淋巴细胞

The re-suits showed that IL level in serum of Ⅰ group goats decreased, whereas that of Ⅱ group goats increased, TNF-α levels in serum and IL-2 in supernatant with proliferation of PBL of goats increased after infection. PBL of goats was responsible for antigen 1 week after infection. Immune response of PBL of goats infected with Fasciola hepatica on the special and non-special antigen obviously increased. The results suggested that TNF-α would participate in the course of liver damage caused by Fasciola hepatica.

结果表明，山羊试验感染肝片吸虫后，Ⅰ组山羊血清IL-2水平在感染后有所下降，而Ⅱ组山羊血清IL-2水平在感染后有所升高；感染不同剂量肝片吸虫的山羊血清TNF-α水平和淋巴细胞IL-2分泌水平均有不同程度的升高，在感染后第1周淋巴细胞就有反应，并且对非特异性刺激原和特异性刺激原的应答都有显著升高。

The Collaborative Program in Developmental Biology is primarily dedicated to research and education in Developmental Biology including amphibian gastrulation, molecular control of hematopoiesis, lymphocyte lineage commitment and cell development, hematopoietic stem cells, lymphocyte development, cell enlargement and cell differentiation, vertebrate embryogenesis, developmental neurobiology.

动物学系发育生物学合作研究组主要致力于两栖动力原肠胚形成，造血作用的分子控制，淋巴细胞血统定型和细胞发育，造血干细胞，淋巴细胞发育，细胞生长和细胞分化，脊椎动物胚形成，发育神经生物学等。

The Collaborative Program in Developmental Biology is primarily dedicated to research and education in Developmental Biology including amphibian gastrulation, molecular control of hematopoiesis, lymphocyte lineage commitment and cell development, hematopoietic stem cells, lymphocyte development, cell enlargement and cell differentiation, vertebrate embryogenesis, developmental neurobiology.

动物学系发育生物学合作研究组主要致力于两栖动力原肠胚形成，造血作用的分子控制，淋巴细胞血统定型和细胞发育，造血干细胞，淋巴细胞发育，细胞生长和细胞分化，脊椎动物胚形成，发育？？？经生物学等。

To investigate the clonal rearrangements of immunoglobulin heavy chain gene and T-cell receptor γ gene in peripheral blood cells of patients with hemapoietic malignancies and their significance, the clonal rearrangements of IgH and TCRγ genes were detected by polymerase chain reaction in peripheral blood cells of patients with hemapoietic malignancies, including 32 cases of non-Hodgkin lymphoma, 18 cases of acute myeloid leukemia, 24 cases of multiple myeloma, 8 cases of acute lymphoblastic leukemia and 6 cases of chronic lymphoblastic leukemia.

检测各种血液系统肿瘤患者外周血细胞免疫球蛋白重链基因和T细胞受体γ基因克隆性重排并探讨其意义。通过多聚酶链式反应方法检测32例非霍奇金淋巴瘤、18例急性髓性白血病、24例多发性骨髓瘤、8例急性淋巴细胞白血病及6例慢性淋巴细胞白血病患者外周血细胞IgH及TCRγ克隆性基因重排。

Besides EB virus infection,others may also cause the number of heterotypic lymphocytes to increase.

结论除 EB 病毒感染容易引起异型淋巴细胞增多外，其它病毒感染同样会引起异型淋巴细胞的增多。

Methods Granulocyte/macrophage colony stimulating factors and interleukin 4 were used to cultivate DC from peripheral blood of hepatocellular carcinoma patients.Tumor associated antigen extracted from human liver cancer HepG2 cell line was used to activate the DC,which will initiate homogenic T lymphocyte to form cytotoxic T lymphocyte.HepG2 cells were transplanted to the nude mice and were treated with CTL.Expression of PCNA in tumor cells was evaluated.

联合应用粒/巨细胞集落刺激因子及白介素-4(IL-4)直接从肝癌患者外周血中培养出DC；以源于人肝癌细胞系HepG2细胞的肿瘤抗原粗提物刺激DC；DC激活同源的T淋巴细胞产生细胞毒性T淋巴细胞；建立人肝癌细胞系HepG2裸鼠移植瘤模型；CTL治疗人肝癌细胞系HepG2裸鼠移植瘤；检测移植瘤标本肿瘤细胞PCNA表达水平。

Immunorelated pancytopenia or hemocytopenia is a kind of disease with a relative clear pathological mechanism which was separated from bone marrow failure disease.It was thought to be caused by unbalance of T lymphocyte regulation and abnormal of B lymphocyte mount,subgroup,and function,which result in production of autoantibodies destroying or suppressing the inmature bone marrow hematopoietic cell and peripheral hypocytosis.

免疫相关性全血细胞减少或血细胞减少症是从骨髓衰竭性疾病中分离出的一种病理机制相对清晰的独立疾病体系，是由于T淋巴细胞调控失衡导致B淋巴细胞数量、亚群、功能异常，进而产生抗骨髓未成熟造血细胞自身抗体并破坏或抑制之，最终导致外周血细胞减少的一类疾病。

Objective: To investigate the situation of TCR Vβ gene repertoire and clonal expansion in peripheral blood T cells from patients with acute lymphoblastic leukemia and T cell strains, and analysis the expressive characters of TCR V β gene idiotype. To develop the anti-lymphoblastic leukemia TCR idiotypic DNA vaccine.

目的：了解淋巴细胞白血病及T细胞株的TCRVβ基因谱系及其克隆性增殖情况，分析TCR Vβ基因独特型表达的特点，并构建具有抗淋巴细胞白血病作用的TCR独特型DNA疫苗。

The experiments may contribute not only to investigating the mechanism of interaction between ldiotype and anti -idiotype T cells by which immune network are up-regulated, but also to analysing the suppressive effect of anti -idiotypic T cell or antibodies against the antigens on the activated T cells in the allo-responsiveness.

本课题选用小鼠耳后心肌移植模型，用同种抗原特异的活化T淋巴细胞免疫同系小鼠的方法，诱导免疫小鼠同种心肌移植物存活时间的延长，以此探讨免疫网络中独特型-抗独特型相互作用机理，着重分析在同种抗原诱导的免疫应答中，抗独特型T细胞和抗活化T淋巴细胞抗原抗体对同种免疫反应的抑制作用。

Be good at the lienal cure that change Yu can administer small environment of patient of cancer of the liver, correct the unusual expression of cellular factor and transcribe factor, change T lymphocyte inferior group unbalance condition, raise T lymphocyte active, enhance the T cell identifying to tumor cell function, immunity of changeover liver cancer escapes.

健脾化瘀治疗可治理肝癌患者微环境，纠正细胞因子和转录因子的异常表达，改变T淋巴细胞亚群的失衡状态，提高T淋巴细胞活性，增强T细胞对肿瘤细胞的识别功能，逆转肝癌免疫逃逸。

I will endeavour to find you some assistance.

我尽力帮你找人帮忙。

At first I only know bruck is the idol of American younglings, afterwards I returned back to Taiwan ,even in Beijing last year ,I saw her poster everywhere, I was so surprised at her charm.

起初我只晓得布鲁克雷德丝是美国少男少女崇拜的偶像，后来回台湾，甚至去年在北京，居然也四处看见她的海报，才惊讶她的魅力之大。