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By 1935 physicians were beginning to notice that some patients who had asbestosis also were victims of lung cancer.

在20世纪初,研究人员开始注意到石棉矿工人和附近居民有大量的肺病和过早死亡的病例。1906年,对一名石棉工人的尸体进行解剖,发现他的肺部呈纤维化,这是首次确定与石棉有关的死亡案例。1928年,一位医生提出,长期吸入石棉粉尘能对肺部造成纤维化创伤,导致"石棉沉着病",潜伏期能长达15年。1935年,医生们开始注意到,有些石棉沉着病的患者同时也患有肺癌。

Methodssmear 0.25% croton oil\acetone ag on the back of kunming mice,and observe the growth condition of papilloma,then record the quantity of tumor-bearing mice and the quantity of tumor in each mice.results20-ginsenoside rh2 prolonged the incubation of tumor, reduced the quantity of tumor-bearing mice and decreased the amount of tumor in each mice.conclusion20ginsenoside rh2 has obvious anti-papilloma effect on the mice skin.

结果20-人参皂苷rh2对小鼠皮肤乳头状瘤有明显的抑制作用,可使肿瘤发生潜伏期延长,使化学致癌物诱发的荷瘤动物数明显减少,每鼠荷瘤数显著下降。结论20r 人参皂苷rh2在预防癌症的发生和发展方面有重要的作用,也是很有前景的新型抗癌药。

The onset latencies of the antagonist trunk muscles relative to the deltoid muscle were analyzed to determine the effects of group, target height and load.

躯干拮抗肌的起始潜伏期与三角肌的关系取决于试验的组别,目标的高度及负荷的不同。

Gene mutations were detected in 25 patients and a 18-year-old girl among 16 families. Trinucleotide repeats of CAG were 73~79. The fragments of abnormal alleles were 380~402bp, and all patients were heterozygous. The copy numbers of normal alleles were 18~40, fragments from 202~270bp. SCV reduction was much obvious compared to MCV, MCV and SCV in lower limb ?ere much more slow than that in upper's. BAEP, VEP were also delayed in latency. The anticipation in parental sex bias were much more obvioius than that in matental's. Cerebellar ataxia was most severe, the next were dysarthria and bulging eyes. Amytrophy was seen only in bed ridden patients. Cerebellar atrophy was more severe than brain stem, cord atrophy was n't observed in all MJD.

结果检出10个家系25例病人及1例症状前18岁女孩有MJD基因突变,CAG三核苷酸重复73~79次,异常等位基因片段长380~402bp,均为杂合子;正常人CAG三核苷酸重复18~40次,等位片段长200~270bp,电生理发现MJD的SCV减慢比MCV明显,而下肢的MCV、SCV又较上肢明显,BAEP、VEP均有不同程度的潜伏期延长或波的异常;MJD的父亲遗传早于母亲,进展也较块,临床以小脑性共济失调为突出症状,其次为构音障碍、突眼等,肌肉萎缩仅见于晚期病人;MRI示小脑萎缩较明显,脑干萎缩并不严重,未见明显的颈髓萎缩。

RESULT: In vitro, TISE at the concentrations of 760 and 380 mgL-1 had significant antagonistic effect on the normal bronchus slice contraction caused by histamine as well as on the sensitized bronchus slice contraction caused by egg albumin, but had no effect on the contraction caused by acetylcholine. in vivo, TISE at doses of 25 and 18 mgkg-1 could significantly prolong the latent period of expiratory dyspnea, tic and falling down caused by egg albumin in sensitized guinea pigs.

结果:离体实验,TISE 760,380 mgL-1对组胺致正常豚鼠气管片的收缩具有对抗作用,对卵白蛋白所致的致敏豚鼠支气管平滑肌收缩有极显著的抑制作用(P<0.01),而对乙酰胆碱所致气管片收缩无明显影响;整体实验,TISE 25,18 mgkg-1可显著延长卵白蛋白所致的致敏豚鼠呼吸困难、抽搐和跌倒的潜伏期(P<0.01)。

This latent period between exposure to the plant and appearance of the rash may be as short as four hours or as long as 10 days, depending on individual sensitivity and the amount of plant contact.

这一个潜伏期在对植物的暴露之间和轻率者的外表可能是像四小时一样的短或像 10 天一样的长,仰赖个别的敏感和大的植物连络。

The virus is relatively slow moving and the average time of incubation from exposure to brain involvement is between 3 to 8 weeks in dogs, 2 to 6 weeks in cats, and 3 to 6 weeks in people.

该病毒是相对缓慢移动的平均时间的潜伏期接触到大脑的参与是3至8周的实验研究,第2至6周的猫,和3至6周的人。

Results: Among 32 tested MNs, depolarizing responses(excitatory postsynaptic potential, EPSP) were elicited by cVLF stimulation in 21 MNs, hyperpolarizing response (inhibitory postsynaptic potential, IPSP) in 1 MN, and IPSP preceded by EPSP in 4 MNs. The cVLFEPSPs were stimulus intensity-dependent, and could be abolished by low Ca(superscript 2+)/high Mg(superscript 2+) solution. compared with iVLF-EPSPs, cVLF-EPSPs showed longer latency (P.001). The cVLF-IPSP presented with membrane potential-dependent property and was eliminated by the perfusion of picrotoxin (30 μmol/L) and strychnine (1.0 μmol/L).

结果:在32个测试的MNs,观察到cVLF电刺激可在21个MNs上诱发去极化反应(即cVLF性兴奋性突触后电位,cVLF-EPSP),在1个MN上诱发超极化反应(即cVLF性抑制性突触后电位,cVLF-IPSP),在4个MNs上诱发cVLF-EPSP后复合有cVLF-IPSP的反应。cVLF-EPSP具有刺激强度依赖性、被低钙高镁溶液取消的特性,与i VLF性EPSP相比,有潜伏期较长的特点(P.001)。cVLF-IPSP呈膜电位依赖性,并被印防己毒素(30μmol/L)及士的宁(1.0μmol/L)取消。

The results shoed that the statistical prolongation of AP(N1) latency in respouse to click and tone bursts after exposure could used as an ideal index of early assessment of PTS.

结果发现,暴露后对短声及各频率短纯音反应的AP(N1)潜伏期均出现统计学意义的延长者,可作为预测永久性阈移的一项较理想的指标。

At a low temporal frequency 5Hz,peak responses occured in response to the maximum(in on-center cells or minimum (in off-center cells) luminances of light modulation with an identical delay.

在低的刺激频率(5Hz)下,给光中心和撤光中心细胞的反应峰值延迟时间(相对于光调制信号的最大和最小值)也相同,表明它们具有相同的反应潜伏期。

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Finally, according to market conditions and market products this article paper analyzes the trends in the development of camera technology, and designs a color night vision camera.

最后根据市场情况和市面上产品的情况分析了摄像机技术的发展趋势,并设计了一款彩色夜视摄像机。

Only person height weeds and the fierce looks stone idles were there.

只有半人深的荒草和龇牙咧嘴的神像。

This dramatic range, steeper than the Himalayas, is the upturned rim of the eastern edge of Tibet, a plateau that has risen to 5 km in response to the slow but un stoppable collision of India with Asia that began about 55 million years ago and which continues unabated today.

这一引人注目的地域范围,比喜马拉雅山更加陡峭,是处于西藏东部边缘的朝上翻的边框地带。响应启始于约5500万年前的、缓慢的但却不可阻挡的印度与亚洲地壳板块碰撞,高原已上升至五千米,这种碰撞持续至今,毫无衰退。