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淋巴细胞性白血病

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Results In those patients with marrow invasion , 4 cases in I phase(4.2%),12 cases in II phase(12.6%),36 cases in Ⅲ phase(37.9%)and 43 cases in Ⅳ phase(47.4%);small lymphocytic、diffuse cleaved cell、lymphoblastic lymphoma are main pathologic types;patients with mediastinal lymphadenectasis、splenomegaly and spleen violations are prone to catch bone marrow involvement;56 cases of anemia in patients with bone marrow involuement(58.9%)恶性淋巴瘤症状, 42 patients with thrombocytopenia (44.2%),27 cases with leukopenia (28.4%),49 cases of patients leukocyte increased (51.6%),so,anemia is common;three were 30 cases with three items abnormal(31.6%)and 65 cases with one item abnormal at least (68.4%),the incidence of abnormal peripheral blood in leukocythemia patients were higher than that in patients with bone marrow infiltration,Particularly the patients with increased leukocyte or three items abnormalities were more common in leukemia; Abnormal cells in peripheral blood were observed in 66 cases (69.5%); chemotherapy efficiency reached 65.2% in the patients with bone marrow involuement,the median survival time was 11.5 months.

结果发生骨髓侵犯病例中I期4例(4.2%), II期12例(12.6%),Ⅲ期36例(37.9%)恶性淋巴瘤分期,Ⅳ期43例(47.4%);病理类型以小淋巴细胞性,弥漫型裂细胞性(改为:弥漫性大B细胞型淋巴瘤)和淋巴母细胞性淋巴瘤多见;纵隔淋巴结肿大、脾脏肿大和脾受侵患者易发生骨髓侵犯;骨髓侵犯患者外周血中贫血56例(58.9%),血小板减少42例(44.2%),白细胞减少27例(28.4%),白细胞增高49例(51.6%),以贫血多见;三项均异常30例(31.6%),至少一项不正常65例(68.4%),淋巴瘤细胞白血病患者外周血象异常发生率高于骨髓浸润患者,尤其是白细胞增高或三项均异常者更常见于白血病;66例(69.5%)外周血分类中发现异常细胞;骨髓侵犯化疗有效率65.2%,中位生存期11.5个月。

People with CLL or CML may not have any symptoms.

慢性淋巴细胞白血病和慢性粒细胞性白血病的人可能没有任何症状。

Phylogenetic analysis of the long terminal repeatand env gene of htlv-1 gave a phylogenetic classification of htlv-1 genotypes into five major molecular subtypes: cosmopolitan, japanese, west african, central african, and melanesian. in order to understand the major genotype of htlv-1 prevalent in china, htlv-1 env gene was amplified by pcr and sequenced from peripheral blood lymphocyts of three htlv-1 carriers in the putian region of fujian province.

根据基因组及血清学反应可将其分为人t淋巴细胞白血病病毒1型(htlv-1)和2型(htlv-2),两型病毒基因组同源性大于60%。htlv-1主要侵染t淋巴细胞,可引起成人t细胞白血病、热带下肢痉挛性瘫痪或htlv-1相关脊髓病,并且在多种自身免疫病患者体内也发现了该病毒的存在。

A series of examination,including routine blood and bone marrow picture analysis,chest roentgenography,cranial computerized tomography and detection of cell genetics etc were carried out for a Ph+ALL patient combined with invasive aspergillosis.

为了探讨Ph染色体阳性急性淋巴细胞白血病合并侵袭性曲霉菌病的临床特点和治疗措施,对1例Ph+ALL患者进行了血常规、骨髓像、胸片、头颅CT扫描和细胞遗传学等检查,并先后给予DVCP、善唯达及格列卫联合诱导化疗。

Results The positive rate of binucleated granulocytes was 0%in normal contrast group. It was 53.0%in acute myeloid leukemia, 46.2%in chronic myeloid leukemia, 41.7%in reactive granulocytosis, and 38.4%in myelodysplastic syndrome. they were significantly higher than 8.2%in common anemia, 12.5%in idiopathic thrombocytopenic purpura, and 0%in lymphocytic leukemia.

结果 双核粒细胞阳性率,27例正常对照组为0,急性髓细胞白血病53.0%(80/151)、慢性髓细胞白血病46.2%(18/39)、反应性粒细胞增多症41.7%(20/48)、骨髓增生异常综合征38.4%(33/86),明显高于一般贫血8.2%(8/98)、特发性血小板减少症12.5%(4/32)和急性淋巴细胞白血病为0。

Objective: To investigate the situation of TCR Vβ gene repertoire and clonal expansion in peripheral blood T cells from patients with acute lymphoblastic leukemia and T cell strains, and analysis the expressive characters of TCR V β gene idiotype. To develop the anti-lymphoblastic leukemia TCR idiotypic DNA vaccine.

目的:了解淋巴细胞白血病及T细胞株的TCRVβ基因谱系及其克隆性增殖情况,分析TCR Vβ基因独特型表达的特点,并构建具有抗淋巴细胞白血病作用的TCR独特型DNA疫苗。

Cirrhosis of 93 liver after hepatitis is ill as a result WBC of exceptional week blood, Hb, RBC, PLT and contrast normally different of group appearance ratio has significance sense (P.05); marrow cytology checks main show to be anaemia of the lienal excessive, sex that be short of iron, aplastic anemia, chronic lymphocyte.

结果93例肝炎后肝硬化病例外周血WBC、Hb、RBC、PLT和正常对照组相比差异有显著性意义(P.05);骨髓细胞学检查主要表现为脾亢、缺铁性贫血、再生障碍性贫血、慢性淋巴细胞白血病、骨髓增生异常综合症等5种类型。

Objective To explore factors for differentiating non-Hodgkins lymphoma cell leukemia and acute lymphoblastic leukemia.

目的 对非霍奇金淋巴瘤细胞性白血病与急性淋巴细胞白血病进行鉴别诊断。

Such lymphocytes are indicative of acute lymphocytic leukemia.

这样的淋巴细胞提示急性淋巴母细胞性白血病的存在。

Methods The expression of CD87 was detected with flow cytometry in 54 AML patients and 20 acute lymphoblastic leukemia patients. The expressionsa of CD87 on U 937, HL-60 and K562 cells were also studied with FCM and reverse transcription-polymerase chain reaction during differentiation induced by phorbol myristate acetate in vitro.

应用流式细胞术检测了54例急性髓性白血病及20例急性淋巴细胞白血病患儿CD87的表达,还用FCM及逆转录-聚合酶链反应法检测了U937、HL-60、K562细胞在氟波酯作用下诱导分化过程中CD87表达的改变。

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