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Methods Tissue arrayer was used to create a 252-dot tissue microarray, consisting of 84 cases of malignant lymphomas arising in esophagus, stomach, intestines, thyroid, saliva gland , orbital cavity and lung, Seven cases of diffuse large B cell lymphomas,9 adenocarcinomas, 1 neuroendocrine tumor,1 squamous carcinoma, 6 T-cell lymphomas and 18 reactive lymphoid nodes were also included as control in the microarray.

建立包含84例MALT型淋巴瘤、7例弥漫性大B细胞淋巴瘤、9例腺癌、1例神经内分泌肿瘤、1例鳞癌、6例T细胞性非何杰金淋巴瘤和18例正常淋巴结共252点阵的组织芯片,应用免疫组织化学检测Ki-67、TopoⅡα、p53、Bcl-2、Bax、C-myc和Bcl-10在MALT型淋巴瘤中的表达情况。

CT display: In the small intestine:The boiler of the small intestine was thicker and the appearance was broadened;In the sinonasal cavity:The appearance of the middle and inferior turbinates were enlarged and the infiltrateive bone destruction,the affected paranasal sinuses were filled with soft tissues and sinus walls demonstrated bone infiltration; In the lungs:The repeatedly pneumonia happened in the same part for a long time and had a slowly speeding and it had normal bronchorrhagia.

小肠黏膜相关淋巴瘤表现为肠壁增厚、肠腔扩大;鼻腔黏膜相关淋巴瘤表现为鼻甲增大、鼻甲骨质虫蚀状破坏,鼻窦骨质破坏以及窦腔内软组织肿块;肺黏膜相关淋巴瘤表现为同一部位不易消散的、缓慢进展的节段性炎症,炎症区域支气管气像正常。

The National Cancer Institute, the National Institutes of Health, and Corixa supported this study. Corixa employs one of the authors and has various financial arrangements with several other authors. Some of the authors report potential financial conflicts of interest with GlaxoSmithKline. Two authors receive royalties from patents they jointly hold on anti-CD20 radioimmunotherapy for lymphoma, and they have been expert witnesses in defending these patents.

国家癌症机构、国家卫生研究院及Corixa赞助这项试验;Corixa雇用其中一位研究人员,而且许多其他研究人员接受该公司的资金赞助;某些研究人员表示与葛兰素药厂有潜在资金上的冲突;两位研究人员接受来自病患的专利权费,这两位共同拥有抗CD20放射线免疫疗法治疗淋巴瘤的专利,且他们一直是保护这些病患的专家证人。

The National Cancer Institute, the National Institutes of Health, and Corixa supported this study. Corixa employs one of the authors and has various financial arrangements with several other authors. Some of the authors report potential financial conflicts of interest with GlaxoSmithKline. Two authors receive royalties from patents they jointly hold on anti-CD20 radioimmunotherapy for lymphoma, and they have been expert witnesses in defending these patents.

国家癌症机构、国家卫生研究院及Corixa赞助这项试验;Corixa雇用其中一位研究人员,而且许多其它研究人员接受该公司的资金赞助;某些研究人员表示与葛兰素药厂有潜在资金上的冲突;两位研究人员接受来自病患的专利权费,这两位共同拥有抗CD20放射线免疫疗法治疗淋巴瘤的专利,且他们一直是保护这些病患的专家证人。

Three cases of advanced NHL associated with lymphomatous leptomeningitis were reported with a review of the literature.Two of the patients were poorly differenti- ated lymphocytic lymphoma,diffuse type,and the other Burkitt's lymphoma.

本文报告3例淋巴瘤性脑膜炎,并复习文献讨论淋巴瘤脑膜炎的诊断、治疗和预防。3例患者均为晚期非何杰金氏淋巴瘤。1例为低分化淋巴细胞淋巴瘤弥漫型,1例为 Burkitt's 淋巴瘤。

The mean ADC value of lymphomatous, metastatic and benign lymph nodes was (0.874±0.17)×10~(-3)mm~2/s,(0.98±0.09)×10~(-3)mm~2/s and (1.20±0.10)×10~(-3)mm~2/s. There was statistically different between benign lymph nodes and other groups (P=0.00). When an ADC value of 1.085×10~(-3)mm~2/s was used as a threshold value for differentiating malignant from benign lymph nodes, the best results were obtained with an sensitivity of 87.8% and specificity of 91.3%. 16 of 18 cases (88.9%) were accurately staged in accordance with clinical staging. For 24 patients after chemotheraphy or radiotheraphy, 4 cases were complete remission and WB-DWI was negative. WB-DWI was positive in 14 of 17 cases with recurrent or remnant tumor. For 3 patients with suspected partial remission, WB-DWI indicated necrosis in 2 cases and inactive in 1 case. Repeated WB-DWI examination was performed in 13 cases, tumors were eradicated in 6 cases, improved in 4, expanded in 2. A new colon carcinoma besides its primary lesion was found in 1 case. The results of WB-DWI were all concordant with other clinical tests.

以ADC值1.085×10~(-3)mm~2/s作为诊断恶性淋巴结病变的临界值,敏感性及特异性分别为87.8%和91.3%。88.9%(16/18)患者WB-DWI检查后分期与临床分期一致。24例淋巴瘤患者放化疗后行WB-DWI检查,4例临床疗效为完全缓解,WB-DWI检查均为阴性,17例临床确认有肿瘤复发及明显残留,WB-DWI显示为阳性的14例,另外3例常规影像评价为部分缓解的患者,WB-DWI检查提示2例病灶以坏死液化为主,1例病灶无明显活性。13例淋巴瘤患者行多次WB-DWI检查,发现6例治疗后病灶消失,4例缓解,1例原发病灶缓解,新出现结肠癌,2例淋巴瘤进展,皆与临床相符。

Objective:To evaluate treatment method, result and main cause of failure and prognostic factors of tonsillar Non Hondgkin's lymphoma.

目的 :分析扁桃体非霍奇金淋巴瘤的治疗方法、治疗效果及治疗失败的主要原因,并探讨影响预后的主要因素。

Save yourself some money and study up on the proper way of handling your official nhl jersey.

自己节省一些钱,研究处理您的官方非霍奇金淋巴瘤的球衣正确的做法了。

Lusters of CD123+PDC were observed in all PCMZL (23 of 23 cases; 100%) and in two-thirds of cutaneous B-cell pseudolymphomas (14 of 22; 64%), but only in a minority of primary cutaneous follicle center lymphoma (4 of 31; 13%) and not in primary cutaneous diffuse large B-cell lymphoma, leg type.

D123+PDC成簇出现于所有PCMZL病例(所有23例,100%)和三分之二的皮肤B细胞假性淋巴瘤中(22例中有14例;64%),不出现在皮肤原发性弥漫大B细胞淋巴瘤,皮肤原发性滤泡性淋巴瘤只有个别病例出现(31例中有4例,13%)。

This experiment try to investigate the expressions of Epstein-Barr virus latent membrane protein 1(LMP-1),nuclear factor κ gene bindingand the apoptotic index in nasal NK/T cell lymphoma,and probe into the correlation of LMP-1 with NF-κB,AI,analyze their roles in the occurrence and development of nasal NK/T cell lymphomaMethods:From 1999 to 2004 ,26 cases of nasal NK/T cell lymphoma and 10 cases of benign lymph follicle hyperplasia were selected from Department of Pathology in Hospital of Shangdong province .

目的:EB病毒Epstein-Barr virus在鼻NK/T细胞淋巴瘤(nasal NK/T cell lymphoma)的瘤细胞的检出率较高,但其在淋巴瘤发生发展中的确切作用尚不清楚,本研究通过检测鼻腔NK/T细胞淋巴瘤中EB病毒感染潜伏膜蛋白(latent membrane protein-1,LMP-1)与细胞因子κB(nuclear factor κ gene binding,NF-κB)的表达及其细胞凋亡指数(apoptotic index,AI),比较三者间相互关系,分析EB病毒在鼻NK/T细胞淋巴瘤发生发展中的致瘤机制。

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