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The solution of sulfuric acid was added dropwise to the reaction vessel contained 1,3-dichloro-2-propanol, sodium dichromate and water.

将硫酸水溶液滴加到1,3-二氯-2-丙醇与重铬酸钠水溶液的混合物中,在温度23~27℃的条件下搅拌反应5 h,重铬酸钠∶1,3-二氯-2-丙醇=1∶2,此条件下收率为79.6%。

The SMMC-7721 hepatoma cell line of experimental groups and control groups were cultured with the addition of sodium selenite, potassium iodide or triiodothyronine (T3). The cell quantity was checked by the MTT assay , and the cell cycle was observed by flow cytometry and levels of AFP and ALB in the culture solution were determined by RIA.The SD rats were divided into positive control group, negative control group, T3 group and mixture group (the mixture of sodium selenite, KI and T3). After two weeks of the administration of sodium selenite、 KI and T3,Walker256 cells were transplanted into the abdominal cavity. The administration was kept on for another two weeks, then observed the morbility and mortality of the rats with ascites carcinoma. At the end, the ascites were for the cells counting and the cell cycles analysising.

方 法:在体外,应用细胞培养的方法,培养SMMC-7721肝癌细胞系,分为试验组和对照组,试验组加入不同浓度Se、I或T3干预,培养一段时间后,通过噻唑蓝试验、流式细胞仪,观察细胞数量及细胞周期的变化,测定细胞培养上清液中甲胎蛋白、白蛋白的水平,观察细胞分化情况;在体内,将试验用SD大鼠分成阴性对照组、阳性对照组、T3组和混合组(为Se、I和T3混合物),首先预防性用药2周,然后给试验组大鼠和阳性对照组大鼠腹腔注射Walker256细胞,制造腹水癌大鼠模型;继续用药2周,观察各组大鼠发病率及死亡率,测量不同时期大鼠血清FT3含量,通过流式细胞仪测量大鼠腹水细胞数及细胞周期变化。

The 1:1 mixtures of chaconine and solanine or solamargine and solasonine, produced markedly synergistic effects while the mixtures of unpaired glycoalkaloids from different plants did not have this effects.

卡茄碱与茄碱,澳洲茄边碱与澳洲茄碱的1:1的混合物产生了明显的协同作用,而来自于不同植物的不成对的糖苷生物碱则没有这种协同作用。

The compounds are represented by the structural Formula 1, Chemical formula should be inderted here as it appears on the abstract in paper form. a prodrug thereof, or any pharmaceutically acceptable salt, solvate, isomer or racemic mixture of the compound or said prodrug wherein R1 is heteroaryl, N-arylaminocarbonyl, N-heteroarylaminocarbonyl, benzimidazolyl or benzothiazolyl; R15 is present or not and if present is H, aryl, alkyl, arylalky or heteroarylalkyl; A is aryl, heteroaryl, cycloalkyl, cycloalkylidene, heterocycloalkylidene or heterocycloalkyl wherein said aryl, heteroaryl, cycloalkyl, cycloalkylidene, heterocycloalkylidene and heterocycloalkyl moieties may be substituted or unsubstituted; and B, L, X and R18 are defined herein.

所述化合物用结构式1表示,包括其前药或所述化合物或所述前药的任何药学上可接受的盐、溶剂合物、异构体或外消旋混合物,其中R 1 为杂芳基、N-芳基氨基羰基、N-杂芳基氨基羰基、苯并咪唑基或苯并噻唑基;R 15 存在或不存在,如果存在,则为H、芳基、烷基、芳基烷基或杂芳基烷基;A为芳基、杂芳基、环烷基、环烷叉基、杂环烷叉基或杂环烷基,其中所述芳基、杂芳基、环烷基、环烷叉基、杂环烷叉基和杂环烷基部分可被取代或未被取代;B、L、X和R 18 如说明书所定义。

The mixture was ignited at the blade tip by an automobile sparking plug.

被点燃的混合物在叶尖的汽车火花塞。

In the last part of the thesis, synthesis of mesostructured titania has been explored with a selfassembly of hydrophilic polymer and anionic surfactant used as template, along with titanium alkoxide as inorganic precusor. The product was proved to have mesostructure and the fiber and spherical morphology is favored.

本文最后一部分首次探索以亲水性高分子和阴离子表面活性剂形成的自组装体为模板、烷氧基钛为无机原料合成介相结构氧化钛;产物具有介相结构,其颗粒形貌为纤维和圆球的混合物

Hai Yu is straw of a bottle of corn, wheat straw, will straw, careless, the mixture such as wood chip falls into replete in the tank of white spherule ball and water, say to the reporter these are cellulose.

海玉将一瓶玉米秸、麦秸、稻草、草、木屑等混合物倒进一个装满了白色小球球和水的大容器中,对记者说这些是纤维素。

Spiced mixture of chopped raisins and apples and other ingredients with or without meat .

加香料的混合物,由切碎的葡萄干、苹果和其他成分组成,掺或不掺肉。

In case of spillage of NLS cargo on deck, in the water or incidental mixture with other

到该混合物可能会产生危险的反应。

Improper use may cause the mixture to splatter and cause burns.

不正当使用可能导致混合物飞溅,造成灼伤。

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In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

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