溶解度

In the preformulation study, the ultraviolet spectrum and HPLC methods for the assay of α-asarone were established firstly and then the physicochemical properties, especially the octanol/water partition coefficient and the solubility in various solvent systems such as alcohol, PEG 400, IPM, octanol were examined. The prediction permeability was then compared with actual transdermal parameters obtained from the in-vitro diffusion study , and feasibility of drug transdermal absorption was then analyzed.

在制剂开发的处方前研究工作中，首先建立了α-细辛醚的紫外及HPLC分析方法，测定了药物的油水分配系数及在生理盐水、各系列浓度的乙醇、PEG400、肉豆蔻酸异丙酯、正辛醇等溶媒中溶解度；其次，确立了药物体外经皮渗透研究的方法，并考察溶媒及促渗剂(乙醇、丙二醇、肉豆蔻酸异丙酯等)对药物体外经皮渗透性能的影响，计算药物经皮渗透的各参数，根据药物的药物动力学参数，分析了药物经皮吸收的可行性。

In the preformulation studies, UV absorption characteristics, solubility and stability of the drug in the different media were determined, the physico -chemical compatibility between the drug and nine kinds of excipients was observed using DSC analysis.

在处方前研究中，对盐酸尼卡地平的紫外吸收特性、不同介质中的溶解度和稳定性进行了测定，并利用DSC法考察了该药物与九种辅料（EC，HPMC，PVP，PEG6000，MCC，乳糖，淀粉，硬脂酸镁，SLS等）间的物理化学相容性。

The analysis of scanning electromicroscope showed that it didn't obviously exist protein granules in rice starch pured by alcalase, and the solubility and swelling power of rice starch increased respectively after purification.

扫描电镜分析大米淀粉的超微结构显示，碱性蛋白酶纯化处理后的大米淀粉中未见明显的蛋白质颗粒存在。比较纯化前后的大米淀粉发现，大米淀粉经过碱性蛋白酶纯化后，其溶解度和膨润力都明显增加。

The analysis results of scanning electromicroscope showed that protein granules didn't obviously exist in rice starch pured by alcalase, and the solubility and swelling power of rice starch increased remarkably after purification.

扫描电镜分析大米淀粉的超微结构显示，碱性蛋白酶纯化处理后的大米淀粉中未见明显的蛋白质颗粒存在。比较纯化前后的大米淀粉发现，大米淀粉经过碱性蛋白酶纯化后，其溶解度和膨润力都明显增加。

Compared with non-nanopolyaniline synthesized by conventional emulsion polymerization, nanopolyaniline has the narrow and uniform distribution of particle dimension and the diameter of particle is about 4-5nm,and the conductivity reaches 3.2S·cm-1, which is more than 100 times higher than that of nanopolyaniline;Moreover, it has higher solubility in conventional solvent and the solubility reaches 95% in N-methyl pyrrolidone;what's more ,it has higher crystallinity and more uniform crystal proved by XRD, apparent blue shift indicated by UV, which makes it possible to prepare transparent conductive composite films.

结果表明，微乳液法合成的纳米聚苯胺与常规乳液法合成的非纳米聚苯胺相比，具有明显的优越性：粒径分布窄，95%的在10nm 以下，最大的不超过30nm；电导率较高，达到了3.2S/cm，提高了2 个数量级以上；在有机溶剂中的溶解度较高，其中在N-甲基吡咯烷酮中的溶解率达到了95%；X 射线衍射仪分析表明，纳米聚苯胺结晶度高，晶型更为规整；紫外可见光谱研究发现，纳米聚苯胺在可见光区有明显的蓝移，为制备透明的导电复合膜提供了可能。

Results The purity and following treatment of inclusion bodies of CPB were influenced by the culturing temperature after the inducement with IPTG. The solubility of inclusion bodies of rCPB in 10mol/L urea was 2~3 times higher than in 8 mol/L urea, and the renature solution with 0.75%β-ME in 10mol/L urea could increase the solubility of inclusion bodies of rCPB, comparing with that in 10mol/L urea simply.

结果诱导后生长温度不同对rCPB包涵体的纯度及后期处理均有影响；rCPB包涵体在10 mol/L尿素溶液中的溶解度比在8 mol/L 尿素溶液中提高2~3倍；添加0.75%β-巯基乙醇能显著改善rCPB包涵体的溶解效果。

Autocorrelation topological study on the acute toxicities of substituted aromatic compound s;2. The autocorrelation topological researches on slow and acutetoxicities of substituted aromatic compound s to scenedesmus ubliquus, rat and so on;3. Results show that the SW and KOW of the substituted aromatic compound s could be better forecasted at AM1 level.

应用分子力学方法MM+和半经验量子化学AM1、MNDO和PM3法得到了54种取代芳烃的优势构象，在此基础上结合分子图形学技术，获得相应优化构象的电子结构参数和几何结构参数，并将这些参数与取代芳烃的辛醇/水分配系数和溶解度相关联。

On the basis of above works, dibutyl sebacate and 1、2-cyclohexanedicarboxylic acid diisobutyl ester were chosen to be absorbents of MA according to the solubility and property of solvents.

第二：在前一部分工作基础上，考虑了溶解度测定结果和溶剂本身性质选择有机溶剂癸二酸二丁酯和溶剂六氢化邻苯二甲酸二异丁酯作为吸收顺酐的吸收剂。

In order to recycle extra caustic soda and increase purity of sebacic acid, the research work in this thesis includes: extra caustic soda recovery, purification of sebacic acid and determination of solubility of sebacic acid in water, ethanol, and ethanol aqueous solution.

但是，它的传统生产工艺中存在过量游离碱浪费，癸二酸产品纯度不高等问题。对此本文做了三方面的研究，包括改进癸二酸生产工艺回收过剩的游离碱；提纯癸二酸；测定癸二酸在乙醇、水、乙醇水溶液中溶解度。

A set of apparatus for determining solid-liquid equilibrium data at atmospheric pressure has been established. The solubility of sebacic acid in water, 20% ethanol aqueous solution, 50% ethanol aqueous solution, 80% ethanol aqueous solution and ethanol were determined. Wilson equation, ideal thermodynamics equation and λh equation were applied to describe solid liquid equilibria data.

建立了一套常压固液平衡测定装置，测定了癸二酸在水、20％乙醇-水溶液、50％乙醇-水溶液、80％乙醇-水溶液、无水乙醇体系中的溶解度，并用Wilson方程、热力学简化方程和λh方程模型对实验数据进行关联。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。