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Meanwhile, we investigated the mechanisms by which HDAC inhibitor NaBu stimulates ALAS2 gene expression.

我们发现NaBu不仅能上调红系细胞ALAS2基因的转录,而且能激活非红系细胞ALAS2基因的转录。

Pretreatment with icv injection of naltrexone, the immunosuppressive effects of acute hypoxia were partially blocked.

其对低氧体液免疫功能的抑制作用可能与激活交感神经系统有关。

A549 cell line was stimulated with LPS (10 μg/mL) and then treated with Rs504393 (10 μg/mL) for 6 hours. ALI model was established with intranasal administration of LPS (5 mg/kg) in C57BL/6J mice. RS504393 (5 mg/kg) was administered 30 min before LPS dripped nasally. IL-8, IL-1β, plasminogen activator inhibitor-1, monocyte chemoattractant protein-2, and the expressions of CCR1 and CCR2b were studied by using Realtime-RT-PCR, ELISA and cyto-flowmetry.

体外实验选用A549细胞系,应用LPS(10μg/mL)刺激合并RS504393(10μg/mL)治疗6 h后,流式细胞仪技术检测CCR1和CCR2的表达,ELISA法检测细胞培养上清液内白介素-8的浓度;体内实验选用C57BL/6J小鼠,腹腔注射RS504393(5 mg/kg)预处理30 min后经鼻滴入JPS(5 mg/kg),LPS刺激4 h后收集BALF和肺脏标本,计数BALF内细胞总数,应用BCA法检测BALF内蛋白浓度,Realtime-RT PCR和ELISA法检测BALF和肺脏IL-1β、凝血酶原激活物抑制物-1和单核细胞趋化蛋白-2的表达。

At last, preliminary research on the stability of NEA photocathode has been made.

第五章重点研究NEA光电阴极的激活工艺。

The development of activation and evaluation system is necessary for NEA photocathode research.

激活评估系统的研制成功为进行NEA光电阴极评估工作做好了充足准备工作。

The stability of NEA GaAs photocathode in vacuum chamber is still a problem in dispute.

目前,对GaAs阴极激活稳定性的影响因素的认识仍然存在分歧。

Conclusion]Needling in GB34 and the sham point had a certain degree of difference in the activation of cerebral functional regions.

结论]针刺阳陵泉和非穴对于脑部功能区的激活方面有着一定的差异。

That taurine may therefore activate non-synaptic GlyR affected parts of the development of neocortex.

因此推测牛磺酸可能通过激活非突触部位GlyR影响新皮质的发育。

Objective To study the uPA level in the neoplastic tissue and peripheral blood of bladder cancer patients.

目的 了解尿激酶型纤溶酶原激活剂与膀胱肿瘤恶性程度及浸润深度之间的关系。

At pre-operation, post-operation 6 h, 3 d and 7 d detect the leave of plasm prethrombotic state molecular marker tissue factor, tissue factor pass inhibitory, thrombus precursor protein, plasminogen activator inhibitory-1(PAI-1), P-Selectin, Thrombin-Antithrombin complexes, D-dimer with ELISA, transmission immunity nephelometer. Results Malignant tumor patients, the levels of plasma TF, TpP, D-D in 6 h and 3 d of post-operation rose to peak value.

分别于术前、术后6 h3、d和7 d用ELISA、透射免疫比浊法检测其血浆血栓前状态分子标志物D-二聚体(D-dimer, D-D)、血栓前体蛋白(thrombus precursor protein, TpP)、凝血酶抗凝血酶复合物(thrombin-antithrombin complexes, TAT)、组织因子(tissue factor, TF)、P选择素(P-Selectin, P-S)、组织因子途径抑制物(tissue factor pass inhibitory, TFPI)、纤溶酶原激活物抑制物1(plasminogen activator inhibitory-1, PAI-1)的水平。

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In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

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