活区体积明显减小,7例激活区易位,另有3例激活区明显减小并易位。

We didn\'t find activated points in cerebellum and deeper brain.3.Acupuncture of sham point can significantly activated BA2,6,8,13,21,37,40,44,45,47,putamen and other areas.Both the left and right side of the brain have activated points,but points on the right side are more than those on the left.Both sides of middle temporal gyms,parietal lobule,supramarginal gyms and the lentiform nucleus have obvious activated points.The activated points mainly concentrated in the cerebral cortex,the deep-activated are mainly in the putamen.4. Sham needling in sham point can significantly activate BA6, 8,9,10,18,21,37,40,43,44.The activated points are mainly distributed in the right side of the brain.The left side also has some activated points;5.In the comparasion of Acupunture and sham-needling in S J5,we find that BA8 and cerebellum have distinct regional activated points;6.In the comparasion of acupuncture in SJ5 and sham point,we find BA2 and left cerebellar regions have activated points;7.Sham needling in S J5 compared with sham point,we find BA7,8,9,18 and other areas have activated points,the main activated points are at the left brain.It is not difficult to find that the distribution of activated points are mainly in the middle brain,no obvious activated points at the temporal lobe.

结果:通过对数据的处理和分析,我们初步发现:1、外关穴真针刺能显著激活Brodmann area45、37、44、40、22、13、37、47区、海马、杏仁核、黑质等区域,小脑左侧更明显,左侧颞叶皮层激活点多于右侧,且脑部左侧深层激活点多于右侧;2、外关穴假针刺能显著激活BA46、44、41、13、40、37、19区等区域,激活点主要集中表现在大脑皮层,以颞叶为主,小脑及深部未发现明显激活点;3、非穴真针刺组结果分析初步表明,BA2、6、8、13、21、37、40、44、45、47区以及壳核等区域有激活点,大脑左、右侧均有激活点,但右侧更多,双侧颞中回、顶叶下小叶、缘上回及豆状核有明显激活点,激活点主要集中在大脑皮层,深部激活点主要在壳核;4、非穴假针刺能显著激活BA6、8、9、10、18、21、37、40、43、44区等区域有激活点,主要分布在大脑的右侧,左侧也有不少激活点,就其具体分布主要在颞叶和额叶,少部分分布在顶叶和枕叶;5、外关穴真针刺与假针刺对比发现,BA8区和小脑等区域有明显的激活点;6、外关穴真针刺与非穴真针刺对比发现BA2区、左侧小脑等区域有激活点;7、外关穴假针刺与非穴假针刺对比发现,BA7、8、9、18等区有激活点,主要反应点在左侧大脑的枕叶中回、楔叶,顶叶楔前叶及额上回、中回,就其分布不难看出主要在大脑中部,颞叶未见明显激活点。

Parthenogenetic activation is artificially induced by various kinds of physical and/or chemical methods.

人工孤雌激活方法包括物理性激活和化学性激活以及联合激活方法,人卵母细胞的孤雌激活多以化学激活为主。

There are default colors for unvisited links (hyper links that you have not accessed before), active links (those that are in the process of loading or being used), and visited links (those hyper links that you have already clicked on at least once).

页面的链接有三种颜色组成,没有浏览链接过的使用默认的颜色,激活的链接(那些正在读取或使用的超链接)和访问过的链接(那些点击过至少一次的超链接)。

In vivo, CXCR4-A549 and A549 cells were injected subcutaneously into nude mice(each group in 6).Four weeks later the mice were scarified and the tumors in situ and the lungs were taken out to be examined histologically.(3) Th cell cycle distribution was measured by flow cytometry to analyse the effect of SDF-1/CXCR4 in the cell proliferation and atoposis. The changes of the intracellular calcium concentration after SDF-1 activation were aslo measured by flow cytometry. Western blot was used to anlayse the phosphorylation of AKT and ERK, and the expression of MMP-2 and VEGF-C.

3为探讨SDF-1/CXCR4在肺癌侵袭和转移中的作用机制:①利用流式细胞仪检测CXCR4-A549与A549两组细胞的增殖和凋亡,分析上调CXCR4的表达后,对细胞生长周期的影响;②利用流式细胞仪检测两组细胞钙离子内流强度,分析SDF-1/CXCR4对钙离子通道活性的调控;③采用Western blot实验检测两组细胞PI3K/AKT、MAPK/ERK相关信号通路的活性,分析SDF-1/CXCR4可能激活的下游信号分子;④采用Western blot和RT-PCR检测两组细胞肿瘤转移相关基因VEGF-C、MMP-2的表达,探讨SDF-1/CXCR4与VEGF-C、MMP-2的相互作用关系。

This anion pump is composed of two subunits, the catalytic 63KDa ArsA, a hydrophilic protein, when purified, exhibits oxyanion-stimulated ATPase activity, the hydrophobic 45. 5KDa ArsB protein, located in the inner membrane of E. coli, is the putative anion translocating channel and also serves as the anchor for ArsA to attach on the membrane.

ArsATP酶由水溶性的63KDa的ArsA蛋白和膜整合的46KDa的ArsB蛋白组成,ArsA蛋白是催化亚基,具有亚砷酸盐和亚锑酸盐激活的ATP酶活性,ArsB蛋白则构成转运亚砷酸盐和亚锑酸盐的阴离子通道,同时作为ArsA蛋白在膜上的结合位点。

The results provide neuroimaging evidence for the existence of acupoint specificity. 2. the study on acupuncture of combined-acupoints. It was found that the cerebral areas activated by the acupuncture of combind-acupoints were not a simple combination of those activated by the acupuncture at single acpoint, even in some activation areas, the activation intensity is weaker than at a single acupoint, which implied the existance of inteaction between acupoints in the combined-acupoints acupuncture. 3.the effect of acupuncture durion. This study found that the cerebral responses to half minute and one minute acupuncture were the same as a whole. But the cerebral responses to the acupuncture of 3 minutes were clearly different from those of 1 minute.

针对针灸中的基本问题,我们主要开展了以下研究:1,穴位特异性问题,初步证明了穴位特异性的存在。2,组合穴位针刺的机制研究,发现组合穴位针刺所激活的脑区并不是单穴位针刺结果的简单叠加,说明组合穴位针刺时单穴位之间存在相互作用。3,针刺时间对针刺效果的影响,在针刺治疗时针刺时间的长短到底对针刺效果有什么影响还不清楚,我们的结果显示针刺半分钟和1分钟之间没有显著差异,但它们与针刺3分钟之间存在显著差异,说明针刺存在时间效应。4,针刺四关穴对老年痴呆病人治疗作用的研究。

The present study is involved in the expression of vitronectin , a ligand of integrin, on human spermatozoa and its role in fertilization; the expression of integrin α〓、α〓、β〓 sbunits on human and mouse oocytes and their relationship with maturation of oocytes; the reorganization of cytoskeletal protein, actin, of mouse oocytes mediated with RGD peptide binding with integrins; the roles and mechanisms of integrins in activation of mouse oocytes as trasmembrane signaling receptors, using the methos of cell culture, immunohistochemistry, flow cytometer, laser confocal microscope.

本课题采用细胞培养、免疫组化、流式细胞术、激光共聚焦显微技术进行以下四个方面的研究:整合素配体玻连蛋白在人精子的表达及其与精子功能状态及受精的关系:整合素〓在人、小鼠卵的表达及其与卵的成熟程度的关系:整合素介导小鼠卵内actin骨架蛋白的重组;整合素介导卵激活的早、晚期事件,包括卵细胞内钙离子浓度的变化及孤雌发育胚的形成,并探讨其机制。

Effects of various forceful methods on specific throwing ability improvement of throwers were analyzed for coaches and athletes reference in their training.

可以确认:投掷专项力量的发展对投掷能力的提高起决定性作用;肌肉训练以外的内源性强力手段,是投掷运动员在赛前利用神经—肌肉激活的原理使力量增强的,理论和实践都证明,它是快速挖掘肌肉潜能的行之有效的强力手段。

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