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The level of intense of proliferation of fetal lymphocyte was significantlyincreased in ICP group than those of normal control group in dermic soluble antigen induced lymphocyte proliferation reaction.

采用单向混合淋巴细胞反应法对照研究20例ICP患者及正常孕妇的胎儿淋巴细胞对母体外周血的单个核细胞,皮肤组织可溶性抗原,蜕膜组织可溶性抗原的增殖情况。

TFC could remarkably inhibit the ear edema induced by dimethylbenzene in mice at the dose of 125,250,500mg.kg~(-1), the swelling of rats hind paws induced by carrageenan and primary inflammatory reaction in AA rats at the dose of 84,168,336 mg.kg~(-1) and reduce the weight of granuloma induced by cotton in rats at the dose of 84,168,336mg.kg~(-1), respectively.

TFC的免疫调节作用体外研究发现,TFC0.005,0.05,0.5,5,50 mg·L~(-1可明显提高环磷酰胺(cyclophosphamid,Cy)诱导免疫功能低下小鼠的脾淋巴细胞增殖反应,而对正常小鼠的脾淋巴细胞增殖无明显作用。

The re-suits showed that IL level in serum of Ⅰ group goats decreased, whereas that of Ⅱ group goats increased, TNF-α levels in serum and IL-2 in supernatant with proliferation of PBL of goats increased after infection. PBL of goats was responsible for antigen 1 week after infection. Immune response of PBL of goats infected with Fasciola hepatica on the special and non-special antigen obviously increased. The results suggested that TNF-α would participate in the course of liver damage caused by Fasciola hepatica.

结果表明,山羊试验感染肝片吸虫后,Ⅰ组山羊血清IL-2水平在感染后有所下降,而Ⅱ组山羊血清IL-2水平在感染后有所升高;感染不同剂量肝片吸虫的山羊血清TNF-α水平和淋巴细胞IL-2分泌水平均有不同程度的升高,在感染后第1周淋巴细胞就有反应,并且对非特异性刺激原和特异性刺激原的应答都有显著升高。

Immunorelated pancytopenia or hemocytopenia is a kind of disease with a relative clear pathological mechanism which was separated from bone marrow failure disease.It was thought to be caused by unbalance of T lymphocyte regulation and abnormal of B lymphocyte mount,subgroup,and function,which result in production of autoantibodies destroying or suppressing the inmature bone marrow hematopoietic cell and peripheral hypocytosis.

免疫相关性全血细胞减少或血细胞减少症是从骨髓衰竭性疾病中分离出的一种病理机制相对清晰的独立疾病体系,是由于T淋巴细胞调控失衡导致B淋巴细胞数量、亚群、功能异常,进而产生抗骨髓未成熟造血细胞自身抗体并破坏或抑制之,最终导致外周血细胞减少的一类疾病。

Objective: To investigate the situation of TCR Vβ gene repertoire and clonal expansion in peripheral blood T cells from patients with acute lymphoblastic leukemia and T cell strains, and analysis the expressive characters of TCR V β gene idiotype. To develop the anti-lymphoblastic leukemia TCR idiotypic DNA vaccine.

目的:了解淋巴细胞白血病及T细胞株的TCRVβ基因谱系及其克隆性增殖情况,分析TCR Vβ基因独特型表达的特点,并构建具有抗淋巴细胞白血病作用的TCR独特型DNA疫苗。

Be good at the lienal cure that change Yu can administer small environment of patient of cancer of the liver, correct the unusual expression of cellular factor and transcribe factor, change T lymphocyte inferior group unbalance condition, raise T lymphocyte active, enhance the T cell identifying to tumor cell function, immunity of changeover liver cancer escapes.

健脾化瘀治疗可治理肝癌患者微环境,纠正细胞因子和转录因子的异常表达,改变T淋巴细胞亚群的失衡状态,提高T淋巴细胞活性,增强T细胞对肿瘤细胞的识别功能,逆转肝癌免疫逃逸。

The second is the lymphocyte-forming organ and is a part of the immune system. It is the site where lymphocytic leukemia begins.

其次是一个淋巴细胞生成的器官组成了免疫系统的一部分,是淋巴细胞性白血病的发生部位。

Level of IFNγ secreted by splenocytes of immunized mice up-on antigen-specific stimulation was detected by using a cyto-pathic effect reduction assay and splenocytes proliferation of immunized mice in response to antigen restimulation was measured by MTT method.

分离免疫小鼠的脾淋巴细胞,体外用抗原再刺激,生物学方法检测IFNγ产生水平和MTT法检测淋巴细胞增殖。结果 RT-PCR检测证实pTB30m可在CHO细胞中表达。pTB30m免疫小鼠可引起较高水平的Ag85B特异性的抗体应答。

Allogeneic and syngeneic fresh bone, autolyzed antigen-extracted bone, bone matrix gelatin, demineralized bone matrix were implanted into the muscle pouch of mice, at different times after implantation, the immunological, histological and alkaline phosphatase assay were conducted. The results revealed that all four kinds of allogeneic implants activated specific cellular and humoral immune responses, most notably in fresh bone group, the AAA, BMG and DBM inhibited the proliferation of the lymphocytes in vitro and BMG had the most powerful inhibiting action, allogeneic AAA, BMG and DBM might induce heterotopic osteogenesis in vivo, however, there were obvious difference in ALP and histomorphometry between allografts and isografts.

在小鼠肌肉内植入同种异体或同系新鲜骨、自消化抗原去除骨、骨基质明胶、脱钙骨基质,术后免疫学、碱性磷酸酶、组织学检查发现:4种同种异体植入物均可引发特异性细胞免疫反应和体液免疫反应,其中以新鲜骨移植引发的免疫反应最为显著;自消化抗原去除骨、骨基质明胶、脱钙骨基质在体外具有抑制淋巴细胞增殖的作用,骨基质明胶对淋巴细胞增殖的抑制作用最显著;同种异体与同系4种植入物在体内成骨活性有显著差异;自消化抗原去除骨、骨基质明胶、脱钙骨基质均有异位诱导成骨活性,其中骨基质明胶骨诱导活性最佳。

However, there is growing evidence that B lymphocytes play a role in many T-lymphocyte–mediated diseases.

然而,越来越多的证据表明B淋巴细胞在T淋巴细胞参与调节的疾病中起一定的作用。

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如果你任何时候在跑步过程中气喘如牛,降低速度并且确保你能够深呼吸。