淋巴瘤

E studied expression levels of WAVE1 in six leukemia cell lines (the human Jurkat T leukemia cells, U937 histiocytic lymphoma cells, Burkitts lymphoma cell Raji, acute promyelocytic leukemia cell HL-60, chronic myelogenous leukemia cell K562 and K562/A02) by Western blotting analysis. Levels of WAVE1 expression were high in all six human leukemia cancer cell lines. In contrast, the constitutive expression levels of WAVE1 were noticeably lower in normal human peripheral blood mononuclear cells, or non-blood cancer cell-lines, including human lung A549 cancer cells, Hela cervical cancer cells, MG-63 osteosarcoma cells, CNE2 nasopharyngeal carcinoma cells, human umbilical vein endothelial cell, QSG7701 hepatocarcinoma cells, and WI-38 lung fibroblastoma cells.

AVE1在人类血液肿瘤细胞系(人T细胞白血病细胞系Jurkat、人组织细胞淋巴瘤细胞系U937、人Burkitts淋巴瘤细胞系Raji、人原髓细胞白血病细胞系HL-60、人慢性髓原白血病细胞系K562和K562／A02)中高表达，在非血液肿瘤细胞系(人肺腺癌细胞系A549、人宫颈癌细胞系Hela、人成骨肉瘤细胞系MG-63、人鼻咽癌细胞系CNE2、人脐静脉内皮细胞系HUVEC、人肺成纤维细胞系WI-38、人肝上皮细胞系QSG7701)以及正常人外周血单个核细胞中低表达或不表达。

Objective Primary lymphoma in the central nervous system is rare.In order to recognize it tree cases of primary leptomeningeal lymphoma were presented in this article.

目的 原发性中枢神经系统淋巴瘤很少见，本文报告3例原发性中枢神经系统淋巴瘤，以提高人们对本病的认识。

Objective To observe the expression of multi-drug-resistant gene (MDR-1) and P-glucoprotein in malignant lymphomatous tissues and the drug-resistant mechanism of malignant lymphoma.

目的 观察多药耐药基因(MDR -1)及P -糖蛋白在恶性淋巴瘤组织中的表达情况，探讨恶性淋巴瘤的耐药机理。

Mesenteric lymph node involvementby lymphoma is not always associated with lymphomatous involvementof the small or large bowel.

肠系膜淋巴结淋巴瘤并不常伴随大、小肠淋巴瘤的发生。

The clinical features included peripheral lymphadenopathy and skin lesions, recurrent fever was very common. the pathological features included partial lymphomatous involvement of lymph node, sheets of analplastic large cells infiltrated the sinuses and paracortices, immunohistochemical cd30 was strongly positive. the prognosis was comparative well.

结果：间变性大细胞性淋巴瘤占小儿非霍奇金淋巴瘤的12.8%，临床表现主要是外周淋巴结肿大及皮肤损害，长期反复发热常见，病理特征为淋巴结部分受累，成片异形大细胞侵犯淋巴窦及副皮质区，免疫组化cd30强阳性，预后相对较好。

FDG-PET was compared with computed tomography and bone marrow biopsy to detect lymph node/extranodal lymphopathy and bone marrow infiltration.

使用国际工作组织淋巴瘤疗效标准和修订的国际工作组织淋巴瘤疗效标准评估患者的疗效。

Results The pathology of all 10 cases of nasal lymphomas were T cell Non-Hodgkin's lymphoma, Ann Arbor stage Ⅰ～Ⅱin9 and 1 in stage IV. The locations of 10 lymphomae were in the anterior portion of one of the nasal cavities, and the lymphomae extended posteriorly along the inferior and/or media nasalis concha in different extent. No bone structure destruction was found in all stage I cases and the bone of the media nasalis concha as well as the uncinate process was partially absorbed in the stage IV nHL. The skin of the external noses adjacent to the lymphoma of the whole 10 cases were swollen in various severity with disappearance of the subcutaneous fat.

结果 10例鼻腔淋巴瘤病理均为T细胞非何杰金淋巴瘤，9例为Ann arbor I～II期，1例Ann Arbor IV期。10例病变均发生于一侧鼻腔前部，沿下鼻甲向后呈不同程度蔓延。9例I期病变均无骨质破坏，相邻鼻背侧皮肤不同程度肿胀，皮下脂肪消失，1例IV期病变可见患侧中鼻甲及钩突骨质部分吸收，同侧眶内肿瘤侵犯。

Methods Paraffin-embedded tissues of34cases of nasal NK/T-cell lymˉphoma,8midline B-cell lymphomawere studied using immunohistochemical method.

以NK/T淋巴瘤34例石蜡组织标本为对象，同部位B细胞淋巴瘤8例为对照，行免疫组织化学染色。

Methods Paraffin-embedded tissues of34cases of nasal NK/T-cell lymˉphoma,8midline B-cell lymphomawere studied using immunohistochemical method.

以NK/T淋巴瘤34例石蜡组织标本为研究对象，同部位B细胞淋巴瘤8例为对照，行免疫组织化学染色。

LL2 is a murine IgG2a antibody to the CD_(22) antigen,We observed its efficacy and toxicity of ~(131)I-labelled-LL2 in the treatment of patients with recrudescent non-Hodgkin lymphoma.

LL2是鼠源性抗CD22抗体，通过131I标记LL2用于复发的非霍奇金淋巴瘤的治疗，观察其疗效及毒副作用。Epratuzumab是人源化的LL2抗体，通过对套细胞淋巴瘤的Ⅰ/Ⅱ期临床试验研究，其有效率为18%，不产生人抗鼠抗体。

I will endeavour to find you some assistance.

我尽力帮你找人帮忙。

At first I only know bruck is the idol of American younglings, afterwards I returned back to Taiwan ,even in Beijing last year ,I saw her poster everywhere, I was so surprised at her charm.

起初我只晓得布鲁克雷德丝是美国少男少女崇拜的偶像，后来回台湾，甚至去年在北京，居然也四处看见她的海报，才惊讶她的魅力之大。