溶血

Three fibrinolytic proteases, which were designated as BPGFP1, BPGFP2 and BPGFP3 individually, were purified from the gut extract of larvae of Boettcherisca peregrina fed on artificial diet containing fibrin rich pig blood coagulated block.

从以富含纤维蛋白的血凝块为食物的棕尾别麻蝇幼虫肠道浸提液中分离纯化出 3种具有溶纤活性的蛋白酶，分别命名为BPGFP1，BPGFP2和BPGFP3。

Danshensu and protocatechualdehyde, the water soluble ingredients of SM, were absorbed to blood in rats by oral, and 75% ethanol and ammonia extracts of SM, sodium danshensu and protocatechualdehyde, obviously increased OD in the experiment of amphotercin B cell model and the expression of CYP7AmRNA in BRL cell line.

丹参水溶性成分丹参素和原儿茶醛口服后均能吸收入血，丹参75％乙醇提取物和丹参氨水提取物及其部分单体，在两性霉素B细胞模型实验中均能明显增加OD值，同时亦能明显增加肝细胞CYP7AmRNA表达。

Methods Concanavalin A, wheat germ agglutinin, Sambucus nigrn agglutinin, Ricinus communis agglutinin-I and phytohemagglutinin were labeled with horseradish peroxidase by an improved sodium periodate method, and the synthetic HRP-agglutinins were used for determination of the expression levels of polysaccharide in common α-hemolyic streptococcus and in the α-hemolyic streptococcus after space mutagenesis.

采用改良的过碘酸钠法将辣根过氧化物酶分别标记在刀豆凝集素、麦胚凝集素、接骨木凝集素、蓖麻凝集素I及植物血凝素上，合成HRP-凝集素，检测普通型α-溶血性链球菌及太空型链球菌菌体内多糖分子的表达水平。

Concurrently, these molecular markers may contribute to screen , confirm and treat thrombotic diseases in clinic.

同时，这些凝血、纤溶及免疫系统的分子标志物也可能为血栓形成性疾病的临床诊断与治疗提供依据。

Endothelium-derived nitric oxide plays an important role in the regulation of vasomotion and the balance between thrombosis and thrombolysis.

血管内皮细胞产生的一氧化氮(nitric oxide，NO)在调节血管舒缩、维持凝血—溶栓平衡方面扮演着重要的角色。

Methods Veinous blood was sampled for determination of markers of the fibrinolytic system and hypercoagulability at admission and on the 10th day in patients with acute coronary syndrome, including acute myocardial infarction in 15 and unstable angina pectoris in 20. An occlusion test to determine the maximal endothelial tPA release was performed in order to evaluate the endothelial tPA reserve capacity. 20 patients with stable angina pectoris and 12 normal subjects served as control.

35例ACS患者，其中急性心肌梗死15例和不稳定心绞痛20例，于入院当日和入院后第10天采集静脉血样以测定纤溶、凝血指标，以评价内皮tPA储备功能；同时做静脉闭塞试验以确定最大内皮tPA释放，并与稳定性心绞痛和正常人作对比。

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活，ICAM-1表达升高，与被激活的PMN表面表达的LFA-1相结合，&PMN-EC&相互作用加剧，一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍；另一方面粘附的PMN过度吞噬或激活，当白细胞吞噬的颗粒不能被封闭隔离，连同细胞内的酶被释放出来，其中的PMN-elastase能够降解细胞基质中各种成分，水解多种蛋白，加重胰腺的毛细血管内皮细胞和腺泡的损伤；释放的溶酶体酶使组织蛋白水解，产生的不饱和脂肪酸引发脂质过氧化方应，破坏细胞膜的结构和功能；释放的炎性细胞因子，激发其他的免疫细胞的功能，导致进一步的组织损伤和坏死，加重SAP的病理损伤，最终导致休克、脓毒血症及多器官功能障碍等严重后果。

Methods 38 cases with 53 hips of ANFH treated with the method of thrombolysis and opening catheterizing and perfusing medial and lateral circumflex arteries.Those drugs are Urokinase 200 thousand Units,Danshen Root 20 ml and Ligustrazine 20 mg. Retention catheter was held in the target vessels and infused the same drugs besides Heparin 4500u in 3 days. To evaluate therapeutic effect ,the DSA of the femoral artery and x-ray plain film and/or CT/MRI of the femoral head were performanced. Results All cases were followed up 1~16 (mean 9.5) months.

方法对38例ANFH患者的53髋先常规行股动脉DSA，后在股骨头的供血动脉旋股内、外侧动脉内灌注溶栓、扩血管药物，即在每支血管内注入稀释后的尿激酶 20万u、丹参10 ml及川芎嗪20 mg；术后保留导管于动脉内，经导管每日注入同剂量的药物及肝素钠4500 u，连用3天后拔管，治疗后复行股动脉DSA检查及行股骨头X线平片及/或CT、MR随访以评估疗效。

The anti- tumor activeness of activity was mainly the function of dissolving activity and suppressing blood platelet polymerization, and has disturbed the blood textile fiber and tumor cell congealing.

菠萝蛋白酶的抗肿瘤活性主要被解释为其纤溶活性和抑制血小板聚合的作用，认为菠萝蛋白酶干扰了血纤维和肿瘤细胞的凝结。

Objective: To investigate the changes of blood coagulation and fibrinolysis in patients with acute craniocerebral injuries and to assess their relationship with patients' diagnoses and prognoses.

目的：探讨急性颅脑创伤患者伤后早期凝血和纤溶变化以及与病情危重度GCS及与预后的关系。

The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作：对伸臂位于顶部的单层框架—筒体模型进行分析，提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。