激活

PKC activator PMA simulated the effects, but chelerythrine diminished the 〓 current to the near control level in the HPC cells, suggesting the upregulation of 〓 channels was related to PKC activation, and upregulation of 〓 channels in the HPC cells was also due to PKC activation.

PKC激动剂PMA具有同样作用，而Chelerythrine则能够抑制预处理的这种作用。提示〓通道的上调与PKC的激活有关，而且HPC对〓通道的上调作用也是通过PKC的激活起作用的。

However, dexamethasooe did not seem to affect the sustained current and the sustained component of the biphasic current induced by ATP. The in hibitory effect of dexamethasonc on ATP induced currents was blocked by glucocorticoid receptor antagonist RU38486 (10μmol/L) and protein kinase A inhibitor H-89 (10μmol/L), but not by G protein inhibitor GDP-β-S (0.2mmol/L) and protein kinase C inhibitor chelerythrine chloride (10μmol/L).

地塞米松对ATP激活电流的快速抑制作用可被糖皮质激素受体拮抗剂RU38486(10μmol/L)、蛋白激酶A抑制剂H-89(10μmol/L)阻断，而G蛋白激活抑制剂GDP-β-S(0.2mmol/L)、蛋白激酶C抑制剂Chelerythrine chloride(10μmol/L)对地塞米松的快速抑制作用无明显影响。

Metal ions of Mn2+ stimulate the ChoA activity and Ca2+ significantly stimulate the ChoB activity, while Cu2+, Fe3+, and Ag+ inhibited them.

酶A的活性能够被Mn~(2+)激活，酶B的活性则能够被Ca~(2+)激活，Cu~(2+)，Fe~(3+)和Ag~+则对两种酶的活性都有抑制作用。

In our study, we also observed the different influence between TTB-USA and RFCA on blood coagulable states (by examining the change ofα-granule membrane protein、Tissue type plasminogen activatior、Plasmingen activator inhibitor-1)、 endothelium function (by examining the change of endothelin、nitric oxide) and myocardial injury (by examining the change of creatine kinase、MB isoenzy of creatine kinase and cardiac troponin T).

为观察超声消融与射频消融对血凝状态、内皮功能及心肌损伤的影响，进一步对超声消融的安全性进行评价，我们在插管前、插管后、消融后即刻、消融后30min及48小时5次抽静脉血，分别测定血小板α-颗粒糖蛋白(GMP-140)阳性表达活化血小板百分率、内皮素、一氧化氮、组织型纤溶酶原激活剂及纤溶酶原激活剂抑制物-1(PAI-1)的变化；于消融前、消融后即刻、2hr、8hr、24hr、48hr、72hr抽取静脉血，检测肌酸激酶、肌酸激酶MB同工酶及心肌肌钙蛋白T的变化。

Functions: supplement collagenic fibre and effectively restore the damaged collagenic fibre. Provide the skin with moisture and nutrition. Remove the thin wrinkle and dry wrinkle around the eyes, delay consenescence of the eye skin. Stem cell activating factors can quickly activate the dermal cells in all layers, promote the renewal of aging cells and speed up the restoring and composing of collagenic fibre and elastic fiber to restore the aging skin. HA high-effectively supplements moisture that can be maintained for a long time. Grapeseed Oil, VitE and Green Tea Extracts Liquid feature in anti-oxidation, removal of free radicals, improvement of the skin metabolism and circulation, elimination of extra moisture and toxin, recovery of skin energy and vigor. Its long time use will make your skin tight and tender, presenting a new look full of vigorous charms.

产品功效：补充胶原蛋白，有效修复受损胶原纤维，为肌肤提供水分和营养，消减眼部细纹和干纹，延缓眼部肌肤的衰老；干细胞激活素能够快速激活皮肤各层细胞，促进衰老细胞的更新，加速胶原纤维和弹性纤维的修复与合成，修复老化受损肌肤； HA 强效补水，高效保湿；葡萄籽油、 VitE 、绿茶萃取液等抗氧化、清除自由基，改善肌肤的代谢和循环，排除多余水分和毒素，回复肌肤能量与活力，长期使用，将令眼部肌肤紧致细嫩，神采奕奕。

Expression of copCD is regulated directly by the two-component response regulator CopR, which also regulates its own expression.

双元调控系统中的调控蛋白CopR不仅激活copCD表达，而且还激活copRS的表达。

Through activating the synthesis of jasmonic acid itself,aboveground application of jasmonia acid could induce the expression of Bx1,Bx9,PAL,PR-1,MPI,FPS and TPS genes,increase DIMBOA content and decrease caffeic acid content in leaves;on the other hand,the systematic induction of gene expression of Bx6,Bx9、PAL and PR-2a,increase of contents of coumaric acid and caffeic acid,and decrease of syringic acid content in the roots were related with the activating of jasmonic acid synthesis in the aboveground.

茉莉酸处理地上部是通过激活茉莉酸自身合成来诱导叶片Bx1、Bx9、PAL、PR-1、MPI、FPS和TPS基因的表达、增加叶片丁布含量及降低咖啡酸含量的，同时系统诱导根系Bx6、Bx9、PAL和PR-2a基因表达、增加香豆酸和咖啡酸含量以及降低丁香酸含量则与激活地上部茉莉酸自身合成相关。

BBR can activate extracellular-signal regulated kinase signaling pathway in liver cells very rapidly and dose dependently in vitro.

BBR在体外能迅速激活细胞的胞外信号调节激酶信号转导途径，ERK的激活作用在时间上提前于LDLR的表达增加。

The different factors involved in the process of the folding and activation of the microbial lipase are reviewed in this article,including lipase-specific foldase,lipase activation factor,prosequence,calcium ion and disulphide bond.

对微生物脂肪酶活性构像的形成和激活机制进行深入研究，有助于我们更好地了解脂肪酶的结构和功能，为脂肪酶基因的大量表达和体外定向进化奠定基础。本文主要综述了作为脂肪酶结构成分的多种因子在脂肪酶活性构像形成、激活及稳定中的作用。具体催化反应体

Multiple factors participated in the process of secondary brain edema and nerve injuries,such as the hydrostatic pressure during formation of the hematoma and clot retraction, activation of blood coagulation cascade, generation of thrombin,erythrocytolysis and the toxicity of hemoglobin, the activation of the complement system, space-occupying effects, rupture of the blood-brain barrier,secondary ischemia around the hematoma, inflammatory reaction of the neurons around hematoma and cell apoptosis.

脑出血后继发水肿及神经损害有多种因素参与，血肿形成过程中的流体静力压和血凝块的回缩、凝血瀑布的激活、凝血酶的产生、红细胞溶解和血红蛋白的毒性、补体的激活、占位效应、血脑屏障的破坏、血肿周围继发缺血、血肿周围组织神经细胞炎症反应及细胞凋亡等。

John Robbins lives with his family in Santa Cruz, California.

约翰罗宾和家人居住在加利福尼亚州的圣克鲁斯县。

The international background is mainly the economic ties among different nations tented to be widen and deepen at the peace and development times.

国际背景主要是和平与发展时代条件下的世界各国经济贸易联系的日益加深。