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淋巴细胞

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Activation of lymphocytes and liver regeneration both involve perinuclear clustering of lysosmes.

淋巴细胞的激活以及肝脏的再生都与溶酶体在核周的集聚有关。

Results The ACP reaction products were seen in the perinuclear region of the spreading blood cells, but they were not seen in the round blood cells.

结果 在钉螺血淋巴细胞中的伸展性阿米巴细胞胞浆中可见呈棕色颗粒的ACP阳性反应物,而圆形阿米巴细胞胞浆中未见呈棕色颗粒的ACP阳性反应物。

The liver specimens were immunohistostained by SP method (1)Fas antigen and FasLs specific positive signals were found mainly on the surface or/ and in the cytoplasm of the hepatocytes, these positive hepatocytes were scattered nearby periportal region and hepatic lobule with piecemeal necrosis, the infiltrating lymphocytes were mainly FasL-positive cells.

1Fas、FasL在肝组织肝细胞膜及胞浆均有不同程度表达,其表达阳性细胞主要位于汇管区小叶内及周边碎屑状坏死区,呈弥漫分布,在其周围浸润的淋巴细胞上多为FasL阳性细胞,亦可见到Fas阳性细胞。

METHODS: the supernatants of cultured spleen's lymphocytes induced by ConA were injected into mice peritoneally,kinetics of plasma corticotropin releasing hormone,adrenocorticotropic hormone and corticosterone in mice were tested at different time (0.5,1,2,4,6 h),or tissue of hypothalamus pituitarium or adrenal was stimulated with supernatants induced by ConA,and the secretion of CRH, ACTH and CORT were observed.

采用ConA诱导淋巴细胞培养上清液给小鼠腹腔注射,测定不同时间(0.5,1,2,4,6 h)的小鼠血浆中CRH,ACTH,皮质酮产生的动力学,同时在体外用ConA诱导上清液分别与下丘脑,垂体,肾上腺组织共同培养后观察CRH,ACTH,CORT分泌情况。

Dermal papilla layer of capillary proliferation and expansion of perivascular infiltration of lymphocytes dominated.

真皮乳头层内毛细血管增生和扩张,血管周围有以淋巴细胞为主的细胞浸润

The perivascular inflammatory infiltrates are mainly small lymphocytes without associated necrosis or other features of usual CNS lymphomas.

血管周围炎症细胞浸润主要是小淋巴细胞而未见坏死或者其他中枢神经性炎症时常见的其他征象。

The vein grafts with perivenous support by fibrin glue demonstrated a statistically decrease in neointimal and medial hyperplasia compared with non-supported vein grafts(p.01). immunohistochemical analysis showed that the expression of proliferating cell nuclear antigen was inhibited significantly in fs group compared with ns group. almost intact endothelium was showed in fs grafts(p.01). but in ns grafts there were severe endothelium damages where lymphocytes infiltrated. in ns grafts, the smooth muscle cells were hyperplasia and migrated to intimal, whereas in fs group, the hyperplasia of smooth muscle cells were inhibited and migrated to adventitia.

免疫组化结果显示与ns组相比,fs组移植静脉细胞增殖核抗原表达明显受到抑制;ns组内皮层损伤严重,有淋巴细胞侵润,而fs组内皮层则几乎完好无损(p.01);在ns组平滑肌细胞增殖活跃且向内膜迁移,fs组平滑肌细胞增殖受到抑制,且向外膜迁移;在fs组移植静脉外膜有丰富的成熟微小血管网形成,但是在ns组,微小血管数量则非常少。

Result The cultured DC from mouse bone marrow displayed the typical morphological characteristics of DC. Immature DC, which had high expression in CD11c and low expression in MHCⅡ and CD86, could phagocytize antigen. Mature DC, which had high expression in CD11c, MHCⅡ and CD86, could stimulate allogenic mixed lymphocyte proliferation.

未成熟DC的细胞表型为CD11c、MHCⅡ、CD86,具有极强的抗原吞噬能力;未成熟DC经LPS刺激培养后可转变为成熟DC,细胞表型为CD11c、MHCⅡ、CD86,可显著刺激同种异体混合淋巴细胞增殖。

Methods: Eighty mice were randomly divided into high, middle, and low dosage groups which were orally given 1.5 g/kg, 0.75 g/kg, 0. 375 g/kg of ant powder respectively, twice a day for 10 days. A blank control group was set up which was given water instead. Body weight, thymus weight and spleen weight were measured. Thymus indexes and spleen index were calculated. Neutrophil phagocytose rate, Ea and Et rosette formation rate of T lymphocytes, and hemolysin titre were detected. QHS values were achieved with spleen cell mediated sheep red cell spectrophotometer quantitative assay.

根据黑蚂蚁的用药量将小鼠分成高、中、低剂量及空白对照组,黑蚂蚁粉给药量按小鼠体重1.5g/kg、0.75g/kg、0.375g/kg计算,连续10d灌胃给药后,测定各组小鼠的体重、胸腺和脾脏重量,计算胸脾指数;检测中性粒细胞的吞噬率、T淋巴细胞E花环形成率及小鼠的溶血素效价和脾细胞介导的羊红细胞分光光度计定量测定法。

A blank control group was set up which was given water instead. Body weight, thymus weight and spleen weight were measured. Thymus indexes and spleen index were calculated. Neutrophil phagocytose rate, Ea and Et rosette formation rate of T lymphocytes, and hemolysin titre were detected. QHS values were achieved with spleen cell mediated sheep red cell spectrophotometer quantitative assay.

根据黑蚂蚁的用药量将小鼠分成高、中、低剂量及空白对照组,黑蚂蚁粉给药量按小鼠体重1.5 g/kg、0.75 g/kg、0.375 g/kg计算,连续10 d灌胃给药后,测定各组小鼠的体重、胸腺和脾脏重量,计算胸脾指数;检测中性粒细胞的吞噬率、T淋巴细胞E花环形成率及小鼠的溶血素效价和脾细胞介导的羊红细胞分光光度计定量测定法。

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