激动

She enthused."I have no way of describing how excited I am."

她很激动。&我无法形容我现在有多激动。&

Whether if you vs. of she totally it agree, she then will 258 ten thousand picture if disagree you, Show you understand if you make what atmosphere control very much romantic at all then, You will certainly love veteran if, you at all enough ripe if you go and let she often too then, She will feel irritated and oily but if you go and look for she, she will blame if any of generals wearing it you cheat emotional you of she, She will say that you are that what the play-boy wore is a bit more tattered , then you are a stolid fellow if you are jealous, She will it says to be incorrect like this but if totally jealous you, she again can think you like she you if you attempt and flirt to her at all, She will think you respect she but if well-behaved you, she again can think you like if she you come late one minute, She will complain if oneself late she how tired and more bitterly does it wait for, she will say girl it dates late to be natural if you go and look for friend of you, She will say if your picture copycat is her, she will talk about \" oh, this is very natural, Girl \" if you kiss she quickly, she will very much cold and detached if you kiss too much to say you everywhere like this, She will yell that you ate her bean curd if you have not looked after her while crossing the road, You lack morals if you look after she cross the road, she again can say this whether if trick you of man stare at a certain woman carefully then, She will criticize you to flirt and stare at to girl student she think other man everywhere, She will say that they will just appreciate if you speak with her, she hopes that it is all right that so long as you listen to if you only listen attentively to, She you speak with her again Man has seen that may say : Fly to the sky, you create take these name to have simple and complicated and weaker so living beingses woman, But so intrepid to let people angry and Cupid, please tell me should how make.

是否如果你对她全部它同意， 268，000 将然后想象如果不同意你的她，让看如果那时你确实做非常浪漫的空气控制的，你理解，你当然将爱老战士，如果，你确实足够成熟你去被让她也那时经常，她感到将激怒和油性但是如果你去寻找她，她责备将如果将军中任何人穿它你骗取易激动你她，她将说你是花花公子穿的是有点多变得破烂，然后如果你妒忌，你是一个不易激动的人，她将错误象这样但是如果全部妒忌你说，再次的她认为能你喜欢她你你试图并且确实给她调情，她认为将，你尊重她但是如果行为端正你，她再次认为能你喜欢如果她你为一分钟晚来，她抱怨将如果自己后她多疲倦和更极其做它等，她将说女孩日期是自然的后期你去寻找你的朋友，她将说是否你的照片盲目模仿者是她，她将谈论\&噢，这非常自然，女孩\&如果你吻她迅速，她将很多冷和分开你吻那么多不会象这样到处说你，她将号叫如果你在穿过道路时没照看她，你吃她的豆腐，你缺乏品行你照看如果她穿过道路，再次的她说能这是否如果计谋你人那时仔细注视一定妇女，她将批评你调情并且对她到处认为其他男人的女生注视，她将说他们将感激是否你与她谈话，她希望它好那，只要你听是否你只注意听，她你再次与她讲男人已经看见那可以说：飞往天空，你创造花费这些个名字喝简单和错综复杂和更弱的如此活着的生物妇女，但是如此无畏忿怒和丘比特，请我怎样挣。

What part of the visit excited you most?

最令人激动的是什么？使人激动的；令人兴奋的

J Am Coll Cardiol,1991;17:509［15］ Shimizu A,Nozaki A,Rudy Y,et al.Onset of induced atrial flutter in the canine pericarditis model ［J］.J Am Coll Cardiol,1991,17:1 223［16］ Stevenson WG,Khan H,Sager P,et al.Identification of reentry circuit sites during catheter mapping and radiofrequency ablation of ventricular tachycardia late after myocardial infarction ［J］.

在冠状窦起搏周长为300 ms和静脉给予1 mg/kg氟卡胺后，在房扑组病例中SD2均由上至下进行性延迟，指示第二个心房波激动主要是由间隔激动沿三尖瓣环逆钟向兴奋右房游离壁所致，显示出跨界嵴传导功能性阻滞。

In this study, We typed the the gene of β〓-AR from genomic DNA of asthmatic patients and made the further analysis: The distributing condition of genetic polymorphisms at positions 16 and 27 in β〓 AR coding region and at position 19 in 5'Leader Cistron (5'LC) among southwest Chinese asthmatic population; The relationship between the each polymorphisms at the above three positions and the asthmatic phenotypes (FEV〓 or nocturnal asthma); The effect of each polymorphisms at the above three positions on bronchodilator responsiveness induced by β〓- agonists(initial bronchodilator response, pharmaco-dynamic); The relationship between the haplotypes of polymorphisms in the 5'LC or in positions 16, 27 of β〓AR coding block and asthmatic phenotypes or bronchodilator responsiveness induced by β〓-agonists.

实验通过对哮喘人群的β〓-AR基因进行分型，探讨：β〓-AR编码区16、27位点及5'前导肽(5'LeaderCistron，5'LC)19位点遗传多态性在中国西南地区哮喘人群中的分布情况；三个位点多态性与哮喘临床表现型的关系；三个位点多态性对β〓受体激动剂反应性(支气管舒张反应，舒张反应动力学)的影响；16、27位点及5'前导肽19位点遗传多态性单倍型与哮喘临床表现型及β〓受体激动剂反应性的关系。

In control experiments, 10 nM of Tyr-D-Ala-Gly-Me-Phe-Gly-ol, a synthetic enkephalin and specific mu agonist, activatedthe MOR-1, whereas 20 mM of glucose had no effect.

结果为对照实验中， 10 nM 的 Tyr-D-Ala-Gly-Me-Phe-Gly-ol（一种人工合成的脑啡肽，为μ受体特异性激动剂）可激动 MOR-1；而20 mM 的葡萄糖却并没有作用。

The present study investigated the effects of a specific COX-2 inhabitor(NS-398) and a selected PPARγagonist on the proliferation and apoptosis of pancreatic cancer SW1990 cell line to examine whether the two non-celltoxicity agents have synergistic anticancer role, so as to establish the experimental bases for application PPARγagonist associating with specific COX-2 inhabitor in treating pancreatic cancer.

本课题研究特异性COX-2抑制剂NS-398和PPARγ激动剂罗格列酮对人胰腺腺癌细胞系SW1990增殖、凋亡的影响，旨在明确两种非细胞毒性药物对胰腺癌有无协同抗癌作用，为临床联合应用特异性COX-2抑制剂和PPARγ激动剂防治胰腺癌提供实验依据。

The effects and mechanism of GABAergic neurons, NOergic neurons, opioid peptide and cyclic adenosine monophosphate in the nucleus reticularis thalami on sleep-wakefulness cycle of rats and the effects and mechanism of the 5-HTergic nerve fibers project from the nucleus raphes dorsalis to RT on sleep-wakefulness cycle of rats were investigated with the methods of brain stereotaxic, nucleus spile, microinjection and polysomngraphy.1. The effects of GABAergic neurons in RT on sleep-wakefulness cycle of rats1.1 Microinjection of 3-mercaptopropionic acid (3-MP, a kind of glutamate decarboxylase inhibitor) into RT. On the day of microinjection, sleep only decreased a litter. On the second day, sleep marked decreased and wakefulness marked increased. On the third and fourth day, sleep and wakefulness stages resumed to normal.1.2 Microinjection of gamma-amino butyric acid (GABA 1.0μg) into RT enhanced sleep and reduced wakefulness compared with control; while microinjection of L-glutamate (L-Glu, 0.2μg) decreased sleep and increased wakefulness; microinjection of bicuculline (BIC, 1.0μg), a GABAA receptor antagonist, enhanced wakefulness and reduced sleep; microinjection of baclofen (BAC, 1.0μg), GABAB receptor agonist, had the same effects as GABA.2. The effects of NOergic neurons in RT on sleep-wakefulness cycle of rats2.1 Microinjection of L-arginine (L-Arg, 0.5μg) into RT decreased sleep compared with control, but there were on statistaical difference between L-Arg group and control; while microinjection of sodium nitroprusside (SNP, 0.2μg), a NO donor into RT, sleep marked decreased and wakefulness marked increased. Microinjection of nitric oxide synthase inhibitor, N-nitro-L-arginine (L-NNA, 2.0μg) into RT enhanced sleep and reduced wakefulness.2.2 After simultaneous microinjection of L-NNA (2.0μg) and SNP (0.2μg) into RT, SNP abolished the sleep-promoting effect of L-NNA compared with L-NNA group; after simultaneous microinjection of L-NNA (2.0μg) and L-Arg(0.5μg) into RT, we found that L-NNA could not blocked the wakefulness-promoting effect of L-Arg.3. The effects of opioid peptide in RT on sleep-wakefulness cycle of rats3.1 Microinjection of morphine sulfate (MOR, 1.0μg) into RT increased wakefulness and decreased sleep compared with control; while microinjection of naloxone hydrochloride (NAL, 1.0μg), the antagonist of opiate receptors, into RT, enhanced sleep and reduced wakefulness.3.2 After simultaneous microinjection of MOR (1.0μg) and NAL (1.0μg) into RT, the wakefulness-promoting effect of MOR and the sleep-promoting effect of NAL were not observed compared with control.4. The effects of cAMP in RT on sleep-wakefulness cycle of rats Microinjection of cAMP (1.0μg) into RT increased sleep and decreased wakefulness compared with control; microinjection of methylene blue (MB,1.0μg) into RT enhanced sleep and reduced wakefulness compared with control.5. The effects of the 5-HTergic nerve fibers project from DRN to RT on sleep-wakefulness cycle of rats5.1 When L-Glu (0.2μg) was microinjected into DRN and normal sodium (NS,1.0μg) was microinjected into bilateral RT. We found that sleep was decreased and wakefulness was increased compared with control; when L-Glu (0.2μg) was microinjected into DRN and methysergide (MS,1.0μg), a non-selective 5-HT antagonist, was microinjected into bilateral RT, We found that sleep was enhanced and wakefulness was reduced compared with L-Glu group.5.2 When p-chlorophenylalanine (PCPA, 10μg) was microinjected into DRN and NS (1.0μg) was microinjected into bilateral RT, We found that sleep was increased and wakefulness was decreased compared with control; microinjection of 5-hydroxytryptaphan (5-HTP, 1.0μg), which can convert to 5-HT by the enzyme tryptophane hydroxylase and enhance 5-HT into bilateral RT, could block the effect of microinjection of PCPA into DRN on sleep-wakefulness cycle.

本研究采用脑立体定位、核团插管、微量注射、多导睡眠描记等方法，研究丘脑网状核(nucleus reticularis thalami，RT)中γ-氨基丁酸(gamma-amino butyric acid ，GABA)能神经元、一氧化氮(nitrogen monoxidum，NO)能神经元、阿片肽类神经递质、环一磷酸腺苷(cyclic adenosine monophosphate，cAMP)及中缝背核(nucleus raphes dorsalis，DRN)至RT的5-羟色胺(5-hydroxytryptamine，5-HT)能神经纤维投射对大鼠睡眠-觉醒周期的影响及其作用机制。1 RT内GABA能神经元对大鼠睡眠-觉醒周期的影响1.1大鼠RT内微量注射GABA合成关键酶抑制剂3-巯基丙酸(3-MP，5μg)，注射当天睡眠时间略有减少，第二日睡眠时间显著减少，觉醒时间明显增多，第三、四日睡眠和觉醒时间逐渐恢复至正常。1.2大鼠RT内微量注射GABA受体激动剂GABA( 1.0μg)后，与生理盐水组比较，睡眠时间增加，觉醒时间减少；而RT内微量注射L-谷氨酸(glutamic acid， L-Glu， 0.2μg)后，睡眠时间减少，觉醒时间增加；RT内微量注射GABAA受体阻断剂荷包牡丹碱(bicuculline，BIC，1.0μg)后，睡眠时间减少，觉醒时间增加；RT内微量注射GABAB受体激动剂氯苯氨丁酸(baclofen，BAC，1.0μg)后，产生了与GABA相似的促睡眠效果。2 RT内NO能神经元对大鼠睡眠-觉醒周期的影响2.1大鼠RT内微量注射NO的前体L-精氨酸(L-Arg，0.5μg)后，与生理盐水组对比，睡眠时间略有减少，但无显著性意义；而RT内微量注射NO的供体硝普钠(Sodium Nitroprusside，SNP，0.2μg)后可明显增加觉醒时间，缩短睡眠时间；微量注射一氧化氮合酶抑制剂L-硝基精氨酸(L-arginine，L-NNA，2.0μg)后，引起睡眠时间增多，觉醒时间减少。2.2大鼠RT内同时微量注射L-NNA(2.0μg)和SNP(0.2μg)后与L-NNA组比较发现SNP逆转了L-NNA的促睡眠作用；RT内同时微量注射L-NNA(2.0μg)和L-Arg(0.5μg)后，与L-NNA(2.0μg)组比较发现L-Arg可以增加觉醒而缩短睡眠，其促觉醒作用未能被NOS的抑制剂L-NNA所逆转。3 RT内阿片肽对大鼠睡眠-觉醒周期的影响3.1大鼠RT内微量注射硫酸吗啡(morphine sulfate，MOR，1.0μg)后与生理盐水组对比，睡眠时间减少而觉醒时间增加； RT内微量注射阿片肽受体拮抗剂盐酸纳洛酮(naloxone hydrochloride，NAL，1.0μg)后与生理盐水组比较，睡眠时间增加而觉醒时间减少。3.2大鼠RT内同时微量注射MOR(1.0μg)和NAL(1.0μg)后，与生理盐水组对比，原有的MOR促觉醒效果和NAL的促睡眠效果都没有表现。4 RT内环一磷酸腺苷信使对大鼠睡眠-觉醒周期的影响大鼠RT内微量注射cAMP(1.0μg)后与NS(1.0μg)组比较，睡眠时间增多而觉醒时间减少；RT内微量注射亚甲蓝(methylene blue，MB，1.0μg)后，与NS组比较，睡眠时间增多而觉醒时间减少。5中缝背核投射到丘脑网状核的5-羟色胺能神经纤维对大鼠睡眠-觉醒周期的影响5.1大鼠DRN内微量注射L-Glu(0.2μg)，同时在双侧RT内微量注射NS (1.0μg)后，与对照组(DRN和双侧RT注射NS， 0.2μg)比较，睡眠时间减少，觉醒时间增多；大鼠DRN内微量注射L-Glu(0.2μg)，同时在双侧RT内微量注射二甲基麦角新碱(methysergide， MS， 1.0μg )后，与对照组(DRN注射L-Glu 0.2μg，双侧RT注射NS 1.0μg)比较，睡眠时间增多，觉醒时间减少。5.2大鼠DRN内微量注射对氯苯丙氨酸(p-chlorophenylalanine，PCPA，10μg)，同时在双侧RT内微量注射NS (1.0μg)后，与对照组(DRN和双侧RT注射NS， 1.0μg)比较，睡眠时间增多，觉醒时间减少；大鼠DRN内微量注射PCPA(10μg)，产生睡眠增多效应后，在双侧RT内微量注射5-羟色胺酸(5-hydroxytryptaphan ， 5-HTP， 1.0μg )后，与对照组(DRN注射PCPA 10μg，双侧RT注射NS 1.0μg)比较，睡眠时间减少，觉醒时间增多。

The P wave duration and P 2R interval were increased while pacing at right atrial appendage 1 The activation time from pacing site to His bundle and coronary sinus was the longest in pacing at right atrial appendage , while the activation time in pacing at Koch triangle , Koch triangle with high right atrium and biatria was significantly shorter especially pacing at Koch triangle and Koch triangle with high right atrium1 There were no significant differences in right atrium pressure among all pacings1 Conclusion It is suggested that Koch triangle pacing could probably replace high right atrial with coronary sinus pacing and biatrial pacing 1

从心房激动顺序分析，右心耳起搏时，激动传至希氏束区及冠状窦区的时间最长，而 Koch三角、Koch三角+高位右房及双房起搏时则较短，尤其是 Koch三角、Koch三角+高位右房起搏缩短更明显。另外，不同部位、不同方式起搏时右心房压力无差异。结论 Koch三角起搏在某种程度上可替代高位右房+冠状窦起搏及双房起搏。

But she kept calm amid all these excitements.

但她在所有激动激动面前保持镇静。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了