淋巴瘤的

Objective The origin and the nature of the Hodgkin and Reed-Sternberg cell of Hodgkins lymphoma has been attracting a lot of medical researchers engaged in studying it,for its character by scattered large atypical cells residing in a complex admixture of inflammatory cells.Great improvement has been made since a new method of isolation of single H/RS cells from a frozen section had been set up by KUppers in 1994,and many studies have approved of the B-cell derivation of H/RS cell.lt has been reported that H/R-S cells might partly be originated from B-cell in our research before,but at the same time,we also found that only 18.8% of H/RS cells express CD20,31.3% of immunoglobulin heavy chain rearrangement have been revealed.

目的 霍奇金淋巴瘤(Hodgkins lymphoma，HL)由于它的恶性肿瘤细胞—H／RS细胞一般只占肿瘤组织的极少部分(不到1％)，且散在分布在背景细胞间，因此对于H／RS细胞的来源和性质研究一直是人们探索的目标。1994年德国科隆大学Kūppers等发展了一种从冰冻组织切片上用显微操作仪挑取单个H／RS细胞的显微切割方法进行H／RS细胞基因分析后，人们对H／RS细胞来源的研究有了突破性的进展，多数支持B细胞来源。

Results In 9 cases of endometrial biopsy of materials by uterine curettage, the cells of endometrial stromal sarcomas of 6 cases were well differentiated and like stromal cells of endometrial hyperplasia; the cells of endometrial stromal sarcomas of 3 cases were poor differentiated, the cells of 2 were like that of malignant lymphoma, and another like that of pleomorphous sarcoma. In 9 cases were found the distribution of vessels cluster like endometrial corkscrew small artery. The tumor cells were grew along lymphatic or protruded in lymphatic, and there were small islands or small pieces of tumor cells in the interspace of muscles in 2 cases. The contrastive observation of the specimens of resected uterines of 9 cases confirmed the valve of above features to the confessed diagnosis of endometrial stromal sarcomas in the materials of endometrial biopsy or uterine curettage.

有3例分化差者，其中2例酷似恶性淋巴瘤，1例酷似多形性肉瘤。9例均见簇状分布的子宫内膜螺旋小动脉样的小血管分布，2例见瘤组织沿淋巴管和突入淋巴管内生长及小片平滑肌组织的肌间隙内有小灶状或小片状瘤组织分布。9例子宫切除标本的对比观察，进一步证实了上述特征对宫内膜活检或刮出物确诊子宫内膜间质肉瘤的价值。

Today,correct diagnosis of CAEBV and studying its pathogenesis are two hot researching points.But in the diagnosis process,we found the antibodies of CAEBV presenting diversity,which did not coincidence with the detect of EBV-DNA.Some CAEBV patients lack the elevation of the EBV antibodies if its immunoglobulin was low or had sthenic spleen function,but their EBV-DNA copies increased dramatically.Those having high EBV antibodies may be caused by the cross-reaction of other factors.

最初的关于CAEBV患儿的报道始于二十世纪八十年代初，CAEBV感染主要发生在小儿，而成年以后很少发病；CAEBV感染在亚洲发病率高，随访8月至12年死亡率43%，而且与多种临床疾病，特别是与EBV相关的T、NK淋巴细胞增殖综合征、噬血细胞性淋巴组织细胞增生症和恶性淋巴瘤等预后不良的疾病密切相关，所以CAEBV越来越受到研究者们的关注。

The suspicion of cancer is increased by the following factors:(1) age (young patients are more susceptible);(2) sex, if the patient is a man (more women have thyroid cancer by a ratio of 2:1, but women have more thyroid disease by a ratio of about 8:1; thus, a man with a nodule should be regarded with greater suspicion);(3) a solitary nodule (multinodular lesions are usually benign unless there is a dominant cold nodule by thyroid scan);(4) a cold nodule on thyroid isotopic scanning (hot nodules are seldom cancerous);(5) a history of radiation exposure to the head, neck, or chest, especially in infancy and childhood (eg, for an enlarged thymus or enlarged tonsils, acne, or lymphoma);(6) radiographic evidence of fine, stippled psammomatous calcification or dense, homogeneous calcification;(7) recent or rapid enlargement; and (8) stony-hard consistency.

下列因素可增加癌的可疑性：(1)年龄；(2)性别，如果病人为男性(女性与男性的甲状腺癌比为2：1，但女性更多的是得甲状腺病，约为8：1，因此，男性有甲状腺结节时应考虑癌的可能性更大)；(3)孤立小结(多结节病变一般为良性，除非甲状腺扫描时呈明显的冷结节)；(4)甲状腺同位素扫描时发现冷结节；(5)有过头、颈、胸放射接触史，尤其是婴儿和儿童期(例如，因胸腺增大或扁桃体肿大、痤疮或淋巴瘤等)；(6)X线片见细、斑点状、沙粒样钙化或致密、匀质钙化；(7)最近增大或快速增大；(8)质地石头样坚硬。

To investigate the expression of T lymphoma invasion and metastasis inducing factor 1 (Tiam 1) in tissues of thyroid carcinoma, and to analyze the relation between its expression and invasion and metastasis of thyroid carcinoma.

王化修，甲状腺癌中Tiam 1的表达及临床意义目的探讨T淋巴瘤侵袭转移诱导因子1的表达与甲状腺癌侵袭转移的关系。方法采用免疫组织化学S-P法检测Tiam1在89例甲状腺癌及其淋巴结转移癌的石蜡组织标本中的表达。

I will endeavour to find you some assistance.

我尽力帮你找人帮忙。

At first I only know bruck is the idol of American younglings, afterwards I returned back to Taiwan ,even in Beijing last year ,I saw her poster everywhere, I was so surprised at her charm.

起初我只晓得布鲁克雷德丝是美国少男少女崇拜的偶像，后来回台湾，甚至去年在北京，居然也四处看见她的海报，才惊讶她的魅力之大。