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Between P14 and P21,CIAPIN1 immunoreaction in the brain,heart and liverbecame much lower. However,between P21 and P28,CIAPIN1 immunoreactionin the heart,brain,liver and skeletal muscle became much lower,while with thekidney development,CIAPIN1 immunoreaction in the kidney became higher. Invarious tissues from adult mouse,CIAPIN1 immunoreaction could be seen incardiac muscle cell,brain,hepatocyte,epithelium of renal tubule,skeletal muscle,lung tissue,gastric mucosa and gland,acinus lienalis.2. Distribution of CIAPIN1 in normal fetal and adult human tissuesTo reveal the possible physiological role of CIAPIN1,we examined theexpression and distribution of CIAPIN1 in fetal and adult human tissues usingimmunohistochemistry. We found that CIAPIN1 was ubiquitously distributed infetal and adult tissues,and was localized in both the cytoplasm and the nucleus.

然而,在3个月大的成年鼠中,CIAPIN1阳性反应物在心、脑、肝和肾小管中的表达强度要低于P28小鼠;但CIAPIN1阳性反应物在成年鼠骨骼肌中较P28小鼠高。2、CIAPIN1蛋白在人5个月胚胎及成人多器官组织内的表达在人5月胚胎多器官组织中,CIAPIN1阳性反应物见于心脏、胆囊单层柱状上皮和粘膜、结肠粘膜、小肠粘膜和绒毛、肝脏、直肠腺体、胃粘膜、肾上腺束状带、甲状腺滤泡、脾索、胸腺小叶间隔、皮肤真皮层和汗腺、睾丸白膜和间质、脑组织内神经元和神经胶质、肺小支气管和肺泡、骨骼肌、肾脏皮髓质和肾小管、子宫内膜、胰腺腺泡和胰岛、卵巢、输卵管粘膜等绝大多数组织细胞。

The ideal bleb, he said, is a bleb that is diffuse and hypervascular but not avascular.

他说理想的滤泡有渗透性,多血管而非无血管。

Aberrant filtering bleb morphology also may be cystic and avascular as well as prone to spontaneous leakage.

异常的滤泡形态除了有自发泄漏倾向外,也可能会出现囊状及无血管。

In ovary, PNA receptors appeared in the oocyte cytoplasm of second phases of oogenesis; the positive granules gradually increased from third to forth phases, and they exhibit a maximum expression before vitellogennic stage in cytoplasm of oocyte; from vitellogennic stage to chorionation stage, the positive granules gradually reduced. Binding sites on follicle cells were changed with their morphological variation in every stage of oogenesis.The staged and specific expression of oncogene c-kit, the tyrosine-kinase receptor, is closely related with gametogenesis.

2在中华蚱蜢卵子发生的早期,PNA受体是由卵母细胞自身合成;在卵黄发生前的准备时期,卵母细胞质中的PNA受体一部分来源于自身合成,另一部分则来源于滤泡细胞,而糖复合物的大量出现可能直接与卵黄发生有关;卵黄发生期PNA受体的减少可能是在卵黄物质形成中部分发生了修饰;卵黄和卵壳的相继形成过程中,阳性反应的出现说明PNA受体参与了卵黄膜及卵壳的形成,而这些受体物质是由滤泡细胞分泌的。

We also have observed some organs pathological changes of juvenile Jian Carp, such as pancreas acinous gland and zymogen granules of acinous gland cell disappearing, intercellular substance hyperplasia and inflammatory cells soakage, hepatatrophia, liver cell granular or vacuolar degeneration and necrosis, karyolysis or pyknosis, glycogen granules decreasing, metanephros atrophy, metanephric canaliculus epithelium granular or vacuolar degeneration and necrosis, mitochondrion swelling and mitochondrion cristae disappearing, karyolysis, distal convolutal tubule microvilli desquamating, spleen marrow cell degeneration and necrosis, intercellular substance of spleen hyperplasia, spleen atresia, blood corpuscle disappearing.

后肾土黄色、淡褐色或苍白色,肾小管上皮细胞肿胀、颗粒或水泡变性、坏死,细胞内有大量血细胞流出,线粒体肿胀,嵴结构消失,细胞核溶解,肾间质甲状腺滤泡和拟淋巴细胞增生,远曲小管微绒毛脱落、管道细胞界限不清。心脏肌纤维肿胀、颗粒或空泡变性,严重的肌纤维溶解、变细或断裂,肌纤维间水肿、炎性细胞浸润,部分心肌细胞核浓缩。脾脏暗褐色,脾髓质细胞变性、坏死,拟淋巴细胞明显减少,淋巴细胞岛少见、岛中细胞成份减少,黑素巨噬细胞中心减少、体积缩小,脾脏网状基质水肿,脾窦闭锁,血细胞减少。

"Spermatogenesis is a long and complex process controlled by multiple interacting mechanisms, and there is a general consensus on the need for FSH in the regulation of this process," write Carlo Foresta, MD, and colleagues from the University of Padova in Italy.

精子的生成是一个很长且很复杂的过程,它是由多种彼此作用的机制控制的,在这个过程中,一般都一直需要卵滤泡刺激素的作用,」意大利Padova大学的Carlo Foresta医师及其同事写道:「从睾丸细胞学分析的结果可以看到,采用100 IU剂量的重组人卵滤泡刺激素隔日使用,以刺激精子产生的过程,同时,还可以增加射出的精子的数目,并加强抑制素B的分泌。

PFOS induced thyroid follicle cell hyperplasia, the depletion of colloid and even vacuolation with dose-effect relationships after 6 months exposure. Malformations of gonad with intersex, pearling and segmental aplasia were found in all treatment groups. The gonad with intersex showed a testis tissue with a female ovarian cavity like structure.

6个月后,PFOS组甲状腺出现滤泡上皮细胞增生、胶质减少甚至空泡化等现象,且随着PFOS浓度的增加而加重;各组幼蛙性腺出现间性、睾丸珍珠状和先天性萎缩等畸形现象,外观为间性的性腺主要表现为睾丸组织中产生类似雌性个体的卵巢腔。

The preparation of the membrane is that the phthalazine polyether-sulfone-ketone polymer is mixed with chloroform, Ethanol or butanol according to certain quality proportion; after the magnetic stirring, the evenly mixed casting solution is obtained, filtered and carried out with vacuum deaeration; The casting solution is scraped into membrane of certain thickness on the non-woven fabric by adopting the scraper; the membrane is standed for 24 hours in the air of certain humidity and temperature to obtain the plate ultrafiltration membrane of phthalazine polyether-sulfone-ketone.

本发明公开了属于高分子膜分离技术领域的一种二氮杂萘聚醚砜酮类聚合物平板超滤膜的制备方法,所述膜的制备方法为:用二氮杂萘聚醚砜酮类聚合物与氯仿、无水乙醇或正丁醇按照一定的质量比混合,磁力搅拌后得到混合均匀的铸膜液,过滤并真空脱泡;将铸膜液采用刮刀在无纺布上刮制成一定厚度的膜,该膜在一定湿度和温度的空气中静置24h后即得到二氮杂萘聚醚砜酮类平板超滤膜。

Methods:Phacoemulsification and implantation with foldable and rigid intraocular lens were performed on 41 eyes with a preexisted filtering bleb,and a clear corneal or scleral tunnel incision was selected.

32例 (4 1只眼)抗青光眼滤过术后的白内障患者,采用上方透明角膜隧道切口和避开滤过泡的巩膜隧道切口行白内障超声乳化吸除,植入折叠式人工晶状体 2 4只眼,硬性人工晶状体 17只眼。

METHODS: Thirtyfour patients (35 eyes) underwent the needle revision of the dysfunctional blebs with MMC at clinic visits in 322 weeks after trabeculectomy and observed blebs reformation and the descent of intraocular pressure followed up for more than 6 months.

滤过泡的瘢痕化、包裹均可导致手术失败,眼压再次上升进而对视神经造成不可逆的损害。其主要原因是巩膜瓣、Tenon's囊和结膜之间的粘连愈合而不是滤过口的阻塞[3]。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

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