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淋巴结

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Methods After Candida albicans were inoculated into the specific pathogen free mice, the total amount of Candidas in cecum and the amount of which attached to the mucosal membrane were counted at different interent intervals. The lymphocyte proliferation in Peyer's patch and in lamina proper was shown by BrdU incorporation, meanwhile B cells isotype switch in PP was investigated. IgA plasma cells were shown by immunohistochemical staining. Specific IgA antibodies to Candida albicans were measured with ELISA.

采用无特殊病原菌动物经口喂入白念菌,在不同时相处死后,观察肠内白念菌总数及肠粘膜表面白念菌粘附数量;取肠系膜淋巴结做白念菌选择培养,观察移位体内发生率;采用Brdu体内掺入显示局部粘膜淋巴细胞的增殖情况;流式细胞计数潘伊尔氏结细胞表面IgA阳性率;免疫组化染色后计数固有层中IgA浆细胞数量变化;ELISA法测定肠粘液中特异抗白念菌IgA含量。

The infection of HPV type 16, 18 DNA was determined by PCR. Results There were significant differences for survivin and CD44v6 between carcinomas, CIN and normal cervices (P.01, respectively).

结果 survivin和CD44v6的阳性率在宫颈癌组织中远高于CIN和正常宫颈组织,差异显著(均P.01),其表达率与淋巴结转移有关

The results suggested that enzyme activity may be Immunological marker in lympho cytes of the lymph nodes around cancer of experimental liver carcinogenesis.

结果提示:实验性肝癌周淋巴结淋巴细胞酶活性变化可作为研究肝癌免疫功能的客观指标。

Draining lymph nodes isolated from the BALB/C mice immunized with rabbit skin collagen Type Ⅲ accord- ing to a rapid immunization protocol, the lympho- cytes were fused with the myeloma cell line NS-1, 3 out of total of 201 growing hybridomas we obtained were producing collagen Type Ⅲ reactive antibodies after 3 limited dilution clones performed.

本实验采用快速免疫的方法用兔皮肤Ⅲ型胶原免疫BLAB/C小鼠,取淋巴结的细胞与小鼠骨髓瘤细胞NS-1融合,240孔中201孔有杂交瘤生长,用ELISA检测有6孔反应阳性。选3孔生长良好,抗体浓度高的细胞进行有效的有限稀释法克隆3次,获3株分泌抗Ⅲ型胶原单克隆抗体的杂交瘤细胞。其中二株属IgG2b,一株为IgG1。

Bases on these findings, the patient was diagnosed as having primary cutaneous eccrine adenocarcinoma with metastases to the adjacent skin and lymph nodes.

根据这些发现,该病人被诊断为原发的皮肤小汗腺癌并伴有相临皮肤和淋巴结转移

Of all these patients, the eyelid in 10 cases, parotid in 2cases, external auditory meatus in 5 cases, maxillofacial in 7 cases, neck portion in 4 cases, neck lymph node metastasis in 3 cases. They were treated with surgical operation, radical therapy and chemistry therapy.

结果 皮脂腺癌确诊需要免疫组化检测,而罕见的腮腺皮脂腺癌还需和透明细胞癌、黏液表皮样癌和腺泡细胞癌鉴别,全组病例5年以上随访,5年生存率可达71.4%(20/28),5年内原发灶复发10例,其中,3例伴有区域淋巴结转移而再次手术,4例失访;2例死于远处转移;2例死于其他疾病。

There was no difference between breast cancer and fibro adenoma tissues in ERαexpression.The expression of ERαin breast cancer tissues was not associated with histological types,age,clinical stage,lymph node metastases state,HER-2 and P53 protein expression.

结论1、乳腺癌组织ERα蛋白表达与乳腺纤维腺瘤组织比较无显著差异;乳腺癌组织中ERα蛋白表达与患者年龄、病理类型、临床分期、淋巴结转移、P53、HER-2蛋白无关,与PR蛋白表达正相关。

Multivariate analysis considering caveolin-1 immunoreactivity in addition to the established prognostic parameters such as pT stage, pN in these patients confirmed that caveolin-1 is an independent functional predictor of poor survival. We further revealed that up-regulated caveolin-1 in CL cells is necessary for mediating filopodia formation which may enhance the invasive ability of lung adenocarcinoma cells.

利用多变数分析的方法分析Caveolin-1及其他已知会影响预后的变数,例如肿瘤大小及淋巴结转移状况等,证实Caveolin-1的确是影响预后的独立变数,最后我们发现Caveolin-1会引起肺腺癌细胞产生伪足,这可能是Caveolin-1造成癌细胞侵袭性增加的原因。

The results showed that the sheep had fibrinous pneumonia and lymphocyte interstitial pneumonia, which were typical pathologic changes of this disease. Remarkable changes were observed in the lung: fibrinous exudates, infiltration of inflammatory cells, pleura thickening, interstitial edema, hemorrhage and formation of thrombiand lymph clot. The heart, liver and kidney had different degeneration degree. Reactive hyperplasia presented in bronchales lymphonodi.

结果发现该病例具有胸膜肺炎的典型病理变化,呈现纤维素性肺炎和淋巴细胞性间质肺炎,纤维素性物质的渗出和炎性细胞的浸润很明显,肺胸膜增厚,同时在肺间质还可见水肿、出血、血栓和淋巴栓的形成;另外心、肝、肾也均有不同程度的变性,淋巴结呈反应性增生。

Results All their expressions were correlated with tumor metastasis;there is an inversing association between nm23 and PCNA、SPF.

结果 nm23、PCNA、S期细胞比均与胃腺癌淋巴结转移有关;nm23表达与PCNA分级、S期细胞比呈负相关。

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