淋巴细胞
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Above mentioned results suggest that the inhibition of CD molecule expressed by the activated T lymphocyte, production of IL-2, the IL-2 receptor expression, and proliferation of MLR and T lymphocyte may be the one of the main immunosuppressive mechanism of cornus officinalis glycosides on the cell-mediated immunity.
以上说明抑制T淋巴细胞活化表达CD分子、IL-2的产生、IL-2受体的表达、MLR和T淋巴细胞的增殖可能是山茱萸总甙抑制机体细胞免疫功能的主要机理之一。
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Objective The study was conducted to investigate the effects of vitamin C polyphosphate on growth, lymphocyte proliferation and the content of serum corticosterone in heat-stressed and non-stressed mice.
目的探讨维生素C多聚磷酸酯对小鼠生长、淋巴细胞转化及血清皮质酮含量的影响以及淋巴细胞转化和血清皮质酮含量在热应激条件下的变化。
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The technique of separation lymphocytes of peripheral blood from Grass Carp (Ctenpharyngoden idellus Cuvier et Valencines) was explored.
通过对分离草鱼外周血淋巴细胞技术的探索,发现比重为1.080-1.085的Ficoll-Urografin或Percoll两种分离液均可将外周血中淋巴细胞100%地分离出来。
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After cultured with tumor cytolysis antigen for 2 days, the cells were incubated with auto T cell separated by E-rosette formation. Methyl thiazolyl tetrazolium assay was employed to test inhibition rate of tumor specific cytotoxic T lymphocyte on HO9810 tumor cell line. Results Our results indicated that DC precursors in cord blood can be induced to differentiate and mature in the medium containing IL-4, GM-CSF, and TNF-α.
将获得的DC与用 E-花环分离脐血单个核细胞得到的T淋巴细胞共同培养3 d,然后分为两组,实验组2继续与不同比例的HO9810细胞共同培养3 d后获得细胞毒T淋巴细胞,对照组2除加入HO9810外,还加入了无关细胞,用四甲基偶氮唑蓝法检测其对HO9810细胞的抑制作用。
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Objective: To investigate immunostimulatory activity of CpG ODN against immunosuppression mice, aged mice, pregnant mice and their newly born mice; To screen a CpG ODN that its immunostimulatory activity against human cord blood lymphocytes is stronger than others; To observe immunostimulatory activity of CpG ODN against premature infants cord blood lymphocytes and to observe its cytolysis against Kse2 cells.
摘要目的:探讨CpG ODN对免疫抑制小鼠、老年鼠、孕鼠及其新生小鼠的免疫刺激作用;筛选对人脐血淋巴细胞免疫刺激作用较强的一种CpG ODN;观察其对早产儿脐血淋巴细胞的免疫刺激作用及刺激NK细胞对K_(562)细胞的杀伤活性,为开发适合人类新型疫苗佐剂奠定基础。
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Results (1) Maximum bound volume and equilibrium dissociation constant of β2AR of lymphocyte in asthma patients at remission stage were markedly higher than that in normal subjects, while cAMP levels in blood plasma showed no difference.
结果缓解期哮喘患者外周淋巴细胞βAR的密度较正常人明显升高,血浆cAMP水平无显著差异,而发作期哮喘患者βAR及血浆cAMP水平均较正常人明显降低;缓解期哮喘患者外周淋巴细胞β2ARmRNA水平与正常人无显著差异。
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RESULTS: High and medium dose (30, 10 μg/kg) of selenocarrageenan syrupus increased mononuclear phagocyte englobement function, T lymphocyte proliferating function and delayed hypersensitivity significantly. All 3 doses increased serum haemolysin, IL-1, 2 activity and B lymphocyte proliferating function significantly.
结果:硒化卡拉胶口服液(30、10μg/kg)均可增强T淋巴细胞增殖能力及DTH;硒化卡拉胶口服液30、10、5μg/kg均可升高单核巨噬细胞吞噬功能、血清半数溶血素值,增强B淋巴细胞增殖能力及IL-1、IL-2活性。
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We tested the mononuclear phagocyte englobement function, serum haemolysin, delayed hypersensitivity, interlukine-1, 2(IL-1, 2) activity and T, B lymphocyte proliferating function.
测定小鼠单核巨噬细胞吞噬功能、血清半数溶血素值、迟发型变态反应、T淋巴细胞及B淋巴细胞增殖能力、白介素-1(IL-1)及白介素-2(IL-2)活性。
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Five models were used to investigate the "Changdong"" s anti-tumor effect: mice S180 sarcoma solid model, mice liver cancer H22 solid model, mice Lewis lung cancer model, as well as human liver cancer QGY and colon cancer LOVO implanted in naked mice; mice liver cancer H22 was also used to evaluate the enhancive effect of "Changdong" when it was co-applied with other anti-tumor agent or with radiotherapy; The "Changdong"" s cytotoxic effect in vitro on such tumors as QGY, LOVO, lung cancer A549, breast cancer MCF-7, as well as mice leukemia P388 was observed through MTT method. And investigate the effect of "Changdong" on proliferation of spleen lymphocyte, on activity of NK cell and on synthesis of IL-2 in mice bearing Lewis lung cancer, respectively. With propidium iodide straining, cell aigptosis and cell circle were analyzed by flow cytometry. Result:"Changdong" has an evident tumor inhibitive effect on mice tumor model as well as human tumor implanted in naked mice with a quantity-effect relationship.
使用小鼠S180肉瘤、小鼠肝癌H22实体瘤和小鼠Lewis肺癌模型,以及人体肝癌QGY和人体肠癌LOVO裸鼠异种移植模型,进行"长动"的抗肿瘤药效学研究:用小鼠肝癌H22进行"长动"合并放疗和化疗的增效作用研究;用MTT法进行"长动"对肝癌QGY、肠癌LOVO、肺癌A549、乳腺癌MCF-7、小鼠白血病P388等10株人体和动物肿瘤细胞的体外细胞毒性作用研究;用淋巴细胞转化试验、小鼠NK细胞活性试验、小鼠胸腺细胞增殖法分别测定"长动"对荷Lewis肺癌小鼠的脾淋巴细胞增殖的影响、自然杀伤细胞活性的影响和对小鼠产生白介素-2(IL-2)的影响;用流式细胞仪PI单染色法进行"长动"对人体肝癌QGY细胞的体外诱导凋亡作用和对肿瘤细胞周期的影响的研究。
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To date,it has been documented after transfusion of unirradiated blood components to at least 87 patients:in patients with severe combined immunodeficiency,thymic hypoplasia,and Wiskott Aldrich syndrome premature newborns and those with erythroblastosis fetalis; patients with hematologic malignancies including Hodgkin\'s and non-Hodgkin\'s lymphomas,acute myelocytic and lymphoblastic leukemias,chronic lymphocytic leukemia,and aplastic patients with solid tumors including neuroblastomas, glioblastoma,rhabdomyosarcoma,cervical carcinoma,small cell lung cancer,and germ cell tumor;patients after cardiac surgery and cholecystectomp-60;and in an apparently healthy 22-year-old woman.
目前为止,输注未辐照血液成分后,至少引起了87例TA-GVHD的发生,主要见于以下病人:严重的免疫缺陷病人、胸腺发育不全、Wiskott Aldrich综合症、早产儿、胎儿红细胞增多症、何杰金与非何杰金氏淋巴瘤等恶性血液病人、急性粒细胞性和淋巴细胞性白血病、慢性淋巴细胞性白血病、成神经细胞瘤等实体瘤病人、横纹肌赘瘤、宫劲癌、小细胞肺癌、微细胞瘤、心脏和胆囊手术病人。
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I will endeavour to find you some assistance.
我尽力帮你找人帮忙。
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At first I only know bruck is the idol of American younglings, afterwards I returned back to Taiwan ,even in Beijing last year ,I saw her poster everywhere, I was so surprised at her charm.
起初我只晓得布鲁克雷德丝是美国少男少女崇拜的偶像,后来回台湾,甚至去年在北京,居然也四处看见她的海报,才惊讶她的魅力之大。
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Ah may dee:You are chinese living in a democratic country.
你是居住在民主国家的中国人吧。