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And the effect of the synthesized compounds to T-lymphocyte transformation was investigated using methyl thiazolyl tetrazolium method.

结果显示:长链酰基取代后的化合物4a~4d和5a~5d对小鼠T-淋巴细胞增殖的抑制活性明显优于未取代的底物2和3。

Background: The widespread use of prophylactic ganciclovir and anti-lymphocyte/thymocyte therapies are associated with increased induction of ganciclovir-resistant cytomegalovirus strains.

背景:预防性更昔洛韦以及抗淋巴细胞/胸腺细胞疗法的广泛使用导致了耐更昔洛韦的巨细胞病毒的诱导。

In this study,triploid Caspian salmon have a similar WBC count in comparison with diploids,but triploidy affected lymphocyte portions of WBC.

在这项研究中,三倍体里海鲑鱼与二倍体有一个类似的白细胞计数,但三倍体影响了的白细胞的淋巴细胞部分。

In conclusion, our study demonstrated that ALA-PDT could selectively deplete allogenic T lymphocytes in allograft.

根据以上的结果,得到如下的结论:(1)ALA-PDT能够选择性清除小鼠同种异体激活的淋巴细胞。

Addition of exogenous IL-2 to the tolerant BALB/c→B6 MLR cultures system, only partially restored the proliferative responses, indicating that anergic T cells clones may induce tolerance to the allograft.

在耐受BALB/c→B6小鼠的单向混合淋巴细胞反应体系中加入外源IL-2可以部分反转耐受BALB/c小鼠脾细胞的增殖反应,表明本实验诱导耐受的机制可能与克隆不应答有关。

MethodsThe immunosuppressive mouse model was established by using hydrocortisone. Huangqi Fuzhengtang and Yupingfeng San apozema were given to the mice intragastrically. The contents of hemolysin, IL-2, and INF-γ in the mouse serum and the expression of CD3+, CD4+, and CD8+ in the peripheral blood lymphocytes were measured.

以氢化可的松造成免疫低下小鼠模型,用黄芪扶正汤和玉屏风散水煮液进行灌胃,检测小鼠血清溶血素的生成、IL-2和INF-γ的含量以及外周血淋巴细胞CD3+,CD4+和CD8+的表达。

The results showed that the values of CD4, CD4/CD8 were all lowered in these cases, sIL - I R increase which was even more conspicuous in deficient group, indicating that there were cytological immuno - defect and disharmoney of immunological balance. Therefore, both the T - lymphocyte subgroup and sIL-Ⅱ R can be served as indices for differentiation of sthenic and asthenic syndrome types.

结果表明,慢性肝炎患者CD_4及CD_4/CD_8值下降,CD_8及sIL—2R值上升,且虚证组较实证组更为明显,说明慢性肝炎患者存在细胞免疫功能的缺陷及免疫平衡的失调,T淋巴细胞亚群及sIL—2R可作为慢性肝炎中医虚实辨证的客观化指标之一。

Methods By establishing the apoptosis model of primary culture of hippocampal neurons induced by hyperthermia, the dynamic change of concentration Ca(superscript 2+)in hippocampal neurons and the influence to Bcl-2 expression were observed after using chelerythrine chloride which was the special inhibitor of PKC.

通过建立体外高温诱导海马神经细胞原代培养的凋亡模型,应用PKC特异性抑制剂氯化百屈菜红碱,观察海马神经元胞内Ca(上标 2+)浓度的动态变化以及对B淋巴细胞瘤基因2蛋白(Bcl-2)表达的影响。

Objective To study the effect of monocyte chemotactic protein-1(MCP-1) on the proliferaion of tumor infiltrating lymphocytes in patients with transitional cell cancer of bladder and their cytoxicity to bladder tumor.

目的 探讨不同浓度的单核细胞趋化因子(MCP 1)对肿瘤浸润淋巴细胞增殖的作用,以及能否增加TIL对膀胱肿瘤细胞的细胞毒性。

Methods The Cynomorium polysaccharide and Cynomorium water extract were extracted and prepared chewable tablets. Wistar rats were randomly divided into normal control, aging model, VitE, Cynomorium polysaccharide chewable tablets and Cynomorium water extract chewable tablets groups. Dgalactose was injected to establish the aging model. After drug intervention, the proliferation activity of rat spleen lymphocytes stimulated by ConA was detected by MTT assay and the spleen index was measured. The pathological morphological changes of spleen were observed. The activity of superoxide dismutase, the content of malondialdehyde and nitric oxide in serum of rats were detected.

提取并制备锁阳多糖、水提取物咀嚼片;Wistar大鼠随机分为空白对照组、衰老模型组、维生素E对照组、锁阳多糖组、水提物组,以D半乳糖建立衰老大鼠模型,药物干预后,MTT法检测各组大鼠脾淋巴细胞对ConA刺激的增殖能力,检测各组大鼠脾脏指数,观察脾组织的病理形态学变化;并检测各组大鼠血清中超氧化物歧化酶活性、丙二醛及一氧化氮的含量。

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