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Objective To explore livin, MTA1 and the caspase3 protein expression, their correlation and clinical pathology in colon cancer Methods The expressions of livin, MTA1 and caspase3 protein in 88 cases of colon cancer were detected by immunohistochemistry stainingResults Livin, caspase3 protein and MTA1 positive expression rates in colon cancer tissues were more than those in tissues beside the cancer Furthermore there were obvious relevance between livin protein, MTA1 positive expression rate and degree of histodifferentiation and lymph node metabasis and between caspase3 protein positive expression rate and degree of histodifferentiation of colon cancer Caspase3 protein expression had prominent inverse correlation with the livin expressionConclusions ①Over expression of livin having inhibtion on colon cancer is one of important factors of colon carcinogenesis ②Caspase3 protein expression in colon cancer tissues is inhibited to less and has prominent inverse correlation with livin expression Accordingly, suppressing caspase3 protein activity is one of channels, by which livin promotes colon carcinogenesis ③MTA1 plays the important role in histodifferentiation degree and lymph node metastasis of colon cancer

采用免疫组织化学染色方法检测88例结肠癌组织中Livin,Caspase3 及MTA1的表达情况。结果(1)结肠癌组织中Livin的阳性表达率显著高于癌旁组织,且Livin的表达与结肠癌的组织分化程度及淋巴结转移程度显著相关。(2)结肠癌组织中Caspase3蛋白的阳性表达率显著高于癌旁组织,且Caspase3蛋白的表达与结肠癌的组织分化程度显著相关。(3)结肠癌组织中MTA1的阳性表达率显著高于癌旁组织,且MTA1的表达与结肠癌的组织分化程度及淋巴结转移程度显著相关。(4)Caspase3蛋白的表达又与Livin的表达呈显著负相关。结论(1)Livin在结肠癌组织中过表达,它可能是促进结肠癌发生的重要因素之一。(2)Caspase3蛋白在结肠癌组织中表达被抑制而降低,且与Livin的表达呈负相关。因此,抑制Caspase3蛋白的活性是Livin促进结肠癌发生的途径之一。(3)MTA1对结肠癌的组织分化及淋巴转移发挥重要作用。

In the A and B figures, small grape - like tissue covered over all the epiglottic area that is hypertrophic lymphoid tonsil . More advanced the fiberoptic laryngoscope during spontaneous inspiration phase, larynx and vocal cord can be visualized in the C and D figures. We must emphasize that endotracheal intubation and even artificial ventilation was hardly performed under direct laryngocopy and general anesthesia .+{{: congress:2008:abstract:c01-1. jpg

图片A和B中,覆盖整个会厌部的葡萄息肉状物就是濔漫增生的舌底部淋巴组织增生,当光纤内视镜随著病人自主呼吸向内向下移动,吐气时可以见到图片C和D中喉头及声带的开合,由於在全身麻醉下无自主呼吸时此病人咽喉部位的似帘幕状遮蔽特殊结构造成之困难插管甚至是困难通气。

CD8~+ cell is the main T lymphocyte subset in spleen, and B lymphocyte mainly is IgG~+ cell, moreover the amount of these B lymphocytes could exceed CD3~+ T lymphocyte subset after 7 days. CD8~+ cell is the main T lymphocyte subset in tonsil of appendix, and B lymphocyte is IgM~+ cell, and the amount could exceed CD3~+ T lymphocytes after 35 days. After 21 days, B lymphocytes in esophago tonsil are the main IgA~+ cells and the amount exceeds CD3~+ lymphocytes. The amount of CD4~+ lymphocytes is more than CD8+ lymphocytes.4. CD3~+、CD4~+ and CD8~+ T lymphocytes in spleen mainly distribute in periarterial lymphoid sheath. However IgM~+、IgG~+ and IgA~+ cells mainly distribute in ellipsoid periarterial lymphoid sheath and germinal center. T lymphocytes in appendix tonsil mainly distribute in middle and inferior part of mucous and the B lymphocytes mainly in middle and mucous between 4~7 days. Whereafter T, B lymphocytes equably distribute in mucous. CD4~+ cells arrange tightly and mainly occupy the central part in aggregates of T lymphocytes in esophago tonsil and CD8~+ lymphocytes mainly distribute in periphery. Meanwhile B lymphocytes encircle the periphery of aggregates of T lymphocytes. The aggregates of B lymphocytes is mainly the germinal center with lots of IgM~+、IgG~+ and IgA~+ cells. Meanwihle T lymphocytes encircle the periphery of aggregates of B lymphocytes.5. There is an intimate relationship between the development of tissue structure of peripheral immune organs and lymphcytopoiesis. The maturation of tissue structure is stimulated by the immigration of lymphocytes and the mature tissue structure provides place where lymphocytes grow mature and functionate.

脾脏在21日龄时达到稳定,食管扁桃体和盲肠扁桃体均在35日龄时达到稳定;脾脏中T淋巴细胞亚群以CD8~+细胞为主,B淋巴细胞则以IgG~+细胞为主,并在7日龄后数量超过CD3~+T淋巴细胞;盲肠扁桃体中T淋巴细胞亚群以CD8~+细胞为主,B淋巴细胞以IgM~+细胞为主,并在35日龄后数量超过CD3~+T淋巴细胞;21日龄后,食管扁桃体中B淋巴细胞以IgA~+细胞为主,数量超过CD3~+细胞,CD4~+细胞的数量多于CD8~+细胞。4、在T、B淋巴细胞组织定位方面,脾脏中CD3~+、CD4~+和CD8~+T淋巴细胞主要分布在动脉周围淋巴鞘中,而IgM~+、IgG~+和IgA~+细胞主要分布在椭球周围淋巴鞘和生发中心中;4~7日龄时,盲肠扁桃体中T淋巴细胞主要分布在粘膜固有层的中下部区域,而B淋巴细胞则主要分布在中上部区域,随后各日龄T、B淋巴细胞均匀地分布在粘膜固有层中;在食管扁桃体的T淋巴细胞聚集物中,CD4~+细胞紧密排列,主要占据中央部位,CD8~+细胞主要散布在外周,同时B淋巴细胞又环绕在整个T淋巴细胞聚集物的外周;B淋巴细胞聚集物主要为生发中心,其中存在大量IgM~+、IgG~+和IgA~+细胞,同时T淋巴细胞又环绕在整个B淋巴细胞聚集物的外周。5、外周免疫器官的组织结构发育和淋巴细胞发生之间存在密切的关系,淋巴细胞迁入淋巴器官刺激组织结构的发育成熟,同时成熟的组织结构又为淋巴细胞发育成熟并行使功能活动提供场所。

Histiocytic necrotizing lymphadenopathy (Kikuchi's disease) is a rarely observed clinical entity characterized by fever and solitary or multiple lymphadenopathy predominantly in the posterior cervical region.

组织细胞坏死性淋巴病变(Kikuchi's disease,菊池氏病)为一种罕见的以发烧及主要侵袭后颈部单一性或多发性淋巴病变为特徵的临床疾病。

Traumatic or surgical injuries to this system can cause leakage of lymph and result in the formation of a lymphocele, which is defined as an accumulation of lymph surrounded by pseudomembranes (layers of tissue with a reaction of the surrounding tissue).10 Lymph drainage above the cisterna chyli is rich in chylomicrons and has a creamy white appearance because of the contribution of the gastrointestinal lymphatics.14 Below the cisterna chyli, however, lymph is serous in nature and has a clear yellow color and a significantly lower triglyceride content.

外伤或手术对这个系统造成损伤可以引起淋巴漏,最终导致淋巴管瘤形成。淋巴管瘤即为有假膜(由于四周组织反应形成的组织层)包裹的淋巴聚集。由于胃肠道淋巴的关系,在乳糜池以上的淋巴管富含乳糜微粒,有奶油样的白色外观。而乳糜池一下的淋巴则为浆液性质,为清亮黄色,其甘油三脂的含量明显降低。

This paper studied the effect of pollen rations on duodenum configuration and structure of growing-finishing swines, including the effect on the length and figure of intestinal villi, the length of duodenum secretory, amount of plasma cell and aggregated lymphoid nodules in membrana propria.

研究了蜂花粉对生长肥育猪十二指肠形态及组织结构的影响,考察了不同比例的蜂花粉对十二指肠绒毛长度及形态、肠腺长度、固有膜中的浆细胞、集合淋巴小结的影响。

Today,correct diagnosis of CAEBV and studying its pathogenesis are two hot researching points.But in the diagnosis process,we found the antibodies of CAEBV presenting diversity,which did not coincidence with the detect of EBV-DNA.Some CAEBV patients lack the elevation of the EBV antibodies if its immunoglobulin was low or had sthenic spleen function,but their EBV-DNA copies increased dramatically.Those having high EBV antibodies may be caused by the cross-reaction of other factors.

最初的关于CAEBV患儿的报道始于二十世纪八十年代初,CAEBV感染主要发生在小儿,而成年以后很少发病;CAEBV感染在亚洲发病率高,随访8月至12年死亡率43%,而且与多种临床疾病,特别是与EBV相关的T、NK淋巴细胞增殖综合征、噬血细胞性淋巴组织细胞增生症和恶性淋巴瘤等预后不良的疾病密切相关,所以CAEBV越来越受到研究者们的关注。

Prove that the soap glucoside of ginsengs is a kind of very good immunity strengthens the pharmaceutical through animals experiment, It is strengthening the systematic function of single-nuclear macrophage cell, promotes the formulation antibody and lymphocyte transformed, Promote some lymph secretion of factor, play a regulating role in natural killer cell-interferon-IL-2 regulate network, and protect the organization cell attacked by the virus.

通过动物实验证明人参皂甙是一种很好的免疫增强剂,它具有扶正固本、增强单核巨噬细胞系统功能,促进特异性抗体的生成和淋巴细胞转化,促进某些淋巴因子的分泌,对天然杀伤细胞-干扰素-白介素-2调节网起正调节作用,并能保护受病毒侵袭的组织细胞。

Objective To observe the morphological changes of pancreatic tissue of thoracic duct ligated rats in fine and ultrastructural levels, and to determine whether lymph block animal model can affect pancreatic islet amyloid polypeptidedeposit in rat pancreas.

目的 观察胰淋巴淤滞动物模型胰组织结构变化和胰淀肽沉积情况,探讨淋巴淤滞对胰组织细微和超微结构的影响。

In addition, hindgut has also been analysed, as studies have suggested that numerous lymphoid cells occur at this location in the lamina propria and the submucosa. The Ig-bearing cells are also found in the epithelial layer occasionally.

研究牙鲆黏膜样淋巴组织结果显示在牙鲆的后肠中存在大量产生免疫球蛋白的淋巴细胞,主要分布于后肠的固有层和粘膜下层中,在粘膜层和粘膜层表面也偶有极少量的产生免疫球蛋白的淋巴细胞出现。

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