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淋巴细胞

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Luminal membrane stained more than 50%, was defined as AQPS-positive acinus. Randomly selected 100~110 acini to calculated the percentage of AQP5-positive acini.

同时计数切片中的淋巴细胞侵润灶,镜下观察测定组织的切面面积,从而计算出唇腺组织的淋巴细胞侵润灶评分。

The results indicated that albiflorin and paeoniflorin could improve activity of macrophage of mice, accelerate lympholyte multiplication,increase amount of active lympholyte,enhance immunity and confront with Cytoxan.

结果表明芍药双苷可恢复小鼠巨噬细胞吞噬功能,促进小鼠脾细胞诱导淋巴细胞增殖,增加具有活性淋巴细胞的数量,提高机体免疫力,并对环磷酰胺有一定拮抗作用。

Meanwhile we observed the change of symptoms, biopsy, T cell inferior group of serum (CD3、 CD4、CD8)、immunoglobulin (IgG、IgA、IgM) and the alexin (C3、C4), cAMP、 cGMP. CD3、CD4、CD8 are detected by immunomomoclonal antibodies APPAP; IgG、IgA、IgM are tested by immunoturbidimetry assay; the content of cAMP and cGMP in blood plasm are tested by radioimmunoassay.

所有观察病例于治疗前均作血、尿、大便常规化验;心、肝、肾功能检查;阴道分泌物检查包括念珠菌、滴虫、阴道清洁度;尿糖、血糖检查;分别观察中药组和西药组治疗前后相关症状及体征变化情况,活体组织病理检查的变化情况;血清T淋巴细胞亚群(CD3、CD4、CD8)和免疫球蛋白(IgG、IgA、IgM)以及补体(C3、C4)各项指标的变化情况;血中cAMP、cGMP含量变化情况,T淋巴细胞亚群水平测定采用单克隆抗体APAAP桥联酶标技术,血清免疫球蛋白IgG、IgA、IgM及补体C3、C4的测定采用免疫透射比浊法。

Methylation of CpG islands in the promoters induces gene silencing. The multiple tumor suppressor gene P16, located at chromosome 9p21, regulating normal proliferation of cells with a functional unit constituting of p16, cyclin D1 and pRb together. Methylation of P16 gene has been detected in several lymphocytic and plasmacytic malignancies such as lymphoma, acute lymphocytic leukemia and multiple myeloma and shows relationships with the pathogenesis of these diseases. Application of demethylation agents or arsenical to refresh the gene functions will be expected to be a new treatment for hemopoietic malignancies.

基因启动子区CpG岛甲基化常导致基因沉默。P16基因是一定位于9p21的多种肿瘤抑制基因,通过pl6INK4Acyclin D1-PRb通路维持机体细胞的有序增殖。P16基因甲基化在淋巴瘤、急性淋巴细胞性白血病、多发性骨髓瘤等多种淋巴细胞浆细胞肿瘤中被检测到,并与疾病的发生、发展存在一定关系,应用甲基化抑制因子或砷剂去甲基化治疗,恢复基因功能可望成为血液恶性肿瘤治疗的一种新手段。

The immunosuppressive effect was determined with ratio of lymphocyte blastogenesis,phagocytotic function of macrophage,percentage of peripheral T-lymphocyte,delayed type hypersensitivity and antibody forming cell assay.

免疫抑制作用:测定小鼠脾淋巴细胞转化率;巨噬细胞的吞噬功能;外周血T淋巴细胞的百分率;迟发性的变态反应;血清溶血素和抗体形成细胞功能测定。

Methods The inter-leukin2activity was observed by MTT colormietric assay,the interleukin2receptor expression of lymphocyte mem-brane was examined by immunofluoresence technique and lymphocyte blastogenesis in peripheral blood was measured by morphologic observation.

通过体外实验,运用MTT比色法、免疫荧光技术、淋巴细胞转化试验等实验方法,检测白细胞介素2活性、淋巴细胞膜白细胞介素2受体含量及外周血淋巴细胞转化功能。

Results Nasal tolerance could effectively prevent the development of EAE clinically. The erythrocyte rosette test, lymphocyte blastogenesis test and MBP-specific skin DTH response were also obviously suppressed. An evident increasing of IL-4 level while a decreasing of IFN-γ level was found after the culture of peripheral blood lymphocytes.

结果 鼻粘膜免疫耐受可有效地阻止EAE发生,耐受组动物E花环形成试验、淋巴细胞转化试验及DTH反应明显受到抑制,外周血淋巴细胞培养后测得白细胞介素-4 (IL-4)水平明显升高,γ-干扰素水平则明显降低。

The kinetics of T-cell subsets, blastogenic responses and anti-NDV serum IgG antibody of La Sota-immunized chicken were investigated using FACS, blastogenesis microassay and indirect ELISA after the chickens were thymusectomized.

然后,在不同的日龄分别用FACS、MTT及间接ELISA测定脾脏和外周血中CD4+和CD8+T淋巴细胞亚类数量、脾T淋巴细胞转化功能及病毒特异的血清IgG抗体的动态变化。

The second group of cells in the bursa similar to the organ or tissue by the hormone, mature and differentiate into other cell subsets, known as B lymphocytes.

第二个细胞群在类似法氏囊的器官或组织内受激素作用,成熟并分化为淋巴细胞的另一个亚群,被称为 B 淋巴细胞

HPCA was measured by using a one-stage plasma recalcification clotting time.Results The peripheral blood lymphocytes from rheumatic carditis patients can stimulate the procoagulant activity of human heart tissue cell in vitro.But the sera of rheumatic carditis patients and group A streptococcal cell membrane can not increase HPCA.

结果 患者的外周血淋巴细胞能使HPCA明显升高;静止期风心病、风湿性关节炎、其他疾病对照组及健康对照组患者的外周血淋巴细胞均无此特性,迁延活动型风湿性心脏炎患者的血清及A组乙型溶血链球菌膜抗原对HPCA也无直接影响。

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