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滋养细胞

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Results:PSTT is composed of only one kind of intermediate type troghoblast cells,but choriocarcinoma is composed of sytotrophoblast and syncytiotrophoblast.

结果 :PSTT的瘤细胞主要是中间型滋养细胞,而绒癌显示的是细胞滋养细胞和合体滋养细胞混合而成。

At protein level, AQP8 is expressed in placental syncytiotrophoblasts, amniotic epithelial cells, and chorion cytotrophoblasts.

在蛋白质水平显示,水通道蛋白8表达于胎盘的合体滋养细胞、羊膜上皮细胞及平滑绒毛膜细胞滋养细胞

Immunohistochemistry results revealed that AQP8 protein was expressed in placental syncytiotrophoblasts, amniotic epithelial cells, and chorion cytotrophoblasts.

免疫组织化学结果显示,水通道蛋白8表达于胎盘合体滋养细胞、羊膜上皮细胞及平滑绒毛膜细胞滋养细胞

Methods: Separate and abstract the effective components of Huangqi (Omni-Saponin、total-flavone) and Danshen (Danshen-ketone、 Danshen-Quinone). Applying L-Arginine methyl ester to pregnant rats by I. P to make Nitrogen Oxide Synthesis blocking models (uterus-placenta-fetus lacking blood and oxygen model or pregnant hypertension syndrome model). On day 12, 18 of pregnancy paunched the rats and took out the fetus and placenta/uterus. Measured the basal BP during pregnant period and BP、protein、basal activity each day. Observed placenta/deciduas ultramicroscopic structure by electron microscope and took count of languishment cells. Measured the expressive intensity of bcl-2、Bax of placental nutrient cells by SABC method.

一氧化氮合成酶阻滞剂L-精氨酸甲酯妊娠大鼠腹腔给药,制作一氧化氮合成阻滞模型(子宫-胎盘-胎儿缺血缺氧或妊娠高血压模型),妊娠第12、18天剖腹取胎、胎盘/子宫,妊娠期测基础血压,每日测血压、蛋白质量、基本生理活动;电镜观察胎盘/蜕膜超微形态结构,并进行细胞凋亡计数;免疫组化检测胎盘滋养细胞bcl-2、Bax表达强度;原位杂交法检测胎盘滋养细胞、血管内皮细胞VEGF、eNOS、iNOS、MCP-1、MMP9(基质金属蛋白酶9)mRNA表达。

Decidual tissue is a very complex and highly concordant tiny environment between mother and embryo during pregnancy, which is constituted of the variety cells such as extravi11ous trophoblast,endometrium cells, bone marrow cells, decidua l microphage,T cells and a few B cells and so on.

正常蜕膜组织是母-胎界面间一个非常复杂而又高度协调的微环境,它由多种细胞如侵袭至蜕膜的绒毛外滋养细胞(extravi11ous trophoblast,EVT)、子宫内膜源性细胞(如上皮细胞和血管内皮细胞)、骨髓源性细胞(如大颗粒淋巴细胞、蜕膜巨噬细胞、T细胞和少许B细胞)构成,这些细胞以及由这些细胞、母体和胎儿所分泌到蜕膜的细胞因子共同形成了母-胎间信息交流的平台,并对胚胎滋养细胞"有控性"侵袭、子宫内膜的免疫容受性、蜕膜化和胎盘的形成进行精细的调控。

Results The expression of ADAM19 are mainly in the cell membrane, plasma and column of cytotrophoblast; The expression of ADAM19 is mainly located on cytotrophoblast during first trimester of pregnancy, and on syncytiotrophoblast in second and third trimester.

结果ADAM19的表达主要集中在滋养细胞的细胞膜、细胞质中和细胞滋养层柱细胞中;早孕绒毛中,ADAM19表达主要集中于细胞滋养细胞膜,在晚孕期胎盘,ADAM19主要表达于合体滋养细胞膜。

Consistence to the PT-PCR result, TLR4 protein was strongly expressed at syncytotrophoblast of placenta, cytotrophoblast of chorion and epithelial cell of amnion of pregnancy complicated with syphilis by Immunohistochemistry.

TLR4在妊娠合并梅毒感染的胎盘合体滋养细胞、羊膜上皮细胞和胎膜中的平滑绒毛膜细胞滋养细胞上表达增强,与RT-PCR结果一致。

Results The artery frequency spectrum of high speed and low resistance were found in malignant trophoblastic tumors. The ulterine muscular layer in malignant trophoblastic tumor was hypervascular and the resistive index was less than 0.4. After chemotherapy, the hypervascularity decreased, RI increased higher, and β-HCG returned normal.

结果 恶性滋养细胞肿瘤子宫动脉RI值较低,为高速低阻力性动脉频谱;恶性滋养细胞肿瘤宫壁血流异常丰富,子宫肌层病灶内血管阻力指数RI.4;恶性滋养细胞肿瘤患者全身化疗取得疗效后子宫肌层血流丰富区逐渐缩小,RI呈逐渐升高趋势,血β-HCG逐渐恢复正常。

Inthe whole process, the oocytes, nurse cell and follicle cell morphology change. Inoocyte yolk formation and growth, the number of its nuclear trophoblast cell nucleoli,lamphrush chromosome with a strong synthetic material; oocytes also some syntheticmaterial; follicle cells in the yolk protein synthesis, provide access to exogenous yolkprotein.

在卵子发生的整个过程中,卵母细胞、滋养细胞及滤泡细胞形态均有明显变化;在卵母细胞生长及卵黄形成期,滋养细胞核内的多核仁现象、灯刷染色体与旺盛的物质合成有关;卵母细胞本身也合成一些物质;滤泡细胞参与卵黄蛋白的合成,并为外源性卵黄蛋白提供通道。

Compared with the sense group,the mRNA expression and the protein expression of HIF 1α and TGF 3β decreased in antisense group.

滋养细胞的多功能细胞因子TGF 3β表达,与滋养细胞增殖和分化有关,可调节滋养细胞的浸润功能。

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