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淋巴细胞瘤

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Most aneurysms specimens showed structure changes, including injury of endothelial cell, disrupture or disappearance of the internal elasticlayer, scarce of contractile fiber cells.

动脉瘤瘤壁中有不同程度的单个核细胞成分的浸润(淋巴细胞或单核/巨噬细胞样细胞),尤其在"中膜"层或"中膜"与内膜交界处较为明显,同时,在细胞集中区伴有数量不等的新生的营养血管,以上改变类似"肉芽组织"样改变。

Methods 548 cases of nodular goiter, 35 cases of thyroid adenoma and 17 cases of thyroid carcinoma were collected.

收集 5 4 8例结节性甲状腺肿,35例甲状腺腺瘤,17例甲状腺癌,观察其伴淋巴细胞性甲状腺炎的发生率及病变特点。

They had higher SCE rate and micro nuclei rate, with 14.12times per cell, and 13.28 times per cell, respectively for SCE rate and 25.2% and 21.2%, respectively for micro nuclei rate, After treated wito mitomytin, they had even higher SCE (38.3、37.2)and micro-nuclei rate(10.7%,10.2%) than normal β-lymphoblast cell line.

现常用细胞EB病毒体外感染外周血淋巴细胞建立淋巴母细胞株,具永生性和不致瘤性,保持原有细胞的生物学特性,为实验室研究提供可信的材料[2]。

RESULTS:After pinealectomized mice was irradiated WBI with 75 mGy X-rays,we found levels of plasma corticosterone increased obviously,and the effects of the proliferative reaction of splenocytes to ConA and spontaneous proliferation of thymocytes was found to be decrease. But injecting melatonin into pinealectomized mice or putting melatonin in the cultured cell,its immune functions might renew the enhancement.CONCLUSION:Melatonin of pineal gland might regulate the immunoenhancement induced by low dose radiation.MeSH Pineal body; Melatonin; Radiation; Corticosterone; Immunity,cellular

低剂量辐射(low dose radiation,LDR)全身照射(whole body irradiation,WBI)可引起免疫系统的兴奋效应,主要表现在以T淋巴细胞功能激活为主的细胞免疫和体液免疫功能的增强并可提高机体的抗瘤作用[4,5],在LDR诱发免疫功能增强的同时伴有下丘脑-垂体-肾上腺皮质系统功能下调等神经内分泌功能的改变,神经内分泌对免疫系统的调节可能是LDR免疫兴奋效应发生的必要条件,松果腺MLT与辐射免疫兴奋效应的关系值得研究。

Effect of low-energy He-Ne laser irradiation on the proliferation reaction of splenetic T lymphocyte of S180-bearing mouse .

低能量氦氖激光照射对荷瘤小鼠T淋巴细胞增殖反应的影响。

MethodsThe tumor xenografts model was established by injecting the mouse lymphocytic leukemia cells (P388) in the subcutis of anterior axillary of Kunming mice, and then was treated with CZBG by intragastric administration and different doses of adriamycin by intraperitoneal injection.

方法将小鼠淋巴细胞白血病细胞系P388细胞接种于昆明小鼠腋前皮下构建小鼠移植瘤模型,予复方浙贝颗粒联合不同剂量的阿霉素治疗。

Selection criteria: Hypothyroidism with the increased thyroid microsomal antibodies, thyroid peroxides antibody, or thyroglobalin antibody which detected in city, and provincial hospital in gestation or before pregnancy were diagnosis as Hashimotos thyroiditis. Hyperthyroidism supported with the thyroid ultrasonography or ECT scans or confirmed by fine-needle-aspirate biopsy of the thyroid, excluded the hyperfunctioning thyroid adenoma and multinodular goiter, were diagnosis as Graves disease.

纳入标准:对妊娠前或妊娠期间曾在省、市级医院检查有甲状腺功能减退且伴有抗微粒体抗体或抗甲状腺过氧化物酶抗体、抗甲状腺球蛋白抗体增高者为慢性淋巴细胞性甲状腺炎孕母;有甲状腺功能亢进且甲状腺B超或甲状腺ECT扫描或甲状腺细针穿刺病理检查证实、并排除高功能腺瘤及多发性结节者为GraveS病孕母。

We describe a case of NLPHL showing a variant histologic pattern characterized by small and large clusters of lymphocyte predominance cells within nodules defined by follicular dendritic cell meshworks, associated with numerous neutrophils and areas of internodular fibrosis. Focally, the neoplastic cells had lacunar cell-like cytologic features.

在此,我们描述一例组织形态特殊的NLPHL,其形态学表现为以淋巴细胞为主的细胞排列成大小不等的结节,结节均由滤泡树突状细胞网网罗,结节内见中性粒细胞浸润,部分结节间见纤维化,局灶瘤细胞呈陷窝样。

This experiment also show KXP can enhance proliferative ability of the T, B lymphocyte, markedly reinforce the activity of natural killer cell and the phagocytic activity of celiac macrophagocyte, which prove KXPs importance in the antineoplastic immunity.

实验还表明:凯息平口服液能增强荷瘤鼠的T、B淋巴细胞增殖能力;对自然杀伤细胞的活性也有明显的促进作用,同时明显增强腹腔巨噬细胞的吞噬活性,显示了其在抗肿瘤免疫中具有重要的作用。

Methods:The syngenic mice were immunized with parental B16 tumor cells and B16.B fusing cells.Then,SPLs of immunized mice were co-cultured in vitro with parental B16 cells,the proliferation of SPLs and the secretion of certain cytokines were assayed.

分别取亲本B16黑色素瘤和融合瘤细胞B16.B主动免疫同系小鼠,观察免疫小鼠脾脏淋巴细胞对亲本瘤细胞体外再刺激的反应能力。

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