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溴化乙烯

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Starting with two reactive methylene compounds, ethyl cyanoacetate and malononitrile, two 5-amino-1H-pyrazoles were prepared through the intermediates ketene dithioacetal.

从两个活泼亚甲基化合物开始,经过乙烯酮二硫代缩醛中间体,合成了两个5-氨基-1H-吡唑,以这个两个化合物为中间体,与芳香族和脂肪族α-溴代酮反应,而后经酸催化亚胺化互变异构后得到含咪唑并[1,2-b]吡唑甲硫醚类化合物6a-6g。

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