滤泡

Between P14 and P21,CIAPIN1 immunoreaction in the brain,heart and liverbecame much lower. However,between P21 and P28,CIAPIN1 immunoreactionin the heart,brain,liver and skeletal muscle became much lower,while with thekidney development,CIAPIN1 immunoreaction in the kidney became higher. Invarious tissues from adult mouse,CIAPIN1 immunoreaction could be seen incardiac muscle cell,brain,hepatocyte,epithelium of renal tubule,skeletal muscle,lung tissue,gastric mucosa and gland,acinus lienalis.2. Distribution of CIAPIN1 in normal fetal and adult human tissuesTo reveal the possible physiological role of CIAPIN1,we examined theexpression and distribution of CIAPIN1 in fetal and adult human tissues usingimmunohistochemistry. We found that CIAPIN1 was ubiquitously distributed infetal and adult tissues,and was localized in both the cytoplasm and the nucleus.

然而，在3个月大的成年鼠中，CIAPIN1阳性反应物在心、脑、肝和肾小管中的表达强度要低于P28小鼠；但CIAPIN1阳性反应物在成年鼠骨骼肌中较P28小鼠高。2、CIAPIN1蛋白在人5个月胚胎及成人多器官组织内的表达在人5月胚胎多器官组织中，CIAPIN1阳性反应物见于心脏、胆囊单层柱状上皮和粘膜、结肠粘膜、小肠粘膜和绒毛、肝脏、直肠腺体、胃粘膜、肾上腺束状带、甲状腺滤泡、脾索、胸腺小叶间隔、皮肤真皮层和汗腺、睾丸白膜和间质、脑组织内神经元和神经胶质、肺小支气管和肺泡、骨骼肌、肾脏皮髓质和肾小管、子宫内膜、胰腺腺泡和胰岛、卵巢、输卵管粘膜等绝大多数组织细胞。

Japonicus and analyzed the role of animal process of oocyte during ovulation and oocyte maturation. What's more, we studied the role of microtubules and microtubule organizing center upon GV migration. The oocyte of A. japonicus connects to the follicle via animal pole process. When placed in normal sea water, ovulation started spontaneously.

利用DTT诱导刺参卵母细胞成熟，综合运用光镜、电子显微镜及激光共聚焦技术观察卵母细胞成熟过程，分析了卵母细胞表面动物极突起在卵母细胞脱滤泡中的作用，以及卵母细胞动物极突起和微管组织在生发泡移动过程中所起的作用。

"It improves bleb survival in this model without disruption of the cytoarchitecture," Dr. Lama said.

Lama博士说"它能在不破坏细胞结构的情况下促进滤泡的存活"。

After that, the survival curves are parallel, indicating similar rates of bleb failure.

此后，存活曲线是平行的，表明滤泡失败的几率一样。

The ideal bleb, he said, is a bleb that is diffuse and hypervascular but not avascular.

他说理想的滤泡有渗透性，多血管而非无血管。

We also have observed some organs pathological changes of juvenile Jian Carp, such as pancreas acinous gland and zymogen granules of acinous gland cell disappearing, intercellular substance hyperplasia and inflammatory cells soakage, hepatatrophia, liver cell granular or vacuolar degeneration and necrosis, karyolysis or pyknosis, glycogen granules decreasing, metanephros atrophy, metanephric canaliculus epithelium granular or vacuolar degeneration and necrosis, mitochondrion swelling and mitochondrion cristae disappearing, karyolysis, distal convolutal tubule microvilli desquamating, spleen marrow cell degeneration and necrosis, intercellular substance of spleen hyperplasia, spleen atresia, blood corpuscle disappearing.

后肾土黄色、淡褐色或苍白色，肾小管上皮细胞肿胀、颗粒或水泡变性、坏死，细胞内有大量血细胞流出，线粒体肿胀，嵴结构消失，细胞核溶解，肾间质甲状腺滤泡和拟淋巴细胞增生，远曲小管微绒毛脱落、管道细胞界限不清。心脏肌纤维肿胀、颗粒或空泡变性，严重的肌纤维溶解、变细或断裂，肌纤维间水肿、炎性细胞浸润，部分心肌细胞核浓缩。脾脏暗褐色，脾髓质细胞变性、坏死，拟淋巴细胞明显减少，淋巴细胞岛少见、岛中细胞成份减少，黑素巨噬细胞中心减少、体积缩小，脾脏网状基质水肿，脾窦闭锁，血细胞减少。

PFOS induced thyroid follicle cell hyperplasia, the depletion of colloid and even vacuolation with dose-effect relationships after 6 months exposure. Malformations of gonad with intersex, pearling and segmental aplasia were found in all treatment groups. The gonad with intersex showed a testis tissue with a female ovarian cavity like structure.

6个月后，PFOS组甲状腺出现滤泡上皮细胞增生、胶质减少甚至空泡化等现象，且随着PFOS浓度的增加而加重；各组幼蛙性腺出现间性、睾丸珍珠状和先天性萎缩等畸形现象，外观为间性的性腺主要表现为睾丸组织中产生类似雌性个体的卵巢腔。

Granulosa cell tumor includes many growth patterns: microfollicular, macrofollicular, insular, diffuse, trabecular, watered-silk, gyriform, cystic, luteinized et al.

粒层细胞肿瘤有多种生长构型：微滤泡型、巨滤泡型、岛状、弥漫型、梁状型、波纹型、gyriform、囊性和黄素化等。

Light and electron microscope observation of thyroid morphology, image analysis system measuring follicular epithelial cell height and follicular cavity area.

光、电镜下观察甲状腺形态，图像分析仪测量滤泡上皮细胞高度和滤泡腔面积。

Inthe whole process, the oocytes, nurse cell and follicle cell morphology change. Inoocyte yolk formation and growth, the number of its nuclear trophoblast cell nucleoli,lamphrush chromosome with a strong synthetic material; oocytes also some syntheticmaterial; follicle cells in the yolk protein synthesis, provide access to exogenous yolkprotein.

在卵子发生的整个过程中，卵母细胞、滋养细胞及滤泡细胞形态均有明显变化；在卵母细胞生长及卵黄形成期，滋养细胞核内的多核仁现象、灯刷染色体与旺盛的物质合成有关；卵母细胞本身也合成一些物质；滤泡细胞参与卵黄蛋白的合成，并为外源性卵黄蛋白提供通道。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。