溶癌的

Mitochondria was relatively little in size. Round primary lysosome with high electron-densed granules and secondary lysosome with high or low electron-densed granules were seen frequently. DCs contained many rough endoplasmic reticulum, the Golgi apparatus and ribosomes. The vacuoles with flocculent electron-densed granules were rare. Some special granules in cytoplasm were seen, whose surface like earphone were covered with a membrane. High electron-densed contents in the granules were near one side and the other side was bright. The nucleus became markedly small in volume, nephroid or hoofed in shape. The nucleus had little euchromatin and lots of heterochromatin under nuclear membrane.

子宫内膜癌组织DC超微结构特征如下：细胞形态不规则，与正常子宫内膜组织DC相比，胞膜较光滑，胞膜表面树突状胞浆突起显著减少，部分突起呈粗短状；胞质中线粒体相对少，圆形而电子密度高的初级溶酶体和不规则形且电子密度高低不一的次级溶酶体多见；高尔基体、粗面内质网、核糖体丰富；含微量絮状电子致密物的胞饮小泡显著减少；胞质中可见形态特殊的颗粒，该颗粒外周膜包裹，略呈圆形，中间部位稍弯曲，如耳机状，颗粒中由高电子致密物居于一侧，而另一侧则呈透亮状；胞核显著减小，居于胞质一侧，常呈肾形或马蹄形，核内常染色质较少，异染色质多边集于核膜下。

Results:①The center of the homogeneous density soft tissue masses (mean CT value was 50HU) were located in the middle and lower tympanum,and the external auditory canal or the pharyngotympanic tube was involved in the earlier period;②the destructed b...

结果：中耳癌的CT特征：①表现为以中、下鼓室为中心的软组织密度灶，密度均匀，CT值50HU左右，外耳道及咽鼓管早期受累；②呈溶骨性骨质破坏，形态不规则，边缘无骨硬化表现，外耳道后壁破坏较前壁严重；③病灶侵入颞叶，形成肿块，灶周脑水肿不明显；④增强扫描见病灶有中度强化。结论：CT能确定中耳癌的存在及精确显示肿瘤累及范围。

Compared with control,①the mean tumor weight of H22 of SXKA Granules three dose groups were decreased significantly(P.01,P.05),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 30%;②the mean tumor weight of S180 of SXKA Granules three dose groups were decreased significantly(P.01),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 32%;③the mean tumor weight of EAC of SXKA Granules three dose groups were decreased significantly ( P.01, P.05),and the mean inhibition rates of SXKA Granules 20 g/kg dose groups were above 38%;④the mean tumor weight of Lewis carcinoma of SXKA Granules three dose groups were decreased significantly(P.01, P.05),and the mean inhibition rates of SXKA Granules 20、10、5 g/kg dose groups were above 36%;⑤the mean tumor weight of W256 of SXKA Granules three dose groups were decreased significantly ( P.01, P.05),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 32%;⑵Compared with control,SXKA Granules 20、10 g/kg dose groups had extended the survial time of the P388-bearing mice respectively(P.01),and the mean prolong rates of SXKA Granules 20、10 g/kg dose groups were above 50%;⑶Compared with S180-bearing group, SXKA Granules 20、10 g/kg dose groups could increase the weight of thymus and spleen, Spleen index and thymus index were increased, SXKA Granules 5 g/kg dose group could increase thymus index(P.05);⑷As Compared with control group, SXKA Granules 20、10 g/kg dose groups could improve mouse serum half hemolysis value depressed by transplanted tumor dramatically(P.01), which revealed the SXKA granules could improve the mouse humoral immunity system;⑸SXKA Granules 20 g/kg dose group could increase of englobe indexαon S180-bearing mice remarkably(P.01), which indicated the SXKA Granules could improve their cellular immunity system.

对荷W256大鼠，生兴克癌冲剂20、10、5 g / kg三组的平均瘤重明显低于对照组(P.01，P.05)，生兴克癌冲剂20、10 g / kg组的平均肿瘤抑制率均大于32 %；⑵与空白对照组相比，生兴克癌冲剂20、10 g/ kg能显著地延长移植小鼠白血病P388小鼠的存活天数(P.01)，生兴克癌冲剂20、10 g/ kg对荷白血病P388小鼠生命延长率均在50%以上；⑶与S180荷瘤组相比，生兴克癌冲剂对荷瘤鼠的免疫器官重量、胸腺指数和脾指数有一定的提高趋势，其中生兴克癌冲剂5 g / kg组对荷瘤小鼠的胸腺指数有一定的提高作用(P.05)；⑷与S180荷瘤组相比，生兴克癌冲剂20、10 g /kg组可提高由荷瘤引起的小鼠血清半数溶血素值的降低(P.01)，表明其可提高荷瘤小鼠体液免疫功能；⑸与对照组相比，生兴克癌冲剂20 g /kg组可提高荷S180肉瘤小鼠的免疫吞噬系数α值(P.01)，表明其可提高荷瘤小鼠细胞免疫功能。

Objective To investigate the effect of the treatment of surgery and bone cementing to heal osteolytic metastatic carcinoma of vertebra body and four limbs metaphysis.

目的 探讨应用外科手术联合骨水泥灌注治疗椎体和四肢干骺端部位溶骨性转移癌的治疗效果。

Breast cancer commonly metastasizes to bones, producing both osteolytic and osteoblastic deposits. Different markers for quantitative determination of bone turnover have been developed to evaluate bone metastases of breast cancer. The urinary deoxypyridionline, a crosslink product of collagen molecules found in bone and excreted in urine during bone degradation, and bone specific alkaline phosphatase, an isoenzyme localized in the membrane of osteoblasts and released in circulation during bone formation, were recently described as a group of markers of bone turnover in metastatic cancer.

乳癌患者常见骨髓转移造成溶骨性及成骨性沈积物，而利用不同标记来定量骨质转换形态，可以评估乳癌骨骼转移的变化，而尿液中Deoxypyridinoline是骨质内胶原分子在骨骼破坏分解时至尿中的产物，骨特殊碱性磷酸酵素是一种同形酵素，位於成骨细胞的外膜且在骨骼形成时释放至血液中，利用此两种生化标记，可以来预测乳癌转移至骨骼的转换情形。

Based on which, we will have the chance to advance the study of BTV"s targeting mechanism on molecular level, and realize the virion"s genetic modification for the safer application in human body in the future.

本研究为BTV所具有的特殊靶向性抗癌生物学特性充实了实验理论依据；亦为深入研究BTV靶向性抗癌分子机理和用基因工程技术发展更理想的重组dsRNA靶向性溶癌病毒，奠定了实验室技术基础。

This article reviews progresses of oncolytic virus in treating pancreatic carcinoma and possible mechanism.

现对溶瘤病毒治疗胰腺癌的作用机制进行综述。

Here we show that differential RNA export between normal and tumor cells is the major determinant of ONYX-015 oncolytic selectivity.

这里我们说明了正常细胞和肿瘤细胞RNA导出的差异是决定ONYX-015溶癌选择性的重要因素。

The advantage of using oncolytic virus to treat pancreatic carcinoma is that not all cell needed to be infected and the normal cells can not be affected.So,it has wide application future.

使用溶瘤病毒治疗胰腺癌的优点在于并不是每一个细胞都需要病毒转染，并且正常组织细胞不会受到影响，因而具有非常广阔的应用前景。

Shanghai Sunway Biotech Co. Ltd. announced today that the Chinese State Food and Drug Administration has approved H101, an oncolytic adenovirus, to be used in combination with chemotherapy as a treatment for patients with late stage refractory Nasopharyngeal cancer, a type of head and neck cancer prevalent in China.

上海Sunway生物技术有限公司今天宣布，H101已获中国国家食品药品监督管理局批准。H101是一种溶瘤腺病毒，与化疗相结合用于晚期难治愈的鼻咽癌――中国国内的一种常见头颈癌――的治疗。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。